ENSMUSG00000078762


Mus musculus
centrosomeHaus5hauscomplexmicrotubulemitoticsubunitcellcyclespindlelosscentrosomesrecruitmentproteinsmetazoaaugmin-likeassemblydivisioncytoplasmorganizingcentercytoskeletonmolecularfunctionregulationplkactivitygmtransitionnlp

Features
Gene ID: ENSMUSG00000078762
  
Biological name :Haus5
  
Synonyms : Haus5 / HAUS augmin-like complex subunit 5 / Q9D786
  
Possible biological names infered from orthology : O94927
  
Species: Mus musculus
  
Chr. number: 7
Strand: -1
Band: B1
Gene start: 30653711
Gene end: 30664994
  
Corresponding Affymetrix probe sets: 10352356 (MoGene1.0st)   10562084 (MoGene1.0st)   1452715_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000019697
Ensembl peptide - ENSMUSP00000121739
NCBI entrez gene - 71909     See in Manteia.
MGI - MGI:1919159
RefSeq - NM_027999
RefSeq Peptide - NP_082275
swissprot - Q9D786
Ensembl - ENSMUSG00000078762
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 haus5ENSDARG00000019156Danio rerio
 HAUS5ENSG00000249115Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
No match


Protein motifs (from Interpro)
Interpro ID Name
 IPR026215  HAUS complex subunit 5, metazoa
 IPR029131  HAUS augmin-like complex subunit 5


Gene Ontology (GO)
cell cyclecellular component organizationmicrotubule-based processcellular component biogenesiscell divisioncell cyclecellular component organizationmicrotubule-based processcellular component biogenesiscell divisioncell cyclecellular component organizationmicrotubule-based processcellular component biogenesiscell divisioncell cyclecellular component organizationmicrotubule-based processcellular component biogenesiscell divisioncell cyclecellular component organizationmicrotubule-based processcellular component biogenesiscell divisioncell cyclecellular component organizationmicrotubule-based processcellular component biogenesiscell divisioncell cyclecellular component organizationmicrotubule-based processcellular component biogenesiscell divisioncell cyclecellular component organizationmicrotubule-based processcellular component biogenesiscell divisioncell cyclecellular component organizationmicrotubule-based processcellular component biogenesiscell divisioncell cyclecellular component organizationmicrotubule-based processcellular component biogenesiscell divisioncell cyclecell cyclecellular component organizatcellular component organizationmicrotubule-based processmicrotubule-based processcellular component biogenesicellular component biogenesiscell divisioncell division
cellorganellesupramolecular complexprotein-containing complexcellorganellesupramolecular complexprotein-containing complexcellorganellesupramolecular complexprotein-containing complexcellorganellesupramolecular complexprotein-containing complexcellorganellesupramolecular complexprotein-containing complexcellorganellesupramolecular complexprotein-containing complexcellorganellesupramolecular complexprotein-containing complexcellorganellesupramolecular complexprotein-containing complexcellorganellesupramolecular complexprotein-containing complexcellorganellesupramolecular complexprotein-containing complexcellcellorganelleorganellesupramolecular complexsupramolecular complexprotein-containing complexprotein-containing complex
TypeGO IDTermEv.Code
 biological_processGO:0007049 cell cycle IEA
 biological_processGO:0007098 centrosome cycle ISS
 biological_processGO:0051225 spindle assembly ISS
 biological_processGO:0051301 cell division IEA
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0005813 centrosome IEA
 cellular_componentGO:0005815 microtubule organizing center IEA
 cellular_componentGO:0005819 spindle IEA
 cellular_componentGO:0005856 cytoskeleton IEA
 cellular_componentGO:0005874 microtubule IEA
 cellular_componentGO:0070652 HAUS complex ISS
 molecular_functionGO:0003674 molecular_function ND


Pathways (from Reactome)
Pathway description
Regulation of PLK1 Activity at G2/M Transition
Loss of Nlp from mitotic centrosomes
Recruitment of mitotic centrosome proteins and complexes
Loss of proteins required for interphase microtubule organization from the centrosome
Recruitment of NuMA to mitotic centrosomes
Anchoring of the basal body to the plasma membrane
AURKA Activation by TPX2


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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