10188


Homo sapiens (NCBI)

Features
Gene ID: 10188
  
Biological name :
  
Synonyms : ACK|ACK-1|ACK1|p21cdc42Hs / TNK2 / tyrosine kinase non receptor 2
  
Possible biological names infered from orthology :
  
Species: Homo sapiens (NCBI)
  
Chr. number:
Strand:
Band:
Gene start:
Gene end:
  
Corresponding Affymetrix probe sets: 1555557_a_at (Human Genome U133 Plus 2.0 Array)   1565783_at (Human Genome U133 Plus 2.0 Array)   203838_s_at (Human Genome U133 Plus 2.0 Array)   203839_s_at (Human Genome U133 Plus 2.0 Array)   216439_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: RefSeq - 58331191
RefSeq - 1034630621
RefSeq - 1034630623
RefSeq - 1034630625
RefSeq - 1370482914
RefSeq - 1370482916
RefSeq - 1370482918
RefSeq - 1370482920
RefSeq - 1370482922
RefSeq - 530375737
RefSeq - 530375741
RefSeq - 530375749
RefSeq - 530375751
RefSeq - 56549666
RefSeq - 1034630619
RefSeq - 767925456
RefSeq - 767925464
RefSeq - 767925467
RefSeq - 808688353
RefSeq - NC_000003.12
RefSeq - NG_029779.1
RefSeq - NP_001010938.1
RefSeq - NP_001294975.1
RefSeq - NP_005772.3
RefSeq - XP_005269325.1
RefSeq - XP_005269327.1
RefSeq - XP_005269331.1
RefSeq - XP_005269332.1
RefSeq - XP_011510619.1
RefSeq - XP_011510620.2
RefSeq - XP_011510622.1
RefSeq - XP_011510623.1
RefSeq - XP_016860997.1
RefSeq - XP_016860998.1
RefSeq - XP_016860999.1
RefSeq - XP_024309059.1
RefSeq - XP_024309060.1
RefSeq - XP_024309061.1
RefSeq - XP_024309062.1
RefSeq - XP_024309063.1
RefSeq - NM_001010938.1
RefSeq - NM_001308046.1
RefSeq - NM_005781.4
RefSeq - XM_024453293.1
RefSeq - XM_024453294.1
RefSeq - XM_024453295.1
RefSeq - XM_005269268.3
RefSeq - XM_005269270.3
RefSeq - XM_005269274.3
RefSeq - XM_005269275.3
RefSeq - XM_011512317.3
RefSeq - XM_011512318.2
RefSeq - XM_011512320.1
RefSeq - XM_011512321.2
RefSeq - XM_017005508.1
RefSeq - XM_017005509.1
RefSeq - XM_017005510.1
RefSeq - XM_024453291.1
RefSeq - XM_024453292.1
  
See co-cited genes in PubMed
Warning: Please see the Ensembl gene model ENSG00000061938 to get all the annotations available for this gene.


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006897 endocytosis IEA
 biological_processGO:0007166 cell surface receptor signaling pathway TAS
 biological_processGO:0007169 transmembrane receptor protein tyrosine kinase signaling pathway IBA
 biological_processGO:0007264 small GTPase mediated signal transduction TAS
 biological_processGO:0016310 phosphorylation IDA
 biological_processGO:0030154 cell differentiation IBA
 biological_processGO:0034260 negative regulation of GTPase activity IEA
 biological_processGO:0038083 peptidyl-tyrosine autophosphorylation IBA
 biological_processGO:0042127 regulation of cell proliferation IBA
 biological_processGO:0045087 innate immune response IBA
 biological_processGO:0050731 positive regulation of peptidyl-tyrosine phosphorylation IDA
 biological_processGO:2000369 regulation of clathrin-dependent endocytosis IDA
 cellular_componentGO:0005634 nucleus IDA
 cellular_componentGO:0005737 cytoplasm IDA
 cellular_componentGO:0005768 endosome ISS
 cellular_componentGO:0005886 plasma membrane IDA
 cellular_componentGO:0005905 clathrin-coated pit IDA
 cellular_componentGO:0005912 adherens junction IEA
 cellular_componentGO:0016020 membrane HDA
 cellular_componentGO:0030136 clathrin-coated vesicle IDA
 cellular_componentGO:0030659 cytoplasmic vesicle membrane IEA
 cellular_componentGO:0031234 extrinsic component of cytoplasmic side of plasma membrane IBA
 cellular_componentGO:0048471 perinuclear region of cytoplasm IEA
 cellular_componentGO:0070436 Grb2-EGFR complex IDA
 molecular_functionGO:0004674 protein serine/threonine kinase activity IEA
 molecular_functionGO:0004712 protein serine/threonine/tyrosine kinase activity IDA
 molecular_functionGO:0004713 protein tyrosine kinase activity IDA
 molecular_functionGO:0004715 non-membrane spanning protein tyrosine kinase activity IBA
 molecular_functionGO:0005095 GTPase inhibitor activity TAS
 molecular_functionGO:0005102 signaling receptor binding IBA
 molecular_functionGO:0005154 epidermal growth factor receptor binding IDA
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0005524 ATP binding IEA
 molecular_functionGO:0031625 ubiquitin protein ligase binding IPI
 molecular_functionGO:0042802 identical protein binding IPI
 molecular_functionGO:0046872 metal ion binding IEA
 molecular_functionGO:0050699 WW domain binding ISS


Pathways (from Reactome)
Pathway description
No match


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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