ENSMUSG00000094638


Mus musculus

Features
Gene ID: ENSMUSG00000094638
  
Biological name :Gm21972
  
Synonyms : Gm21972
  
Possible biological names infered from orthology : proteasome 26S subunit, non-ATPase 1 / PSMD1 / Q99460
  
Species: Mus musculus
  
Chr. number: 1
Strand: 1
Band: C5
Gene start: 86133637
Gene end: 86162788
  
Corresponding Affymetrix probe sets:
  
Cross references: Ensembl peptide - ENSMUSP00000136581
MGI - MGI:5439441
swissprot - J3QN38
Ensembl - ENSMUSG00000094638
  
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 psmd1ENSDARG00000003189Danio rerio
 PSMD1ENSGALG00000007664Gallus gallus
 PSMD1ENSG00000173692Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Psmd1 / Q3TXS7 / proteasome (prosome, macropain) 26S subunit, non-ATPase, 1 / Q99460* / proteasome 26S subunit, non-ATPase 1*ENSMUSG0000002622999


Protein motifs (from Interpro)
Interpro ID Name
No match


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0043161 proteasome-mediated ubiquitin-dependent protein catabolic process IBA
 biological_processGO:0050790 regulation of catalytic activity IEA
 cellular_componentGO:0005634 nucleus IBA
 cellular_componentGO:0008540 proteasome regulatory particle, base subcomplex IBA
 cellular_componentGO:0034515 proteasome storage granule IBA
 molecular_functionGO:0004175 endopeptidase activity IBA
 molecular_functionGO:0030234 enzyme regulator activity IEA


Pathways (from Reactome)
Pathway description
AUF1 (hnRNP D0) binds and destabilizes mRNA
ABC-family proteins mediated transport
Antigen processing: Ubiquitination & Proteasome degradation
Activation of NF-kappaB in B cells
Asymmetric localization of PCP proteins
CDK-mediated phosphorylation and removal of Cdc6
CLEC7A (Dectin-1) signaling
Degradation of DVL
Degradation of GLI1 by the proteasome
Cross-presentation of soluble exogenous antigens (endosomes)
Degradation of beta-catenin by the destruction complex
FBXL7 down-regulates AURKA during mitotic entry and in early mitosis
Downstream TCR signaling
GLI3 is processed to GLI3R by the proteasome
Hedgehog on state
Interleukin-1 signaling
MAPK6/MAPK4 signaling
Neddylation
Orc1 removal from chromatin
Neutrophil degranulation
Regulation of PTEN stability and activity
Regulation of ornithine decarboxylase (ODC)
Regulation of RUNX2 expression and activity
Regulation of RAS by GAPs
SCF(Skp2)-mediated degradation of p27/p21
Regulation of RUNX3 expression and activity
TNFR2 non-canonical NF-kB pathway
Ub-specific processing proteases
Ubiquitin Mediated Degradation of Phosphorylated Cdc25A
UCH proteinases
Ubiquitin-dependent degradation of Cyclin D1
Separation of Sister Chromatids
NIK-->noncanonical NF-kB signaling
APC/C:Cdc20 mediated degradation of Securin
Autodegradation of the E3 ubiquitin ligase COP1
SCF-beta-TrCP mediated degradation of Emi1
Autodegradation of Cdh1 by Cdh1:APC/C
CDT1 association with the CDC6:ORC:origin complex
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha
FCERI mediated NF-kB activation
Hedgehog ligand biogenesis
The role of GTSE1 in G2/M progression after G2 checkpoint
G2/M Checkpoints
RUNX1 regulates transcription of genes involved in differentiation of HSCs
Dectin-1 mediated noncanonical NF-kB signaling
Degradation of AXIN
Cdc20:Phospho-APC/C mediated degradation of Cyclin A
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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