| MP:0000819 | abnormal olfactory bulb morphology | "malformation or absence of the forebrain region that coordinates neuronal signaling involved in the perception of smell; it receives input from the sensory neurons and outputs to the olfactory cortex" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, Principles of Neural Science:ISBN 0-8385-8034-3, J:16461] |
Show
Allelic Composition: Adcy3tm1Drs/Adcy3tm1Drs,Omptm1Mom/Omp+
Genetic Background: involves: 129S2/SvPas * 129X1/SvJ * C57BL/6
Allelic Composition: Omptm1(tTA)Gogo/Omp+,Tg(tetO-Kcnj2,lacZ)1Gogo/?
Genetic Background: involves: 129 * C57BL/6 * CBA
Allelic Composition: Robo2tm1Rilm/Robo2tm1Rilm,Olfr73tm1.1Jfcl/?,Omptm1(cre)Jae/Omp+
Genetic Background: involves: 129 * 129S1/Sv
Allelic Composition: Robo2tm1Rilm/Robo2tm1Rilm,Olfr160tm4Mom/?,Omptm1(cre)Jae/Omp+
Genetic Background: involves: 129 * 129P2/OlaHsd * 129S1/Sv
Allelic Composition: Omptm1(tTA)Gogo/Omp+,Tg(tetO-APPSwInd)Dbo/0
Genetic Background: involves: 129 * C3H/HeJ * C57BL/6J
|
| MP:0001262 | decreased body weight | "lower than normal average weight " [J:61295] |
Show
Allelic Composition: Kitltm1.1Sjm/Kitltm2.1Sjm,Leprtm2(cre)Rck/Lepr+,Tg(Tek-cre)12Flv/0
Genetic Background: involves: 129S6/SvEvTac * C3H * C57BL/6 * C57BL/Ka * SJL
Allelic Composition: Slc24a4tm1.2Hazh/Slc24a4tm1.2Hazh,Omptm4(cre)Mom/Omp+
Genetic Background: involves: 129P2/OlaHsd * 129S4/SvJaeSor * 129S6/SvEvTac * C57BL/6
|
| MP:0001983 | abnormal olfactory system physiology | "abnormal function of the system relating to smell " [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator] |
Show
Allelic Composition: Prkdcscid/Prkdcscid,Tg(INS-Il10)#Sar/0
Genetic Background: NOD.Cg-Prkdcscid Tg(INS-Il10)#Sar
Allelic Composition: Slc24a4tm1.2Hazh/Slc24a4tm1.2Hazh,Omptm4(cre)Mom/Omp+
Genetic Background: involves: 129P2/OlaHsd * 129S4/SvJaeSor * 129S6/SvEvTac * C57BL/6
Allelic Composition: Gng13tm1Liqh/Gng13tm1Liqh,Omptm4(cre)Mom/Omp+
Genetic Background: involves: 129P2/OlaHsd * 129S4/SvJaeSor * C57BL/6
|
| MP:0002067 | abnormal sensory capabilities/reflexes/nociception | "inability or altered ability to respond to a sensory stimulus" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator] |
Show
Allelic Composition: Six1tm2.2Mair/Six1tm2.2Mair
Genetic Background: involves: C57BL/6NTac
Allelic Composition: Pgrmc1tm1.1Jjp/Pgrmc1tm1.1Jjp,Omptm1(cre)Jae/Omp+
Genetic Background: involves: 129S1/Sv
|
| MP:0002169 | no phenotype detected | "normal, viable and fertile appearance and behavior; indistinguishable from controls" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator] |
Show
Allelic Composition: Chrna4tm1.2Tmcg/Chrna4tm1.2Tmcg
Genetic Background: involves: 129S/SvEv * 129S1/Sv * C57BL/6
|
| MP:0002229 | CNS neurodegeneration | "a retrogressive impairment of function or destruction of neural tissue" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8, csmith:Cynthia L. Smith , Mouse Genome Informatics Curator] |
Show
Allelic Composition: Casz1tm1.1Flc/Casz1tm1.1Flc,Isl1tm1(cre)Tmj/Isl1+
Genetic Background: involves: 129P2/OlaHsd * 129X1/SvJ * C57BL/6 * C57BL/6J * SJL
|
| MP:0002741 | small olfactory bulb | "reduced size of the forebrain region that coordinates neuronal signaling involved in the perception of smell; it receives input from the sensory neurons and outputs to the olfactory cortex" [J:79871] |
Show
Allelic Composition: Prkdcscid/Prkdcscid,Tg(INS-Il10)#Sar/0
Genetic Background: NOD.Cg-Prkdcscid Tg(INS-Il10)#Sar
Allelic Composition: Omptm1(tTA)Gogo/Omp+,Tg(tetO-APPSwInd)Dbo/0
Genetic Background: involves: 129 * C3H/HeJ * C57BL/6J
Allelic Composition: Omptm4(cre)Mom/Omp+,Ric8btm1c(EUCOMM)Hmgu/Ric8btm1c(EUCOMM)Hmgu
Genetic Background: involves: 129P2/OlaHsd * C57BL/6 * C57BL/6N * SJL
|
| MP:0003203 | increased neuron apoptosis | "increase in the number of neurons undergoing programmed cell death" [RGD:Rat Genome Database submission] |
Show
Allelic Composition: Omptm4(cre)Mom/Omp+,Ric8btm1c(EUCOMM)Hmgu/Ric8btm1c(EUCOMM)Hmgu
Genetic Background: involves: 129P2/OlaHsd * C57BL/6 * C57BL/6N * SJL
|
| MP:0005236 | abnormal olfactory nerve morphology | "anomalous structure of the first cranial nerve, which conveys the sense of smell" [MeSH:National Library of Medicine - Medical Subject Headings , 2003] |
Show
Allelic Composition: Adcy3tm1Drs/Adcy3tm1Drs,Omptm1Mom/Omp+
Genetic Background: involves: 129S2/SvPas * 129X1/SvJ * C57BL/6
Allelic Composition: Bdnftm2(BDNF)Gogo/Bdnf+,Omptm1(tTA)Gogo/Omp+,Tg(tetO-tetX,lacZ)2Gogo/?
Genetic Background: involves: 129S/SvEv
Allelic Composition: Ngfrtm1Jae/Ngfrtm1Jae,Omptm1(tTA)Gogo/Omp+,Tg(tetO-tetX,lacZ)2Gogo/?
Genetic Background: involves: 129S4/SvJae * C57BL/6
Allelic Composition: Ngfrtm1Jae/Ngfr+,Omptm1(tTA)Gogo/Omp+,Tg(tetO-tetX,lacZ)2Gogo/?
Genetic Background: involves: 129S4/SvJae * C57BL/6
Allelic Composition: Ngfrtm1Jae/Ngfrtm1Jae,Omptm1(tTA)Gogo/Omp+,Tg(tetO-tetX,lacZ)1Gogo/?
Genetic Background: involves: 129S4/SvJae * C57BL/6
Allelic Composition: Omptm1(tTA)Gogo/Omp+,Tg(tetO-tetX,lacZ)2Gogo/?
Genetic Background: Not Specified
Allelic Composition: Omptm1(tTA)Gogo/Omp+,Tg(tetO-tetX,lacZ)1Gogo/?
Genetic Background: involves: 129
Allelic Composition: Omptm1(tTA)Gogo/Omp+,Tg(tetO-Kcnj2,lacZ)1Gogo/?
Genetic Background: involves: 129 * C57BL/6 * CBA
Allelic Composition: Olfr17tm6Rax/Olfr17tm6Rax,Omptm1(tTA)Gogo/Omp+,Tg(tetO-Kcnj2,lacZ)1Gogo/?
Genetic Background: involves: 129S1/Sv * C57BL/6 * CBA
Allelic Composition: Olfr1507tm2Rax/Olfr1507+,Omptm1(tTA)Gogo/Omp+,Tg(tetO-Kcnj2,lacZ)1Gogo/?
Genetic Background: involves: 129P2/OlaHsd * C57BL/6 * CBA
|
| MP:0005499 | abnormal olfactory system morphology | "anomalous structure of the organs involved in smell" [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator] |
Show
Allelic Composition: Gng13tm1Liqh/Gng13tm1Liqh,Omptm4(cre)Mom/Omp+
Genetic Background: involves: 129P2/OlaHsd * 129S4/SvJaeSor * C57BL/6
|
| MP:0005584 | abnormal enzyme/coenzyme activity | "altered ability of any of these proteins, or their cofactors, to act as catalysts to induce chemical changes in other substances" [Stedman s Medical Dictionary:ISBN 0-683-40008-8] |
Show
Allelic Composition: Prkdcscid/Prkdcscid,Tg(INS-Il10)#Sar/0
Genetic Background: NOD.Cg-Prkdcscid Tg(INS-Il10)#Sar
|
| MP:0006092 | abnormal olfactory neuron morphology | "malformation in the neurons that are activated by specific odorants" [smb:Susan M Bello, Mouse Genome Informatics Curator, J:92950] |
Show
Allelic Composition: Ebf2tm2.1(Zfp423)Reed/Ebf2+
Genetic Background: Not Specified
Allelic Composition: Ebf2tm2(Zfp423)Reed/Ebf2+,Omptm4(cre)Mom/Omp+
Genetic Background: involves: 129P2/OlaHsd
Allelic Composition: Omptm1Mom/Omp+,Zfp423tm1Reed/Zfp423tm1Reed
Genetic Background: involves: 129S2/SvPas
Allelic Composition: Ebf2tm2(Zfp423)Reed/Ebf2+,Omptm4(cre)Mom/Omp+
Genetic Background: involves: 129 * 129P2/OlaHsd * C57BL/10J
Allelic Composition: Omptm1(tTA)Gogo/Omp+,Tg(tetO-APPSwInd)Dbo/0
Genetic Background: involves: 129 * C3H/HeJ * C57BL/6J
Allelic Composition: Omptm4(cre)Mom/Omp+,Ric8btm1c(EUCOMM)Hmgu/Ric8btm1c(EUCOMM)Hmgu
Genetic Background: involves: 129P2/OlaHsd * C57BL/6 * C57BL/6N * SJL
|
| MP:0008544 | impaired olfaction | "reduced ability to detect odors" [MGI:smb "Susan M. Bello, Mouse Genome Informatics Curator"] |
Show
Allelic Composition: Slc24a4tm1.2Hazh/Slc24a4tm1.2Hazh,Omptm4(cre)Mom/Omp+
Genetic Background: involves: 129P2/OlaHsd * 129S4/SvJaeSor * 129S6/SvEvTac * C57BL/6
Allelic Composition: Gng13tm1Liqh/Gng13tm1Liqh,Omptm4(cre)Mom/Omp+
Genetic Background: involves: 129P2/OlaHsd * 129S4/SvJaeSor * C57BL/6
Allelic Composition: Omptm1(tTA)Gogo/Omp+,Tg(tetO-APPSwInd)Dbo/0
Genetic Background: involves: 129 * C3H/HeJ * C57BL/6J
Allelic Composition: Omptm1(tTA)Gogo/Omptm2(spH)Mom,Tg(tetO-APPSwInd)Dbo/0
Genetic Background: involves: 129 * 129P2/OlaHsd * C3H/HeJ * C57BL/6J
Allelic Composition: Cfap69tm1c(KOMP)Wtsi/Cfap69tm1c(KOMP)Wtsi,Omptm4(cre)Mom/Omp+
Genetic Background: involves: 129P2/OlaHsd * 129S4/SvJaeSor * C57BL/6N
Allelic Composition: Omptm4(cre)Mom/Omp+,Ric8btm1c(EUCOMM)Hmgu/Ric8btm1c(EUCOMM)Hmgu
Genetic Background: involves: 129P2/OlaHsd * C57BL/6 * C57BL/6N * SJL
|
| MP:0008571 | abnormal synaptic bouton morphology | "any structural anomaly of the knoblike enlargements along the course of axons, or more commonly at the distal terminations of axons which are specialized for the release of neurotransmitters" [MESH:A08.663.542.145.750] |
Show
Allelic Composition: Omptm1(tTA)Gogo/Omp+,Tg(tetO-APPSwInd)Dbo/0
Genetic Background: involves: 129 * C3H/HeJ * C57BL/6J
|
| MP:0008770 | decreased survivor rate | "a smaller percentage of organisms than expected survive to adulthood and have a lifespan similar to controls" [MGI:llw2 "Linda Washburn, Mouse Genome Informatics Curator"] |
Show
Allelic Composition: Gng13tm1Liqh/Gng13tm1Liqh,Omptm4(cre)Mom/Omp+
Genetic Background: involves: 129P2/OlaHsd * 129S4/SvJaeSor * C57BL/6
Allelic Composition: Omptm4(cre)Mom/Omp+,Ric8btm1c(EUCOMM)Hmgu/Ric8btm1c(EUCOMM)Hmgu
Genetic Background: involves: 129P2/OlaHsd * C57BL/6 * C57BL/6N * SJL
|
| MP:0008789 | abnormal olfactory epithelium morphology | "any structural anomaly in the epithelial cells that line the interior of the nose" [MGI:smb "Susan M. Bello, Mouse Genome Informatics Curator"] |
Show
Allelic Composition: Ebf2tm2(Zfp423)Reed/Ebf2+,Omptm4(cre)Mom/Omp+
Genetic Background: involves: 129 * 129P2/OlaHsd * C57BL/10J
Allelic Composition: Omptm1(tTA)Gogo/Omp+,Tg(tetO-APPSwInd)Dbo/0
Genetic Background: involves: 129 * C3H/HeJ * C57BL/6J
|
| MP:0009946 | abnormal olfactory bulb layer morphology | "any structural anomaly of the laminar structure of the forebrain region that coordinates neuronal signaling involved in the perception of smell" [ISBN:0-683-40008-8 "Stedman s Medical Dictionary, 27th edition", MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"] |
Show
Allelic Composition: Omptm1(tTA)Gogo/Omptm2(spH)Mom,Tg(tetO-APPSwInd)Dbo/0
Genetic Background: involves: 129 * 129P2/OlaHsd * C3H/HeJ * C57BL/6J
|
| MP:0009948 | abnormal olfactory bulb glomerular layer morphology | |
Show
Allelic Composition: Omptm1(tTA)Gogo/Omp+,Tg(tetO-APPSwInd)Dbo/0
Genetic Background: involves: 129 * C3H/HeJ * C57BL/6J
Allelic Composition: Omptm4(cre)Mom/Omp+,Ric8btm1c(EUCOMM)Hmgu/Ric8btm1c(EUCOMM)Hmgu
Genetic Background: involves: 129P2/OlaHsd * C57BL/6 * C57BL/6N * SJL
|
| MP:0010055 | abnormal sensory neuron physiology | "any functional anomaly of cells that innervate an effector (muscle or glandular) tissue and are responsible for transmission of sensory impulses" [ISBN:0-683-40008-8 "Stedman s Medical Dictionary, 27th edition"] |
Show
Allelic Composition: Slc24a4tm1.2Hazh/Slc24a4tm1.2Hazh,Omptm4(cre)Mom/Omp+
Genetic Background: involves: 129P2/OlaHsd * 129S4/SvJaeSor * 129S6/SvEvTac * C57BL/6
|
| MP:0010057 | abnormal olfactory bulb outer nerve layer moprhology | "any strucutral anomaly of the outerpost layer of the olfactory bulb; consists primarily of olfactory afferent axons and ensheathing glia" [PMID:12533617] |
Show
Allelic Composition: Omptm1(tTA)Gogo/Omp+,Tg(tetO-APPSwInd)Dbo/0
Genetic Background: involves: 129 * C3H/HeJ * C57BL/6J
|
| MP:0011086 | partial postnatal lethality | "the appearance of lower than Mendelian ratios of organisms of a given genotype due to death of some, but not all of the organisms anytime between the neonatal period and weaning age (Mus: P1 to approximately 3 weeks of age)" [MGI:csmith] |
Show
Allelic Composition: Omptm4(cre)Mom/Omp+,Ric8btm1c(EUCOMM)Hmgu/Ric8btm1c(EUCOMM)Hmgu
Genetic Background: involves: 129P2/OlaHsd * C57BL/6 * C57BL/6N * SJL
|
| MP:0011677 | abnormal olfactory sensory neuron physiology | "any functional anomaly of cells that innervate the olfactory epithelium and are responsible for receiving and transmitting odorant signals" [MGI:csmith] |
Show
Allelic Composition: Gng13tm1Liqh/Gng13tm1Liqh,Omptm4(cre)Mom/Omp+
Genetic Background: involves: 129P2/OlaHsd * 129S4/SvJaeSor * C57BL/6
Allelic Composition: Omptm1(tTA)Gogo/Omp+,Tg(tetO-APPSwInd)Dbo/0
Genetic Background: involves: 129 * C3H/HeJ * C57BL/6J
Allelic Composition: Cfap69tm1c(KOMP)Wtsi/Cfap69tm1c(KOMP)Wtsi,Omptm4(cre)Mom/Omp+
Genetic Background: involves: 129P2/OlaHsd * 129S4/SvJaeSor * C57BL/6N
Allelic Composition: Omptm4(cre)Mom/Omp+,Ric8btm1c(EUCOMM)Hmgu/Ric8btm1c(EUCOMM)Hmgu
Genetic Background: involves: 129P2/OlaHsd * C57BL/6 * C57BL/6N * SJL
|
| MP:0011827 | impaired neuron differentiation | "decreased production of or inability to produce the mature cells of the nervous system that receive, conduct, and transmit impulses" [MGI:csmith] |
Show
Allelic Composition: Ebf2tm2(Zfp423)Reed/Ebf2+,Omptm4(cre)Mom/Omp+
Genetic Background: involves: 129 * 129P2/OlaHsd * C57BL/10J
|
| MP:0012020 | abnormal olfactory epithelium physiology | "any functional anomaly in the epithelial cells that line the interior of the nose" [MGI:smb] |
Show
Allelic Composition: Omptm4(cre)Mom/Omp+,Ric8btm1c(EUCOMM)Hmgu/Ric8btm1c(EUCOMM)Hmgu
Genetic Background: involves: 129P2/OlaHsd * C57BL/6 * C57BL/6N * SJL
|
| MP:0020348 | decreased olfactory sensory neuron number | "decreased number of the neurons in the olfactory epithelium that are activated by specific odorants" [MGI:mberry, ORCID: orcid.org/0000-0003-4606-0597] |
Show
Allelic Composition: Omptm1(tTA)Gogo/Omp+,Tg(tetO-APPSwInd)Dbo/0
Genetic Background: involves: 129 * C3H/HeJ * C57BL/6J
Allelic Composition: Olfr17tm1Mom/Olfr17+,Omptm1(tTA)Gogo/Omp+,Tg(tetO-APPSwInd)Dbo/0
Genetic Background: involves: 129 * 129P2/OlaHsd * C3H/HeJ * C57BL/6J
Allelic Composition: Olfr151tm25Mom/Olfr151+,Omptm1(tTA)Gogo/Omp+,Tg(tetO-APPSwInd)Dbo/0
Genetic Background: involves: 129 * C3H/HeJ * C57BL/6J
Allelic Composition: Omptm4(cre)Mom/Omp+,Ric8btm1c(EUCOMM)Hmgu/Ric8btm1c(EUCOMM)Hmgu
Genetic Background: involves: 129P2/OlaHsd * C57BL/6 * C57BL/6N * SJL
|
