10461


Homo sapiens (NCBI)

Features
Gene ID: 10461
  
Biological name :
  
Synonyms : MER proto-oncogene, tyrosine kinase / MER|RP38|Tyro12|c-Eyk|c-mer / MERTK
  
Possible biological names infered from orthology :
  
Species: Homo sapiens (NCBI)
  
Chr. number:
Strand:
Band:
Gene start:
Gene end:
  
Corresponding Affymetrix probe sets: 206028_s_at (Human Genome U133 Plus 2.0 Array)   211912_at (Human Genome U133 Plus 2.0 Array)   211913_s_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: RefSeq - 1034611047
RefSeq - 1034611051
RefSeq - 530368986
RefSeq - 530368992
RefSeq - 66932918
RefSeq - 767916352
RefSeq - NC_000002.12
RefSeq - NG_011607.1
RefSeq - NP_006334.2
RefSeq - XP_005263622.1
RefSeq - XP_005263625.1
RefSeq - XP_011508792.1
RefSeq - XP_016858653.1
RefSeq - XP_016858654.1
RefSeq - NM_006343.2
RefSeq - XM_017003165.2
RefSeq - XM_005263565.4
RefSeq - XM_005263568.4
RefSeq - XM_011510490.3
RefSeq - XM_017003164.1
  
See co-cited genes in PubMed
Warning: Please see the Ensembl gene model ENSG00000153208 to get all the annotations available for this gene.


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0001779 natural killer cell differentiation IEA
 biological_processGO:0001818 negative regulation of cytokine production IEA
 biological_processGO:0006468 protein phosphorylation TAS
 biological_processGO:0006909 phagocytosis IMP
 biological_processGO:0007166 cell surface receptor signaling pathway TAS
 biological_processGO:0007267 cell-cell signaling TAS
 biological_processGO:0007275 multicellular organism development IBA
 biological_processGO:0007283 spermatogenesis IEA
 biological_processGO:0009968 negative regulation of signal transduction IBA
 biological_processGO:0016055 Wnt signaling pathway IBA
 biological_processGO:0018108 peptidyl-tyrosine phosphorylation IEA
 biological_processGO:0030154 cell differentiation IBA
 biological_processGO:0030168 platelet activation IEA
 biological_processGO:0032940 secretion by cell IEA
 biological_processGO:0033674 positive regulation of kinase activity IBA
 biological_processGO:0034446 substrate adhesion-dependent cell spreading IEA
 biological_processGO:0043066 negative regulation of apoptotic process IBA
 biological_processGO:0043277 apoptotic cell clearance IEA
 biological_processGO:0043410 positive regulation of MAPK cascade IBA
 biological_processGO:0043491 protein kinase B signaling IEA
 biological_processGO:0050766 positive regulation of phagocytosis IDA
 biological_processGO:0050900 leukocyte migration TAS
 biological_processGO:0051250 negative regulation of lymphocyte activation IEA
 biological_processGO:0060041 retina development in camera-type eye IEA
 biological_processGO:0060068 vagina development IEA
 biological_processGO:0070374 positive regulation of ERK1 and ERK2 cascade IBA
 biological_processGO:0097350 neutrophil clearance IEA
 biological_processGO:2000107 negative regulation of leukocyte apoptotic process IMP
 cellular_componentGO:0001750 photoreceptor outer segment IEA
 cellular_componentGO:0005615 extracellular space IDA
 cellular_componentGO:0005737 cytoplasm IDA
 cellular_componentGO:0005886 plasma membrane TAS
 cellular_componentGO:0005887 integral component of plasma membrane TAS
 cellular_componentGO:0016028 rhabdomere IDA
 cellular_componentGO:0043235 receptor complex IBA
 molecular_functionGO:0004709 MAP kinase kinase kinase activity IBA
 molecular_functionGO:0004713 protein tyrosine kinase activity IBA
 molecular_functionGO:0004714 transmembrane receptor protein tyrosine kinase activity IEA
 molecular_functionGO:0004888 transmembrane signaling receptor activity IBA
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0005524 ATP binding IEA
 molecular_functionGO:0017147 Wnt-protein binding IBA
 molecular_functionGO:0031434 mitogen-activated protein kinase kinase binding IBA


Pathways (from Reactome)
Pathway description
No match


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

0 s.

 
External programs and data are copyrighted by and are the property of their respective authors.
The Manteia system, data and analyses are provided "as is" with no warranties, expressed or implied as to capabilities or accuracy. User assumes the entire risk as to the results and performance of the software, data and documentation


                   

© Olivier Tassy / Olivier Pourquie 2007-2025
contact: otassy@igbmc.fr