ENSMUSG00000094985


Mus musculus

Features
Gene ID: ENSMUSG00000094985
  
Biological name :Topaz1
  
Synonyms : E5FYH1 / Testis- and ovary-specific PAZ domain-containing protein 1 / Topaz1
  
Possible biological names infered from orthology : Q8N9V7 / testis and ovary specific PAZ domain containing 1
  
Species: Mus musculus
  
Chr. number: 9
Strand: 1
Band: F4
Gene start: 122747346
Gene end: 122802135
  
Corresponding Affymetrix probe sets: 10590464 (MoGene1.0st)   
  
Cross references: Ensembl peptide - ENSMUSP00000136304
NCBI entrez gene - 671232     See in Manteia.
MGI - MGI:3779933
RefSeq - NM_001199736
RefSeq Peptide - NP_001186665
swissprot - E5FYH1
Ensembl - ENSMUSG00000094985
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 topaz1ENSDARG00000099801Danio rerio
 Q8N9V7ENSG00000173769Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
No match


Protein motifs (from Interpro)
Interpro ID Name
 IPR029435  Protein TOPAZ1 domain


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006915 apoptotic process IMP
 biological_processGO:0007286 spermatid development IMP
 biological_processGO:0048137 spermatocyte division IMP
 biological_processGO:0098781 ncRNA transcription IMP
 biological_processGO:1901995 positive regulation of meiotic cell cycle phase transition IMP
 cellular_componentGO:0005575 cellular_component ND
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0005829 cytosol IEA
 molecular_functionGO:0003674 molecular_function ND
 molecular_functionGO:0046872 metal ion binding IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0001147 small testis "reduced size of the male reproductive glands" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:58959]
Show

Allelic Composition: Pou3f4sdl/Y
Genetic Background: C3HeB/FeJ-Pou3f4sdl

 MP:0001925 male infertility "inability of male to produce live offspring" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:60409]
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Allelic Composition: Pou3f4sdl/Y
Genetic Background: C3HeB/FeJ-Pou3f4sdl

 MP:0004852 decreased testis weight "reduced average weight of the male reproductive glands" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]
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Allelic Composition: Pou3f4sdl/Y
Genetic Background: C3HeB/FeJ-Pou3f4sdl

 MP:0005159 azoospermia "absence of living spermatozoa " [Stedman s Medical Dictionary:ISBN 0-683-40008-8]
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Allelic Composition: Pou3f4sdl/Y
Genetic Background: C3HeB/FeJ-Pou3f4sdl

 MP:0006362 abnormal male germ cell morphology "any structural anomaly of male germ cells whether they are undifferentiated or fully differentiated" [MGI:llw2 "Linda Washburn, Mouse Genome Informatics Curator"]
Show

Allelic Composition: Pou3f4sdl/Y
Genetic Background: C3HeB/FeJ-Pou3f4sdl

 MP:0008261 arrest of male meiosis "cessation of the progression of the process of nuclear division that results in sperm with one half the normal chromosome number of the original cell" [ISBN:0-683-40008-8 "Stedman s Medical Dictionary, 27th edition"]
Show

Allelic Composition: Pou3f4sdl/Y
Genetic Background: C3HeB/FeJ-Pou3f4sdl

 MP:0008280 male germ cell apoptosis "presence of male germs cells that undergo programmed cell death" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]
Show

Allelic Composition: Pou3f4sdl/Y
Genetic Background: C3HeB/FeJ-Pou3f4sdl

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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