ENSMUSG00000071691


Mus musculus

Features
Gene ID: ENSMUSG00000071691
  
Biological name :Gm960
  
Synonyms : Gm960 / J3QMY9 / Type 2 DNA topoisomerase 6 subunit B-like
  
Possible biological names infered from orthology : C11orf80 / chromosome 11 open reading frame 80 / Q8N6T0
  
Species: Mus musculus
  
Chr. number: 19
Strand: -1
Band: A
Gene start: 4625734
Gene end: 4698668
  
Corresponding Affymetrix probe sets: 10464793 (MoGene1.0st)   
  
Cross references: Ensembl peptide - ENSMUSP00000094049
Ensembl peptide - ENSMUSP00000136515
Ensembl peptide - ENSMUSP00000153439
NCBI entrez gene - 381196     See in Manteia.
MGI - MGI:2685806
RefSeq - XM_017318241
RefSeq - XM_017318238
RefSeq - XM_017318239
RefSeq - XM_017318240
RefSeq - NM_001033447
RefSeq - XM_011248634
RefSeq - XM_011248635
RefSeq - XM_011248636
RefSeq - XM_011248637
RefSeq - XM_011248638
RefSeq - XM_011248639
RefSeq - XM_017318231
RefSeq - XM_017318233
RefSeq - XM_017318234
RefSeq - XM_017318235
RefSeq - XM_017318237
RefSeq Peptide - NP_001028619
swissprot - J3QMY9
swissprot - A0A182DWE7
Ensembl - ENSMUSG00000071691
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 zgc:195212ENSDARG00000075203Danio rerio
 Q8N6T0ENSG00000173715Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
No match


Protein motifs (from Interpro)
Interpro ID Name
 IPR028040  Type 2 DNA topoisomerase 6 subunit B-like


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0007131 reciprocal meiotic recombination IMP
 biological_processGO:0042138 meiotic DNA double-strand break formation IEA
 biological_processGO:0051321 meiotic cell cycle IEA
 cellular_componentGO:0005575 cellular_component ND
 cellular_componentGO:0005694 chromosome IEA
 molecular_functionGO:0003918 DNA topoisomerase type II (ATP-hydrolyzing) activity TAS
 molecular_functionGO:0005515 protein binding IPI


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0001147 small testis "reduced size of the male reproductive glands" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:58959]
Show

Allelic Composition: Cnga3cpfl5/Cnga3cpfl5
Genetic Background: B6.RHJ-Cnga3cpfl5/BocJ

Allelic Composition: Gm960em2Arte/Gm960em2Arte
Genetic Background: involves: C57BL/6NTac

 MP:0001930 abnormal meiosis "malfunction in the process of nuclear division that results in gametes with one half the normal number of the original cell" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]
Show

Allelic Composition: Cnga3cpfl5/Cnga3cpfl5
Genetic Background: B6.RHJ-Cnga3cpfl5/BocJ

Allelic Composition: Gm960em2Arte/Gm960em2Arte
Genetic Background: involves: C57BL/6NTac

 MP:0005159 azoospermia "absence of living spermatozoa " [Stedman s Medical Dictionary:ISBN 0-683-40008-8]
Show

Allelic Composition: Cnga3cpfl5/Cnga3cpfl5
Genetic Background: B6.RHJ-Cnga3cpfl5/BocJ

Allelic Composition: Gm960em2Arte/Gm960em2Arte
Genetic Background: involves: C57BL/6NTac

 MP:0008261 arrest of male meiosis "cessation of the progression of the process of nuclear division that results in sperm with one half the normal chromosome number of the original cell" [ISBN:0-683-40008-8 "Stedman s Medical Dictionary, 27th edition"]
Show

Allelic Composition: Cnga3cpfl5/Cnga3cpfl5
Genetic Background: B6.RHJ-Cnga3cpfl5/BocJ

Allelic Composition: Gm960em2Arte/Gm960em2Arte
Genetic Background: involves: C57BL/6NTac

 MP:0009452 abnormal synaptonemal complex "an anomaly in the formation of the proteinaceous structure involved in the pairing of homologous chromosomes during first prophase of meiosis" [MGI:llw2 "Linda Washburn, Mouse Genome Informatics Curator"]
Show

Allelic Composition: Cnga3cpfl5/Cnga3cpfl5
Genetic Background: B6.RHJ-Cnga3cpfl5/BocJ

Allelic Composition: Gm960em2Arte/Gm960em2Arte
Genetic Background: involves: C57BL/6NTac

 MP:0011121 decreased primordial ovarian follicle number "fewer than normal numbers of the ovarian follicle in which the primary oocyte is surrounded by a single layer of flattened follicular cells; primordial follicles are indiscernible to the naked eye and develop to primary, secondary, and finally mature vesicular follicles" [MGI:csmith]
Show

Allelic Composition: Cnga3cpfl5/Cnga3cpfl5
Genetic Background: B6.RHJ-Cnga3cpfl5/BocJ

Allelic Composition: Gm960em2Arte/Gm960em2Arte
Genetic Background: involves: C57BL/6NTac

 MP:0011125 decreased primary ovarian follicle number "fewer than normal numbers of the ovarian follicle prior to the appearance of an antrum, normally marked by developmental changes in the primary oocyte and follicular cells so that the latter form one or more layers of cuboidal or columnar cells; the follicle becomes surrounded by a sheath of stroma, the theca" [MGI:csmith]
Show

Allelic Composition: Cnga3cpfl5/Cnga3cpfl5
Genetic Background: B6.RHJ-Cnga3cpfl5/BocJ

Allelic Composition: Gm960em2Arte/Gm960em2Arte
Genetic Background: involves: C57BL/6NTac

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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