10266


Homo sapiens (NCBI)
receptorregulationproteinresponsesignalingpathwaymembraneadrenomedullinactivityangiogenesistransportg-proteincoupledassemblyvascularplasmacellamylincomplexvasculogenesisdevelopmentcellularstimulusjunctionendothelialbindinghypoxiasproutingcalciumion

Features
Gene ID: 10266
  
Biological name :
  
Synonyms : RAMP2 / receptor activity modifying protein 2
  
Possible biological names infered from orthology :
  
Species: Homo sapiens (NCBI)
  
Chr. number:
Strand:
Band:
Gene start:
Gene end:
  
Corresponding Affymetrix probe sets: 205779_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: RefSeq - 118572585
RefSeq - NC_000017.11
RefSeq - NP_005845.2
RefSeq - NM_005854.2
  
See co-cited genes in PubMed
Warning: Please see the Ensembl gene model ENSG00000131477 to get all the annotations available for this gene.


Gene Ontology (GO)
anatomical structure developmentcellular developmental processresponse to stressresponse to abiotic stimulusestablishment of localizationmacromolecule localizationcellular localizationcell communicationcellular response to stimulusmulti-multicellular organism processregulation of biological qualitysystem processorganic substance metabolic processcellular metabolic processresponse to endogenous stimulusresponse to chemicalcellular component organizationcellular component biogenesiscell deathanatomical structure developmentcellular developmental processresponse to stressresponse to abiotic stimulusestablishment of localizationmacromolecule localizationcellular localizationcell communicationcellular response to stimulusmulti-multicellular organism processregulation of biological qualitysystem processorganic substance metabolic processcellular metabolic processresponse to endogenous stimulusresponse to chemicalcellular component organizationcellular component biogenesiscell deathanatomical structure developmentcellular developmental processresponse to stressresponse to abiotic stimulusestablishment of localizationmacromolecule localizationcellular localizationcell communicationcellular response to stimulusmulti-multicellular organism processregulation of biological qualitysystem processorganic substance metabolic processcellular metabolic processresponse to endogenous stimulusresponse to chemicalcellular component organizationcellular component biogenesiscell deathanatomical structure developmentcellular developmental processresponse to stressresponse to abiotic stimulusestablishment of localizationmacromolecule localizationcellular localizationcell communicationcellular response to stimulusmulti-multicellular organism processregulation of biological qualitysystem processorganic substance metabolic processcellular metabolic processresponse to endogenous stimulusresponse to chemicalcellular component organizationcellular component biogenesiscell deathanatomical structure developmentcellular developmental processresponse to stressresponse to abiotic stimulusestablishment of localizationmacromolecule localizationcellular localizationcell communicationcellular response to stimulusmulti-multicellular organism processregulation of biological qualitysystem processorganic substance metabolic processcellular metabolic processresponse to endogenous stimulusresponse to chemicalcellular component organizationcellular component biogenesiscell deathanatomical structure developmentcellular developmental processresponse to stressresponse to abiotic stimulusestablishment of localizationmacromolecule localizationcellular localizationcell communicationcellular response to stimulusmulti-multicellular organism processregulation of biological qualitysystem processorganic substance metabolic processcellular metabolic processresponse to endogenous stimulusresponse to chemicalcellular component organizationcellular component biogenesiscell deathanatomical structure developmentcellular developmental processresponse to stressresponse to abiotic stimulusestablishment of localizationmacromolecule localizationcellular localizationcell communicationcellular response to stimulusmulti-multicellular organism processregulation of biological qualitysystem processorganic substance metabolic processcellular metabolic processresponse to endogenous stimulusresponse to chemicalcellular component organizationcellular component biogenesiscell deathanatomical structure developmentcellular developmental processresponse to stressresponse to abiotic stimulusestablishment of localizationmacromolecule localizationcellular localizationcell communicationcellular response to stimulusmulti-multicellular organism processregulation of biological qualitysystem processorganic substance metabolic processcellular metabolic processresponse to endogenous stimulusresponse to chemicalcellular component organizationcellular component biogenesiscell deathanatomical structure developmentcellular developmental processresponse to stressresponse to abiotic stimulusestablishment of localizationmacromolecule localizationcellular localizationcell communicationcellular response to stimulusmulti-multicellular organism processregulation of biological qualitysystem processorganic substance metabolic processcellular metabolic processresponse to endogenous stimulusresponse to chemicalcellular component organizationcellular component biogenesiscell deathanatomical structure developmentcellular developmental processresponse to stressresponse to abiotic stimulusestablishment of localizationmacromolecule localizationcellular localizationcell communicationcellular response to stimulusmulti-multicellular organism processregulation of biological qualitysystem processorganic substance metabolic processcellular metabolic processresponse to endogenous stimulusresponse to chemicalcellular component organizationcellular component biogenesiscell deathanatomianatomical structure developmentcellulacellular developmental processresponsresponse to stressresponsresponse to abiotic stimulusestabliestablishment of localizationmacromomacromolecule localizationcellulacellular localizationcell cocell communicationcellulacellular response to stimulusmulti-mmulti-multicellular organism processregulatregulation of biological qualitysystem system processorganicorganic substance metabolic processcellulacellular metabolic processresponsresponse to endogenous stimulusresponsresponse to chemicalcellulacellular component organizationcellulacellular component biogenesiscell decell death
signaling receptor activityprotein bindingprotein transporter activityhormone bindingamide bindingsignaling receptor activityprotein bindingprotein transporter activityhormone bindingamide bindingsignaling receptor activityprotein bindingprotein transporter activityhormone bindingamide bindingsignaling receptor activityprotein bindingprotein transporter activityhormone bindingamide bindingsignaling receptor activityprotein bindingprotein transporter activityhormone bindingamide bindingsignaling receptor activityprotein bindingprotein transporter activityhormone bindingamide bindingsignaling receptor activityprotein bindingprotein transporter activityhormone bindingamide bindingsignaling receptor activityprotein bindingprotein transporter activityhormone bindingamide bindingsignaling receptor activityprotein bindingprotein transporter activityhormone bindingamide bindingsignaling receptor activityprotein bindingprotein transporter activityhormone bindingamide bindingsignaling receptor activitysignaling receptor activityprotein bindingprotein bindingprotein transporter activityprotein transporter activityhormone bindinghormone bindingamide bindingamide binding
cellorganellemembraneprotein-containing complexcellorganellemembraneprotein-containing complexcellorganellemembraneprotein-containing complexcellorganellemembraneprotein-containing complexcellorganellemembraneprotein-containing complexcellorganellemembraneprotein-containing complexcellorganellemembraneprotein-containing complexcellorganellemembraneprotein-containing complexcellorganellemembraneprotein-containing complexcellorganellemembraneprotein-containing complexcellcellorganelleorganellemembranemembraneprotein-containing complexprotein-containing complex
TypeGO IDTermEv.Code
 biological_processGO:0001525 angiogenesis IDA
 biological_processGO:0001570 vasculogenesis IMP
 biological_processGO:0001666 response to hypoxia IEA
 biological_processGO:0002040 sprouting angiogenesis ISS
 biological_processGO:0006816 calcium ion transport IDA
 biological_processGO:0006886 intracellular protein transport IEA
 biological_processGO:0007186 G-protein coupled receptor signaling pathway TAS
 biological_processGO:0007189 adenylate cyclase-activating G-protein coupled receptor signaling pathway IPI
 biological_processGO:0007507 heart development ISS
 biological_processGO:0007565 female pregnancy IEA
 biological_processGO:0008217 regulation of blood pressure ISS
 biological_processGO:0008277 regulation of G-protein coupled receptor protein signaling pathway IEA
 biological_processGO:0010628 positive regulation of gene expression IDA
 biological_processGO:0015031 protein transport IDA
 biological_processGO:0031623 receptor internalization IDA
 biological_processGO:0032355 response to estradiol IEA
 biological_processGO:0032570 response to progesterone IEA
 biological_processGO:0032870 cellular response to hormone stimulus IEA
 biological_processGO:0034333 adherens junction assembly IDA
 biological_processGO:0035924 cellular response to vascular endothelial growth factor stimulus ISS
 biological_processGO:0043116 negative regulation of vascular permeability IDA
 biological_processGO:0045766 positive regulation of angiogenesis ISS
 biological_processGO:0070830 bicellular tight junction assembly IDA
 biological_processGO:0070831 basement membrane assembly ISS
 biological_processGO:0072659 protein localization to plasma membrane IDA
 biological_processGO:0097084 vascular smooth muscle cell development ISS
 biological_processGO:0097647 amylin receptor signaling pathway IGI
 biological_processGO:1990410 adrenomedullin receptor signaling pathway IPI
 biological_processGO:2000352 negative regulation of endothelial cell apoptotic process IDA
 biological_processGO:2001214 positive regulation of vasculogenesis IEA
 cellular_componentGO:0005737 cytoplasm IDA
 cellular_componentGO:0005764 lysosome TAS
 cellular_componentGO:0005886 plasma membrane TAS
 cellular_componentGO:0005887 integral component of plasma membrane TAS
 cellular_componentGO:0005905 clathrin-coated pit TAS
 cellular_componentGO:0009986 cell surface IDA
 cellular_componentGO:0043235 receptor complex IDA
 cellular_componentGO:1903143 adrenomedullin receptor complex IDA
 cellular_componentGO:1903440 amylin receptor complex IDA
 molecular_functionGO:0001605 adrenomedullin receptor activity IPI
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0008565 protein transporter activity IDA
 molecular_functionGO:0015026 coreceptor activity ISS
 molecular_functionGO:0097643 amylin receptor activity IGI
 molecular_functionGO:1990409 adrenomedullin binding IPI


Pathways (from Reactome)
Pathway description
No match


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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