1027


Homo sapiens (NCBI)

Features
Gene ID: 1027
  
Biological name :
  
Synonyms : CDKN1B / CDKN4|KIP1|MEN1B|MEN4|P27KIP1 / cyclin dependent kinase inhibitor 1B
  
Possible biological names infered from orthology :
  
Species: Homo sapiens (NCBI)
  
Chr. number:
Strand:
Band:
Gene start:
Gene end:
  
Corresponding Affymetrix probe sets: 209112_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: RefSeq - 4757962
RefSeq - NC_000012.12
RefSeq - NG_016341.1
RefSeq - NP_004055.1
RefSeq - NM_004064.4
  
See co-cited genes in PubMed
Warning: Please see the Ensembl gene model ENSG00000111276 to get all the annotations available for this gene.


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0000079 regulation of cyclin-dependent protein serine/threonine kinase activity TAS
 biological_processGO:0000082 G1/S transition of mitotic cell cycle TAS
 biological_processGO:0001666 response to hypoxia IEA
 biological_processGO:0001890 placenta development IEA
 biological_processGO:0006813 potassium ion transport IEA
 biological_processGO:0006977 DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest TAS
 biological_processGO:0007050 cell cycle arrest IMP
 biological_processGO:0007096 regulation of exit from mitosis IEA
 biological_processGO:0007219 Notch signaling pathway IEA
 biological_processGO:0007605 sensory perception of sound IEA
 biological_processGO:0008284 positive regulation of cell proliferation IEA
 biological_processGO:0008285 negative regulation of cell proliferation IMP
 biological_processGO:0009749 response to glucose IEA
 biological_processGO:0010942 positive regulation of cell death IDA
 biological_processGO:0030308 negative regulation of cell growth IDA
 biological_processGO:0031116 positive regulation of microtubule polymerization IEA
 biological_processGO:0032355 response to estradiol IEA
 biological_processGO:0033673 negative regulation of kinase activity IDA
 biological_processGO:0042326 negative regulation of phosphorylation IDA
 biological_processGO:0042493 response to drug IEA
 biological_processGO:0043066 negative regulation of apoptotic process IEA
 biological_processGO:0043200 response to amino acid IEA
 biological_processGO:0043434 response to peptide hormone IEA
 biological_processGO:0045732 positive regulation of protein catabolic process IDA
 biological_processGO:0045736 negative regulation of cyclin-dependent protein serine/threonine kinase activity IDA
 biological_processGO:0045737 positive regulation of cyclin-dependent protein serine/threonine kinase activity IEA
 biological_processGO:0045786 negative regulation of cell cycle IMP
 biological_processGO:0045787 positive regulation of cell cycle TAS
 biological_processGO:0045892 negative regulation of transcription, DNA-templated IDA
 biological_processGO:0045930 negative regulation of mitotic cell cycle IDA
 biological_processGO:0046686 response to cadmium ion IEA
 biological_processGO:0048102 autophagic cell death IDA
 biological_processGO:0048839 inner ear development IEA
 biological_processGO:0051271 negative regulation of cellular component movement IEA
 biological_processGO:0060770 negative regulation of epithelial cell proliferation involved in prostate gland development IEA
 biological_processGO:0071236 cellular response to antibiotic IEA
 biological_processGO:0071285 cellular response to lithium ion IDA
 biological_processGO:0071407 cellular response to organic cyclic compound IEA
 biological_processGO:0071850 mitotic cell cycle arrest IDA
 biological_processGO:1902746 regulation of lens fiber cell differentiation IEA
 biological_processGO:1904030 negative regulation of cyclin-dependent protein kinase activity IMP
 biological_processGO:1904706 negative regulation of vascular smooth muscle cell proliferation IMP
 cellular_componentGO:0005634 nucleus IDA
 cellular_componentGO:0005654 nucleoplasm TAS
 cellular_componentGO:0005737 cytoplasm IDA
 cellular_componentGO:0005768 endosome IEA
 cellular_componentGO:0005829 cytosol TAS
 cellular_componentGO:0031464 Cul4A-RING E3 ubiquitin ligase complex IDA
 cellular_componentGO:0043231 intracellular membrane-bounded organelle IDA
 molecular_functionGO:0004693 cyclin-dependent protein serine/threonine kinase activity EXP
 molecular_functionGO:0004860 protein kinase inhibitor activity IMP
 molecular_functionGO:0004861 cyclin-dependent protein serine/threonine kinase inhibitor activity TAS
 molecular_functionGO:0005072 transforming growth factor beta receptor, cytoplasmic mediator activity TAS
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0019901 protein kinase binding IPI
 molecular_functionGO:0019903 protein phosphatase binding IPI
 molecular_functionGO:0030332 cyclin binding IPI
 molecular_functionGO:0030544 Hsp70 protein binding IEA
 molecular_functionGO:0044877 protein-containing complex binding IPI
 molecular_functionGO:0051087 chaperone binding IEA


Pathways (from Reactome)
Pathway description
No match


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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