ENSMUSG00000102252


Mus musculus

Features
Gene ID: ENSMUSG00000102252
  
Biological name :Snrpn
  
Synonyms : P63163 / small nuclear ribonucleoprotein N / Snrpn
  
Possible biological names infered from orthology : P63162 / small nuclear ribonucleoprotein polypeptide N
  
Species: Mus musculus
  
Chr. number: 7
Strand: -1
Band: B5
Gene start: 59982495
Gene end: 60140219
  
Corresponding Affymetrix probe sets: 10564211 (MoGene1.0st)   1415895_at (Mouse Genome 430 2.0 Array)   1415896_x_at (Mouse Genome 430 2.0 Array)   1421063_s_at (Mouse Genome 430 2.0 Array)   1432096_at (Mouse Genome 430 2.0 Array)   1435716_x_at (Mouse Genome 430 2.0 Array)   1441905_x_at (Mouse Genome 430 2.0 Array)   1460075_x_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000055941
Ensembl peptide - ENSMUSP00000096003
NCBI entrez gene - 20646     See in Manteia.
MGI - MGI:98347
RefSeq - NM_001082961
RefSeq - NM_001082962
RefSeq - NM_001349691
RefSeq - NM_013670
RefSeq Peptide - NP_038698
RefSeq Peptide - NP_001076431
RefSeq Peptide - NP_001076430
RefSeq Peptide - NP_001336619
RefSeq Peptide - NP_001336620
RefSeq Peptide - NP_001336621
RefSeq Peptide - NP_001336622
RefSeq Peptide - NP_001336623
RefSeq Peptide - NP_001336624
swissprot - P63163
swissprot - Q3UN87
Ensembl - ENSMUSG00000102252
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 snrpbENSDARG00000011125Danio rerio
 SNRPLENSGALG00000035421Gallus gallus
 SNRPNENSG00000128739Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Snrpb / P27048 / Small nuclear ribonucleoprotein-associated protein B / P14678* / small nuclear ribonucleoprotein polypeptides B and B1*ENSMUSG0000002740489


Protein motifs (from Interpro)
Interpro ID Name
 IPR001163  LSM domain, eukaryotic/archaea-type
 IPR010920  LSM domain superfamily
 IPR017131  Small ribonucleoprotein associated, SmB/SmN


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0000398 mRNA splicing, via spliceosome IBA
 biological_processGO:0009725 response to hormone IEA
 cellular_componentGO:0005634 nucleus TAS
 cellular_componentGO:0005654 nucleoplasm IEA
 cellular_componentGO:0005682 U5 snRNP IBA
 cellular_componentGO:0005685 U1 snRNP IEA
 cellular_componentGO:0005686 U2 snRNP IEA
 cellular_componentGO:0005687 U4 snRNP IBA
 cellular_componentGO:0005737 cytoplasm IBA
 cellular_componentGO:0046540 U4/U6 x U5 tri-snRNP complex IBA
 cellular_componentGO:0071004 U2-type prespliceosome IBA
 cellular_componentGO:0071013 catalytic step 2 spliceosome IBA
 molecular_functionGO:0003723 RNA binding IBA


Pathways (from Reactome)
Pathway description
mRNA Splicing - Major Pathway


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0000746 weakness "state of being infirm or less strong than littermates" [J:45400]
Show

Allelic Composition: Slc17a7tm1Edw/Slc17a7tm1Edw
Genetic Background: involves: 129X1/SvJ

 MP:0001260 increased body weight "greater than normal average weight " [J:33400]
Show

Allelic Composition: Snai1tm2.1Grid/Snai1tm2.1Grid
Genetic Background: involves: 129S1/Sv * C57BL/6J

 MP:0001262 decreased body weight "lower than normal average weight " [J:61295]
Show

Allelic Composition: Snai1tm2.1Grid/Snai1tm2.1Grid
Genetic Background: involves: 129S1/Sv * C57BL/6J

Allelic Composition: Snrpntm2Alb/Snrpn+
Genetic Background: involves: 129S7/SvEvBrd * C57BL/6J

 MP:0001264 increased body size "larger than average body weight, height and/or length of an organism compared to controls" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:33401]
Show

Allelic Composition: Snai1tm2.1Grid/Snai1tm2.1Grid
Genetic Background: involves: 129S1/Sv * C57BL/6J

 MP:0001265 reduced body size "smaller than average body weight, height and/or length of an organism compared to controls" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8, J:23170]
Show

Allelic Composition: Snrpntm2Cbr/Snrpntm1Kaj
Genetic Background: involves: 129S1/Sv * C57BL/6

 MP:0001388 abnormal stationary movement "altered ability or inability to change body posture or shift a body part" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]
Show

Allelic Composition: Slc17a7tm1Edw/Slc17a7tm1Edw
Genetic Background: involves: 129X1/SvJ

 MP:0001429 dehydration "excessive water loss from the body or from an organ or bodily part" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:50053]
Show

Allelic Composition: Slc17a7tm1Edw/Slc17a7tm1Edw
Genetic Background: involves: 129X1/SvJ

 MP:0001436 abnormal suckling behavior "reduced ability or inability to exert suction by the mouth, or atypical suckling pattern" [J:16461]
Show

Allelic Composition: Slc17a7tm1Edw/Slc17a7tm1Edw
Genetic Background: involves: 129X1/SvJ

 MP:0001732 postnatal growth retardation "slow or limited development after birth " [Stedman s Medical Dictionary:ISBN 0-683-40008-8]
Show

Allelic Composition: Snai1tm2.1Grid/Snai1tm2.1Grid
Genetic Background: involves: 129S1/Sv * C57BL/6J

Allelic Composition: Snrpntm2Cbr/Snrpn+
Genetic Background: involves: 129S1/Sv * C57BL/6

Allelic Composition: Snrpntm2Cbr/Snrpntm1Kaj
Genetic Background: involves: 129S1/Sv * C57BL/6

Allelic Composition: Snrpntm2Alb/Snrpn+
Genetic Background: involves: 129S7/SvEvBrd * C57BL/6J

 MP:0002082 postnatal lethality "premature death anytime after postnatal day 1 to weaning age (3 weeks)" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]
Show

Allelic Composition: Chd7Gt(S20-7E1)Sor/Chd7+
Genetic Background: either: (involves: 129S4/SvJae * C57BL/6J) or (involves: 129S1/SvImJ * 129S4/SvJae C57BL/6J)

 MP:0002169 no phenotype detected "normal, viable and fertile appearance and behavior; indistinguishable from controls" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]
Show

Allelic Composition: Snrpntm2Cbr/Snrpntm1Kaj
Genetic Background: involves: 129S1/Sv * C57BL/6

Allelic Composition: Snrpntm3Alb/Snrpntm3Alb
Genetic Background: either: (involves: 129S7/SvEvBrd) or (involves: 129S7/SvEvBrd * C57BL/6J)

Allelic Composition: Snrpntm3Alb/Snrpn+
Genetic Background: either: (involves: 129S7/SvEvBrd) or (involves: 129S7/SvEvBrd * C57BL/6J)

 MP:0003121 genomic imprinting "phenotype resulting from inactivation of specific loci during gametogenesis, but not encoded by the DNA itself" [llw2:Linda Washburn, Mouse Genome Informatics Curator, csmith:Cynthia L. Smith, Mouse Genome Informatics Curator]
Show

Allelic Composition: Snrpntm2Alb/Snrpn+
Genetic Background: involves: 129S7/SvEvBrd * C57BL/6J

Allelic Composition: Snrpntm4Alb/Snrpn+
Genetic Background: involves: 129S7/SvEvBrd * C57BL/6J

 MP:0003122 maternal imprinting "specific loci are inactivated during oogenesis and are not expressed in offspring" [llw2:Linda Washburn, Mouse Genome Informatics Curator, csmith:Cynthia L. Smith, Mouse Genome Informatics Curator]
Show

Allelic Composition: Snai1tm2.1Grid/Snai1tm2.1Grid
Genetic Background: involves: 129S1/Sv * C57BL/6J

Allelic Composition: Snrpntm2Cbr/Snrpn+
Genetic Background: involves: 129S1/Sv * C57BL/6

Allelic Composition: Snrpntm2Cbr/Snrpntm1Kaj
Genetic Background: involves: 129S1/Sv * C57BL/6

Allelic Composition: Snrpntm2Cbr/Snrpn+
Genetic Background: either: (involves: 129S1/Sv * C57BL/6J) or (involves: 129S1/Sv * BALB/c * C57BL/6J) or (involves: 129S1/Sv * C3H/HeJ * C57BL/6J) or (involves: 129S1/Sv * C57BL/6J * FVB/NJ)

Allelic Composition: Snrpntm2Cbr/Snrpn+
Genetic Background: either: B6.Cg-Snrpntm2Cbr or (involves: 129S1/Sv * C57BL/6J * DBA/2J)

 MP:0003787 abnormal imprinting "defect in the normal inactivation of specific loci during gametogenesis" [llw2:Linda Washburn , Mouse Genome Informatics Curator]
Show

Allelic Composition: Snai1tm2.1Grid/Snai1tm2.1Grid
Genetic Background: involves: 129S1/Sv * C57BL/6J

Allelic Composition: Arid4atm1Alb/Arid4atm1Alb,Snrpntm4Alb/Snrpn+
Genetic Background: involves: 129S7/SvEvBrd * C57BL/6

Allelic Composition: Snrpntm4Alb/Snrpntm4Alb
Genetic Background: involves: 129S7/SvEvBrd * C57BL/6

Allelic Composition: Arid4btm1Alb/Arid4b+,Snrpntm4Alb/Snrpn+
Genetic Background: involves: 129S7/SvEvBrd * C57BL/6

Allelic Composition: Rb1tm1Brd/Rb1+,Snrpntm4Alb/Snrpn+
Genetic Background: involves: 129S7/SvEvBrd * C57BL/6

 MP:0005560 decreased circulating glucose level "less than the normal concentration in the blood of this major monosaccharide of the body; it is an important energy source" [RGD:Rat Genome Database submission, cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator]
Show

Allelic Composition: Snrpntm2Cbr/Snrpn+
Genetic Background: involves: 129S1/Sv * C57BL/6

 MP:0008877 abnormal DNA methylation "any anomaly in the covalent transfer of a methyl group to either N-6 of adenine or C-5 or N-4 of cytosine of DNA" [GO:0006306]
Show

Allelic Composition: Arid4atm1Alb/Arid4atm1Alb,Snrpntm4Alb/Snrpn+
Genetic Background: involves: 129S7/SvEvBrd * C57BL/6

Allelic Composition: Snrpntm4Alb/Snrpntm4Alb
Genetic Background: involves: 129S7/SvEvBrd * C57BL/6

Allelic Composition: Arid4btm1Alb/Arid4b+,Snrpntm4Alb/Snrpn+
Genetic Background: involves: 129S7/SvEvBrd * C57BL/6

Allelic Composition: Rb1tm1Brd/Rb1+,Snrpntm4Alb/Snrpn+
Genetic Background: involves: 129S7/SvEvBrd * C57BL/6

Allelic Composition: Snrpntm5Alb/Snrpn+
Genetic Background: involves: 129S7/SvEvBrd * C57BL/6J

Allelic Composition: Snrpntm4Alb/Snrpn+
Genetic Background: involves: 129S7/SvEvBrd * C57BL/6J

Allelic Composition: Snrpntm2.1Kaj/Snrpn+,Alpltm1(cre)Nagy/Alpl+
Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6

 MP:0009546 absent gastric milk in neonates "failure of nursing offspring to ingest milk as indicated by stomach content" [MGI:llw2 "Linda Washburn, Mouse Genome Informatics Curator"]
Show

Allelic Composition: Snai1tm2.1Grid/Snai1tm2.1Grid
Genetic Background: involves: 129S1/Sv * C57BL/6J

Allelic Composition: Snrpntm2.1Kaj/Snrpn+,Alpltm1(cre)Nagy/Alpl+
Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6

 MP:0009674 decreased birth weight "reduction in average weight at birth compared to controls" [RGD:cur "Rat Genome Database submission"]
Show

Allelic Composition: Snrpntm2Cbr/Snrpn+
Genetic Background: involves: 129S1/Sv * C57BL/6

Allelic Composition: Snrpntm2.1Kaj/Snrpn+,Alpltm1(cre)Nagy/Alpl+
Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6

 MP:0010024 increased total body fat amount "greater than the normal total amount of connective tissue composed of fat cells within the entire body" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]
Show

Allelic Composition: Snai1tm2.1Grid/Snai1tm2.1Grid
Genetic Background: involves: 129S1/Sv * C57BL/6J

 MP:0011085 complete postnatal lethality "premature death anytime between the neonatal period and weaning age of all organisms of a given genotype in a population (Mus: P1 to approximately 3 weeks of age)" [MGI:csmith]
Show

Allelic Composition: Snrpntm2Cbr/Snrpn+
Genetic Background: involves: 129S1/Sv * C57BL/6

Allelic Composition: Snrpntm2Cbr/Snrpn+
Genetic Background: either: (involves: 129S1/Sv * C57BL/6J) or (involves: 129S1/Sv * BALB/c * C57BL/6J) or (involves: 129S1/Sv * C3H/HeJ * C57BL/6J) or (involves: 129S1/Sv * C57BL/6J * FVB/NJ)

Allelic Composition: Snrpntm2Cbr/Snrpn+
Genetic Background: either: B6.Cg-Snrpntm2Cbr or (involves: 129S1/Sv * C57BL/6J * DBA/2J)

Allelic Composition: Snrpntm2.1Kaj/Snrpn+,Alpltm1(cre)Nagy/Alpl+
Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6

 MP:0011086 partial postnatal lethality "the appearance of lower than Mendelian ratios of organisms of a given genotype due to death of some, but not all of the organisms anytime between the neonatal period and weaning age (Mus: P1 to approximately 3 weeks of age)" [MGI:csmith]
Show

Allelic Composition: Snai1tm2.1Grid/Snai1tm2.1Grid
Genetic Background: involves: 129S1/Sv * C57BL/6J

Allelic Composition: Snrpntm2Cbr/Snrpn+
Genetic Background: involves: 129S1/Sv * C57BL/6

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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