10133


Homo sapiens (NCBI)

Features
Gene ID: 10133
  
Biological name :
  
Synonyms : ALS12|FIP2|GLC1E|HIP7|HYPL|NRP|TFIIIA-INTP / optineurin / OPTN
  
Possible biological names infered from orthology :
  
Species: Homo sapiens (NCBI)
  
Chr. number:
Strand:
Band:
Gene start:
Gene end:
  
Corresponding Affymetrix probe sets: 202073_at (Human Genome U133 Plus 2.0 Array)   202074_s_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: RefSeq - 20149572
RefSeq - 56549107
RefSeq - 56549109
RefSeq - 56549111
RefSeq - NC_000010.11
RefSeq - NG_012876.1
RefSeq - NP_001008212.1
RefSeq - NP_001008213.1
RefSeq - NP_001008214.1
RefSeq - NP_068815.2
RefSeq - NM_001008211.1
RefSeq - NM_001008212.1
RefSeq - NM_001008213.1
RefSeq - NM_021980.4
  
See co-cited genes in PubMed
Warning: Please see the Ensembl gene model ENSG00000123240 to get all the annotations available for this gene.


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0000086 G2/M transition of mitotic cell cycle TAS
 biological_processGO:0001920 negative regulation of receptor recycling IMP
 biological_processGO:0006914 autophagy IEA
 biological_processGO:0007030 Golgi organization IMP
 biological_processGO:0007165 signal transduction TAS
 biological_processGO:0008219 cell death TAS
 biological_processGO:0010508 positive regulation of autophagy IDA
 biological_processGO:0034067 protein localization to Golgi apparatus IMP
 biological_processGO:0034620 cellular response to unfolded protein IMP
 biological_processGO:0043001 Golgi to plasma membrane protein transport IMP
 biological_processGO:0043122 regulation of I-kappaB kinase/NF-kappaB signaling IBA
 biological_processGO:0043124 negative regulation of I-kappaB kinase/NF-kappaB signaling IEA
 biological_processGO:0045087 innate immune response IEA
 biological_processGO:0050829 defense response to Gram-negative bacterium IMP
 biological_processGO:0061734 parkin-mediated stimulation of mitophagy in response to mitochondrial depolarization IMP
 biological_processGO:0090161 Golgi ribbon formation IMP
 biological_processGO:1904417 positive regulation of xenophagy IMP
 cellular_componentGO:0000139 Golgi membrane TAS
 cellular_componentGO:0005634 nucleus IBA
 cellular_componentGO:0005654 nucleoplasm TAS
 cellular_componentGO:0005737 cytoplasm TAS
 cellular_componentGO:0005776 autophagosome IEA
 cellular_componentGO:0005794 Golgi apparatus IDA
 cellular_componentGO:0005802 trans-Golgi network IDA
 cellular_componentGO:0005829 cytosol TAS
 cellular_componentGO:0048471 perinuclear region of cytoplasm IEA
 cellular_componentGO:0055038 recycling endosome membrane TAS
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0008022 protein C-terminus binding IPI
 molecular_functionGO:0017137 Rab GTPase binding IPI
 molecular_functionGO:0030674 protein binding, bridging IPI
 molecular_functionGO:0031593 polyubiquitin modification-dependent protein binding IDA
 molecular_functionGO:0042802 identical protein binding IPI
 molecular_functionGO:0046872 metal ion binding IEA
 molecular_functionGO:0070530 K63-linked polyubiquitin modification-dependent protein binding IBA


Pathways (from Reactome)
Pathway description
No match


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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