ENSMUSG00000104876


Mus musculus

Features
Gene ID: ENSMUSG00000104876
  
Biological name :Trdc
  
Synonyms : T cell receptor delta constant / Trdc
  
Possible biological names infered from orthology :
  
Species: Mus musculus
  
Chr. number: 14
Strand: 1
Band: C2
Gene start: 54142851
Gene end: 54148868
  
Corresponding Affymetrix probe sets: 1427655_a_at (Mouse Genome 430 2.0 Array)   1459400_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000142908
MGI - MGI:98612
swissprot - A0A0G2JEU3
Ensembl - ENSMUSG00000104876
  
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 TRDCENSG00000211829Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
No match


Protein motifs (from Interpro)
Interpro ID Name
No match


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006910 phagocytosis, recognition IBA
 biological_processGO:0006911 phagocytosis, engulfment IBA
 biological_processGO:0006958 complement activation, classical pathway IBA
 biological_processGO:0042742 defense response to bacterium IBA
 biological_processGO:0045087 innate immune response IBA
 biological_processGO:0050853 B cell receptor signaling pathway IBA
 biological_processGO:0050871 positive regulation of B cell activation IBA
 cellular_componentGO:0009897 external side of plasma membrane IDA
 cellular_componentGO:0042571 immunoglobulin complex, circulating IBA
 cellular_componentGO:0072562 blood microparticle IBA
 molecular_functionGO:0003823 antigen binding IBA
 molecular_functionGO:0034987 immunoglobulin receptor binding IBA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0000706 small thymus "reduced size of the thymus" [J:36561, cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator, J:31167]
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Allelic Composition: Rag1tm1.1Sadu/Rag1tm1.1Sadu,Trdctm1Mal/Trdctm1Mal,Gt(ROSA)26Sortm2(cre/ERT2)Brn/Gt(ROSA)26Sor+
Genetic Background: involves: 129P2/OlaHsd * BALB/c * C57BL/6

 MP:0002169 no phenotype detected "normal, viable and fertile appearance and behavior; indistinguishable from controls" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]
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Allelic Composition: Lattm4Mal/Lattm4Mal,Trdctm1Mal/Trdctm1Mal
Genetic Background: involves: 129P2/OlaHsd * C57BL/6

 MP:0002407 abnormal double-negative T cell "anomalous structure, development, or number of the subset of T cells found in the thymus that express neither CD4 nor CD8" [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator, Immunobiology , The Immune System in Health and Disease:ISBN 0-8153-1691-7]
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Allelic Composition: Lattm4Mal/Lattm4Mal,Trdctm1Mal/Trdctm1Mal
Genetic Background: involves: 129P2/OlaHsd * C57BL/6

Allelic Composition: Cd3etm1.1Lov/Cd3etm1.1Lov,Trdctm1Mal/Trdctm1Mal
Genetic Background: involves: C57BL/6

 MP:0008346 increased gamma-delta T cell number "greater number of immature or mature T cells expressing an gamma-delta T cell receptor complex" [CL:0000798, ISBN:0781735149]
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Allelic Composition: Rag1tm1.1Sadu/Rag1tm1.1Sadu,Trdctm1Mal/Trdctm1Mal,Gt(ROSA)26Sortm2(cre/ERT2)Brn/Gt(ROSA)26Sor+
Genetic Background: involves: 129P2/OlaHsd * BALB/c * C57BL/6

 MP:0008347 decreased gamma-delta T cell number "reduced number of immature or mature T cells expressing an gamma-delta T cell receptor complex" [CL:0000798, ISBN:0781735149]
Show

Allelic Composition: Rag1tm1.1Sadu/Rag1tm1.1Sadu,Trdctm1Mal/Trdctm1Mal,Gt(ROSA)26Sortm2(cre/ERT2)Brn/Gt(ROSA)26Sor+
Genetic Background: involves: 129P2/OlaHsd * BALB/c * C57BL/6

 MP:0008348 absent gamma-delta T cells "absence of immature or mature T cells expressing an gamma-delta T cell receptor complex" [CL:0000798, ISBN:0781735149]
Show

Allelic Composition: Rag1tm1.1Sadu/Rag1tm1.1Sadu,Trdctm1Mal/Trdctm1Mal,Gt(ROSA)26Sortm2(cre/ERT2)Brn/Gt(ROSA)26Sor+
Genetic Background: involves: 129P2/OlaHsd * BALB/c * C57BL/6

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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