10333


Homo sapiens (NCBI)

Features
Gene ID: 10333
  
Biological name :
  
Synonyms : CD286 / TLR6 / toll like receptor 6
  
Possible biological names infered from orthology :
  
Species: Homo sapiens (NCBI)
  
Chr. number:
Strand:
Band:
Gene start:
Gene end:
  
Corresponding Affymetrix probe sets: 207446_at (Human Genome U133 Plus 2.0 Array)   239021_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: RefSeq - XP_024309641.1
RefSeq - 20143971
RefSeq - 530376455
RefSeq - 767930163
RefSeq - 767930165
RefSeq - NC_000004.12
RefSeq - NG_028087.1
RefSeq - NP_006059.2
RefSeq - XP_005262694.1
RefSeq - XP_011511915.1
RefSeq - XP_011511916.1
RefSeq - 1370486055
RefSeq - NM_006068.4
RefSeq - XM_024453873.1
RefSeq - XM_005262637.5
RefSeq - XM_011513613.3
RefSeq - XM_011513614.3
  
See co-cited genes in PubMed
Warning: Please see the Ensembl gene model ENSG00000174130 to get all the annotations available for this gene.


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0001774 microglial cell activation IEA
 biological_processGO:0001775 cell activation IDA
 biological_processGO:0002224 toll-like receptor signaling pathway TAS
 biological_processGO:0002755 MyD88-dependent toll-like receptor signaling pathway TAS
 biological_processGO:0006954 inflammatory response IEA
 biological_processGO:0006955 immune response TAS
 biological_processGO:0007165 signal transduction TAS
 biological_processGO:0007250 activation of NF-kappaB-inducing kinase activity NAS
 biological_processGO:0010628 positive regulation of gene expression ISS
 biological_processGO:0034136 negative regulation of toll-like receptor 2 signaling pathway IGI
 biological_processGO:0034150 toll-like receptor 6 signaling pathway IEA
 biological_processGO:0035666 TRIF-dependent toll-like receptor signaling pathway ISS
 biological_processGO:0038124 toll-like receptor TLR6:TLR2 signaling pathway TAS
 biological_processGO:0042496 detection of diacyl bacterial lipopeptide IDA
 biological_processGO:0042742 defense response to bacterium TAS
 biological_processGO:0043032 positive regulation of macrophage activation ISS
 biological_processGO:0043123 positive regulation of I-kappaB kinase/NF-kappaB signaling IDA
 biological_processGO:0043507 positive regulation of JUN kinase activity IDA
 biological_processGO:0045087 innate immune response IEA
 biological_processGO:0045410 positive regulation of interleukin-6 biosynthetic process ISS
 biological_processGO:0045429 positive regulation of nitric oxide biosynthetic process ISS
 biological_processGO:0046209 nitric oxide metabolic process IEA
 biological_processGO:0050702 interleukin-1 beta secretion ISS
 biological_processGO:0051092 positive regulation of NF-kappaB transcription factor activity IGI
 biological_processGO:0071221 cellular response to bacterial lipopeptide IBA
 biological_processGO:0071726 cellular response to diacyl bacterial lipopeptide IDA
 biological_processGO:0140052 cellular response to oxidised low-density lipoprotein particle stimulus ISS
 biological_processGO:1900017 positive regulation of cytokine production involved in inflammatory response ISS
 biological_processGO:1900227 positive regulation of NLRP3 inflammasome complex assembly ISS
 biological_processGO:1903223 positive regulation of oxidative stress-induced neuron death ISS
 biological_processGO:1903428 positive regulation of reactive oxygen species biosynthetic process ISS
 biological_processGO:1904646 cellular response to amyloid-beta IGI
 biological_processGO:2000483 negative regulation of interleukin-8 secretion IGI
 cellular_componentGO:0005622 intracellular IPI
 cellular_componentGO:0005794 Golgi apparatus IDA
 cellular_componentGO:0005886 plasma membrane TAS
 cellular_componentGO:0005887 integral component of plasma membrane TAS
 cellular_componentGO:0030670 phagocytic vesicle membrane IEA
 cellular_componentGO:0035355 Toll-like receptor 2-Toll-like receptor 6 protein complex IBA
 cellular_componentGO:0043235 receptor complex IPI
 cellular_componentGO:0045121 membrane raft IDA
 molecular_functionGO:0005102 signaling receptor binding IPI
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0035663 Toll-like receptor 2 binding IPI
 molecular_functionGO:0038023 signaling receptor activity TAS
 molecular_functionGO:0042802 identical protein binding IPI
 molecular_functionGO:0046982 protein heterodimerization activity IPI
 molecular_functionGO:0071723 lipopeptide binding ISS


Pathways (from Reactome)
Pathway description
No match


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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