1080


Homo sapiens (NCBI)

Features
Gene ID: 1080
  
Biological name :
  
Synonyms : ABC35|ABCC7|CF|CFTR/MRP|MRP7|TNR-CFTR|dJ760C5.1 / CFTR / cystic fibrosis transmembrane conductance regulator
  
Possible biological names infered from orthology :
  
Species: Homo sapiens (NCBI)
  
Chr. number:
Strand:
Band:
Gene start:
Gene end:
  
Corresponding Affymetrix probe sets: 205043_at (Human Genome U133 Plus 2.0 Array)   215702_s_at (Human Genome U133 Plus 2.0 Array)   215703_at (Human Genome U133 Plus 2.0 Array)   217026_at (Human Genome U133 Plus 2.0 Array)   234702_x_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: RefSeq - 90421313
RefSeq - NC_000007.14
RefSeq - NG_016465.4
RefSeq - NP_000483.3
RefSeq - NM_000492.3
  
See co-cited genes in PubMed
Warning: Please see the Ensembl gene model ENSG00000001626 to get all the annotations available for this gene.


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006695 cholesterol biosynthetic process IEA
 biological_processGO:0006904 vesicle docking involved in exocytosis IEA
 biological_processGO:0015701 bicarbonate transport IDA
 biological_processGO:0016579 protein deubiquitination TAS
 biological_processGO:0030301 cholesterol transport IEA
 biological_processGO:0035377 transepithelial water transport IMP
 biological_processGO:0035774 positive regulation of insulin secretion involved in cellular response to glucose stimulus IMP
 biological_processGO:0045921 positive regulation of exocytosis IMP
 biological_processGO:0048240 sperm capacitation ISS
 biological_processGO:0050891 multicellular organismal water homeostasis IMP
 biological_processGO:0051454 intracellular pH elevation ISS
 biological_processGO:0055085 transmembrane transport TAS
 biological_processGO:0060081 membrane hyperpolarization ISS
 biological_processGO:0061024 membrane organization TAS
 biological_processGO:0071320 cellular response to cAMP ISS
 biological_processGO:0099133 ATP hydrolysis coupled anion transmembrane transport IEA
 biological_processGO:1902161 positive regulation of cyclic nucleotide-gated ion channel activity IMP
 biological_processGO:1902476 chloride transmembrane transport IMP
 biological_processGO:1902943 positive regulation of voltage-gated chloride channel activity IDA
 biological_processGO:1904322 cellular response to forskolin IDA
 cellular_componentGO:0005634 nucleus ISS
 cellular_componentGO:0005737 cytoplasm IDA
 cellular_componentGO:0005765 lysosomal membrane TAS
 cellular_componentGO:0005769 early endosome IDA
 cellular_componentGO:0005789 endoplasmic reticulum membrane TAS
 cellular_componentGO:0005829 cytosol TAS
 cellular_componentGO:0005886 plasma membrane TAS
 cellular_componentGO:0005887 integral component of plasma membrane IMP
 cellular_componentGO:0009986 cell surface IDA
 cellular_componentGO:0010008 endosome membrane TAS
 cellular_componentGO:0016020 membrane IBA
 cellular_componentGO:0016021 integral component of membrane IDA
 cellular_componentGO:0016324 apical plasma membrane IMP
 cellular_componentGO:0030660 Golgi-associated vesicle membrane TAS
 cellular_componentGO:0030665 clathrin-coated vesicle membrane TAS
 cellular_componentGO:0031205 endoplasmic reticulum Sec complex IDA
 cellular_componentGO:0031901 early endosome membrane IEA
 cellular_componentGO:0032991 protein-containing complex IDA
 cellular_componentGO:0034707 chloride channel complex IEA
 cellular_componentGO:0055037 recycling endosome IDA
 cellular_componentGO:0055038 recycling endosome membrane IEA
 molecular_functionGO:0005254 chloride channel activity IMP
 molecular_functionGO:0005260 intracellularly ATP-gated chloride channel activity NAS
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0005524 ATP binding IEA
 molecular_functionGO:0015106 bicarbonate transmembrane transporter activity ISS
 molecular_functionGO:0015108 chloride transmembrane transporter activity TAS
 molecular_functionGO:0016887 ATPase activity IDA
 molecular_functionGO:0017081 chloride channel regulator activity TAS
 molecular_functionGO:0019869 chloride channel inhibitor activity IDA
 molecular_functionGO:0019899 enzyme binding IPI
 molecular_functionGO:0030165 PDZ domain binding IDA
 molecular_functionGO:0042626 ATPase activity, coupled to transmembrane movement of substances IBA
 molecular_functionGO:0043225 ATPase-coupled anion transmembrane transporter activity TAS
 molecular_functionGO:0051087 chaperone binding IPI


Pathways (from Reactome)
Pathway description
No match


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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