ENSMUSG00000079707


Mus musculus

Features
Gene ID: ENSMUSG00000079707
  
Biological name :Tcte3
  
Synonyms : P11985 / t-complex-associated testis expressed 3 / Tcte3
  
Possible biological names infered from orthology : Q8IZS6
  
Species: Mus musculus
  
Chr. number: 17
Strand: -1
Band: A2
Gene start: 15027157
Gene end: 15041559
  
Corresponding Affymetrix probe sets: 10448016 (MoGene1.0st)   10448023 (MoGene1.0st)   1421682_a_at (Mouse Genome 430 2.0 Array)   1421683_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000036704
Ensembl peptide - ENSMUSP00000095010
NCBI entrez gene - 21647     See in Manteia.
MGI - MGI:98642
RefSeq - NM_011560
RefSeq - NM_198104
RefSeq Peptide - NP_035690
RefSeq Peptide - NP_932772
swissprot - P11985
swissprot - A0A0R4J284
Ensembl - ENSMUSG00000079707
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 TCTE3ENSGALG00000011189Gallus gallus
 TCTE3ENSG00000184786Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Gm3448 / P11985 / Tctex1 domain-containing protein 3 / TCTE3* / Q8IZS6* / t-complex-associated-testis-expressed 3*ENSMUSG0000007971099
Q8CDY7 / Tctex1d4 / Tctex1 domain-containing protein 4 / Q5JR98* / Tctex1 domain containing 4*ENSMUSG0000004767123
Q9CQ66 / Tctex1d2 / Tctex1 domain containing 2 / Q8WW35* / AC069257.3*ENSMUSG0000001407516
Q9D5I4 / Tctex1d1 / Tctex1 domain containing 1 / Q8N7M0*ENSMUSG0000002852316


Protein motifs (from Interpro)
Interpro ID Name
 IPR005334  Tctex-1


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0007018 microtubule-based movement IDA
 biological_processGO:0008150 biological_process ND
 cellular_componentGO:0005575 cellular_component ND
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0005856 cytoskeleton IEA
 cellular_componentGO:0005868 cytoplasmic dynein complex IDA
 cellular_componentGO:0005874 microtubule IEA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0019898 extrinsic component of membrane IDA
 cellular_componentGO:0030286 dynein complex IEA
 cellular_componentGO:0036126 sperm flagellum IDA
 molecular_functionGO:0003674 molecular_function ND
 molecular_functionGO:0003774 motor activity IEA
 molecular_functionGO:0005515 protein binding IPI


Pathways (from Reactome)
Pathway description
Intraflagellar transport


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0001155 arrest of spermatogenesis "block of the process by which spermatogonial stem cells divide and differentiate into spermatozoa" [J:62271]
Show

Allelic Composition: Traf3ip2adjm/Traf3ip2adjm
Genetic Background: AK.KOR-Traf3ip2adjm

 MP:0001925 male infertility "inability of male to produce live offspring" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:60409]
Show

Allelic Composition: Traf3ip2adjm/Traf3ip2adjm
Genetic Background: AK.KOR-Traf3ip2adjm

 MP:0002675 asthenozoospermia "loss or reduction of the mobility of the spermatozoa, frequently associated with infertility" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8, pvb:Pierre Vanden Borre , Mouse Genome Informatics Curator]
Show

Allelic Composition: Traf3ip2adjm/Traf3ip2adjm
Genetic Background: AK.KOR-Traf3ip2adjm

 MP:0002687 oligozoospermia "reduced concentration of spermatozoa " [pvb:Pierre Vanden Borre , Mouse Genome Informatics Curator, J:57312]
Show

Allelic Composition: Traf3ip2adjm/Traf3ip2adjm
Genetic Background: AK.KOR-Traf3ip2adjm

 MP:0004852 decreased testis weight "reduced average weight of the male reproductive glands" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]
Show

Allelic Composition: Traf3ip2adjm/Traf3ip2adjm
Genetic Background: AK.KOR-Traf3ip2adjm

 MP:0008280 male germ cell apoptosis "presence of male germs cells that undergo programmed cell death" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]
Show

Allelic Composition: Traf3ip2adjm/Traf3ip2adjm
Genetic Background: AK.KOR-Traf3ip2adjm

 MP:0008892 abnormal sperm flagellum "any strucutral anomaly of the whiplike posterior filiform portion of the spermatozoon that provides sperm motility" [MESH:A05.360.490.890.840]
Show

Allelic Composition: Traf3ip2adjm/Traf3ip2adjm
Genetic Background: AK.KOR-Traf3ip2adjm

 MP:0009230 abnormal sperm head morphology "any structural abnormality of the head segment of the sperm cell which contains the nucleus with densely coiled chromatin fibers, and is surrounded anteriorly by the acrosome which contains enzymes used for penetrating the female egg" [MGI:anna "Anna V. Anagnostopoulos, Mouse Genome Informatics Curator"]
Show

Allelic Composition: Traf3ip2adjm/Traf3ip2adjm
Genetic Background: AK.KOR-Traf3ip2adjm

 MP:0009839 multiflagellated sperm "presence of more than one sperm flagellum, displaying either one common origin from the sperm head or multiple origins from the same sperm head" [MGI:anna "Anna V. Anagnostopoulos, Mouse Genome Informatics Curator"]
Show

Allelic Composition: Traf3ip2adjm/Traf3ip2adjm
Genetic Background: AK.KOR-Traf3ip2adjm

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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