ENSMUSG00000072945


Mus musculus

Features
Gene ID: ENSMUSG00000072945
  
Biological name :Ripply1
  
Synonyms : Protein ripply1 / Q2WG77 / Ripply1
  
Possible biological names infered from orthology : Q0D2K3 / ripply transcriptional repressor 1
  
Species: Mus musculus
  
Chr. number: X
Strand: -1
Band: F1
Gene start: 139779549
Gene end: 139782353
  
Corresponding Affymetrix probe sets: 10606941 (MoGene1.0st)   
  
Cross references: Ensembl peptide - ENSMUSP00000098778
NCBI entrez gene - 622473     See in Manteia.
MGI - MGI:3614797
RefSeq - NM_001037915
RefSeq Peptide - NP_001033004
swissprot - Q2WG77
Ensembl - ENSMUSG00000072945
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 Q0D2K3ENSG00000147223Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Q2WG76 / Ripply2 / Protein ripply2 / Q5TAB7* / ripply transcriptional repressor 2*ENSMUSG0000004789722


Protein motifs (from Interpro)
Interpro ID Name
 IPR028127  Ripply family
 IPR032675  Leucine-rich repeat domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0000122 negative regulation of transcription by RNA polymerase II IBA
 biological_processGO:0001757 somite specification ISS
 biological_processGO:0006351 transcription, DNA-templated IEA
 biological_processGO:0006355 regulation of transcription, DNA-templated IEA
 biological_processGO:0007219 Notch signaling pathway IGI
 biological_processGO:0007275 multicellular organism development IEA
 biological_processGO:0009880 embryonic pattern specification ISS
 biological_processGO:0010468 regulation of gene expression IGI
 biological_processGO:0032525 somite rostral/caudal axis specification ISS
 biological_processGO:0045892 negative regulation of transcription, DNA-templated ISS
 biological_processGO:0060349 bone morphogenesis IMP
 cellular_componentGO:0005634 nucleus IBA
 molecular_functionGO:0003674 molecular_function ND


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0000137 abnormal vertebrae morphology "malformed bony segment of the spinal column" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8]
Show

Allelic Composition: Ripply1tm1.1Sjt/Ripply1tm1.1Sjt,Ripply2tm1.1Ysa/Ripply2tm1.1Ysa
Genetic Background: involves: 129S1/Sv * C57BL/6 * CBA * FVB/N

Allelic Composition: Ripply1tm1.1Sjt/Y,Ripply2tm1.1Ysa/Ripply2tm1.1Ysa
Genetic Background: involves: 129S1/Sv * C57BL/6 * CBA * FVB/N

 MP:0000140 absent pedicles "loss of part of the posteriorlateral vertebral arch of a thoracic vertebrae" [J:62022, J:62023]
Show

Allelic Composition: Ripply1tm1.1Sjt/Ripply1tm1.1Sjt,Ripply2tm1.1Ysa/Ripply2tm1.1Ysa
Genetic Background: involves: 129S1/Sv * C57BL/6 * CBA * FVB/N

Allelic Composition: Ripply1tm1.1Sjt/Y,Ripply2tm1.1Ysa/Ripply2tm1.1Ysa
Genetic Background: involves: 129S1/Sv * C57BL/6 * CBA * FVB/N

 MP:0003048 abnormal cervical vertebrae morphology "malformation of any or all of the seven bony segments of the spine located anterior to the thoracic vertebrae" [MeSH:National Library of Medicine - Medical Subject Headings, 2003, csmith:Cynthia L. Smith, Mouse Genome Informatics Curator]
Show

Allelic Composition: Mpp5tm1Caw/Mpp5tm1Caw,Tsc2tm1.1Mjg/Tsc2tm1.1Mjg,Emx1tm1(cre)Krj/Emx1+
Genetic Background: involves: 129S1/Sv * 129S2/SvPas * 129X1/SvJ

Allelic Composition: Ripply1tm1.1Sjt/Ripply1tm1.1Sjt
Genetic Background: involves: 129S1/Sv * FVB/N

 MP:0008530 abnormal rostral-caudal patterning of the somites "anomaly in the developmental pattern of the somites along the axis that runs from the head to the caudal region of the body" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]
Show

Allelic Composition: Ripply1tm1.1Sjt/Ripply1tm1.1Sjt,Ripply2tm1.1Ysa/Ripply2tm1.1Ysa
Genetic Background: involves: 129S1/Sv * C57BL/6 * CBA * FVB/N

Allelic Composition: Ripply1tm1.1Sjt/Y,Ripply2tm1.1Ysa/Ripply2tm1.1Ysa
Genetic Background: involves: 129S1/Sv * C57BL/6 * CBA * FVB/N

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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