ENSMUSG00000073878


Mus musculus

Features
Gene ID: ENSMUSG00000073878
  
Biological name :Gm13304
  
Synonyms : Gm13304 / P86792 / P86793 / predicted gene 13304
  
Possible biological names infered from orthology : CCL21 / C-C motif chemokine ligand 21 / O00585
  
Species: Mus musculus
  
Chr. number: 4
Strand: 1
Band: A5
Gene start: 42114817
Gene end: 42115917
  
Corresponding Affymetrix probe sets: 10504127 (MoGene1.0st)   10504154 (MoGene1.0st)   10504183 (MoGene1.0st)   10512377 (MoGene1.0st)   1419426_s_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000095727
NCBI entrez gene - 100504346     See in Manteia.
MGI - MGI:3710514
RefSeq - NM_001193666
RefSeq Peptide - NP_001180595
swissprot - P86792
swissprot - P86793
Ensembl - ENSMUSG00000073878
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 CCL21ENSG00000137077Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
P86792 / P86793 / Gm21541 / predicted gene, 21541 / CCL21* / O00585* / C-C motif chemokine ligand 21*ENSMUSG00000094065100
Ccl21b / P86793 / P86792 / C-C motif chemokine 21b / CCL21* / O00585* / C-C motif chemokine ligand 21*ENSMUSG00000095675100
P86792 / P86793 / Gm10591 / predicted gene 10591 / CCL21* / O00585* / C-C motif chemokine ligand 21*ENSMUSG00000096596100
P84444 / Ccl21a / C-C motif chemokine 21a / CCL21* / O00585* / C-C motif chemokine ligand 21*ENSMUSG0000009468699


Protein motifs (from Interpro)
Interpro ID Name
 IPR001811  Chemokine interleukin-8-like domain
 IPR030593  C-C motif chemokine 21
 IPR036048  Chemokine interleukin-8-like superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0002548 monocyte chemotaxis IBA
 biological_processGO:0006935 chemotaxis IEA
 biological_processGO:0006954 inflammatory response IBA
 biological_processGO:0006955 immune response IEA
 biological_processGO:0007186 G-protein coupled receptor signaling pathway IBA
 biological_processGO:0010469 regulation of signaling receptor activity IEA
 biological_processGO:0030593 neutrophil chemotaxis IBA
 biological_processGO:0030595 leukocyte chemotaxis ISO
 biological_processGO:0043547 positive regulation of GTPase activity IBA
 biological_processGO:0045638 negative regulation of myeloid cell differentiation ISO
 biological_processGO:0048247 lymphocyte chemotaxis IBA
 biological_processGO:0060326 cell chemotaxis IEA
 biological_processGO:0070098 chemokine-mediated signaling pathway IBA
 biological_processGO:0070374 positive regulation of ERK1 and ERK2 cascade IBA
 biological_processGO:0071346 cellular response to interferon-gamma IBA
 biological_processGO:0071347 cellular response to interleukin-1 IBA
 biological_processGO:0071356 cellular response to tumor necrosis factor IBA
 cellular_componentGO:0005576 extracellular region IEA
 cellular_componentGO:0005615 extracellular space IEA
 cellular_componentGO:0009897 external side of plasma membrane IDA
 molecular_functionGO:0005125 cytokine activity IEA
 molecular_functionGO:0008009 chemokine activity IBA
 molecular_functionGO:0031732 CCR7 chemokine receptor binding IEA
 molecular_functionGO:0042379 chemokine receptor binding ISO
 molecular_functionGO:0048020 CCR chemokine receptor binding IBA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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