1111


Homo sapiens (NCBI)

Features
Gene ID: 1111
  
Biological name :
  
Synonyms : checkpoint kinase 1 / CHEK1 / CHK1
  
Possible biological names infered from orthology :
  
Species: Homo sapiens (NCBI)
  
Chr. number:
Strand:
Band:
Gene start:
Gene end:
  
Corresponding Affymetrix probe sets: 205393_s_at (Human Genome U133 Plus 2.0 Array)   205394_at (Human Genome U133 Plus 2.0 Array)   229423_at (Human Genome U133 Plus 2.0 Array)   238075_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: RefSeq - 1034571802
RefSeq - 1060099147
RefSeq - 1060099302
RefSeq - 1370458671
RefSeq - 166295192
RefSeq - 166295194
RefSeq - 166295196
RefSeq - 349501061
RefSeq - 767969499
RefSeq - NC_000011.10
RefSeq - NG_030049.1
RefSeq - NP_001107593.1
RefSeq - NP_001107594.1
RefSeq - NP_001231775.1
RefSeq - NP_001265.2
RefSeq - NP_001317356.1
RefSeq - NP_001317357.1
RefSeq - XP_011540862.1
RefSeq - XP_016872635.1
RefSeq - XP_024304105.1
RefSeq - XM_011542560.2
RefSeq - XM_017017146.2
RefSeq - NM_001114121.2
RefSeq - NM_001114122.2
RefSeq - NM_001244846.1
RefSeq - NM_001274.5
RefSeq - NM_001330427.1
RefSeq - NM_001330428.1
RefSeq - XM_024448337.1
RefSeq - NR_045204.1
RefSeq - NR_045205.1
  
See co-cited genes in PubMed
Warning: Please see the Ensembl gene model ENSG00000149554 to get all the annotations available for this gene.


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0000077 DNA damage checkpoint IMP
 biological_processGO:0006260 DNA replication TAS
 biological_processGO:0006281 DNA repair IMP
 biological_processGO:0006468 protein phosphorylation IBA
 biological_processGO:0006915 apoptotic process IDA
 biological_processGO:0006974 cellular response to DNA damage stimulus IMP
 biological_processGO:0006975 DNA damage induced protein phosphorylation IDA
 biological_processGO:0007049 cell cycle IEA
 biological_processGO:0010569 regulation of double-strand break repair via homologous recombination IDA
 biological_processGO:0010767 regulation of transcription from RNA polymerase II promoter in response to UV-induced DNA damage ISS
 biological_processGO:0018107 peptidyl-threonine phosphorylation IDA
 biological_processGO:0035407 histone H3-T11 phosphorylation IEA
 biological_processGO:0035556 intracellular signal transduction IBA
 biological_processGO:0045787 positive regulation of cell cycle IDA
 biological_processGO:0045839 negative regulation of mitotic nuclear division IDA
 biological_processGO:0046602 regulation of mitotic centrosome separation IDA
 biological_processGO:0048096 chromatin-mediated maintenance of transcription ISS
 biological_processGO:0070317 negative regulation of G0 to G1 transition TAS
 biological_processGO:0071260 cellular response to mechanical stimulus IEP
 biological_processGO:0072425 signal transduction involved in G2 DNA damage checkpoint IMP
 biological_processGO:0090399 replicative senescence NAS
 biological_processGO:1901796 regulation of signal transduction by p53 class mediator TAS
 biological_processGO:2000615 regulation of histone H3-K9 acetylation ISS
 cellular_componentGO:0000781 chromosome, telomeric region IDA
 cellular_componentGO:0000785 chromatin ISS
 cellular_componentGO:0000794 condensed nuclear chromosome IDA
 cellular_componentGO:0005615 extracellular space HDA
 cellular_componentGO:0005634 nucleus IDA
 cellular_componentGO:0005654 nucleoplasm TAS
 cellular_componentGO:0005737 cytoplasm IDA
 cellular_componentGO:0005813 centrosome IDA
 cellular_componentGO:0005829 cytosol TAS
 cellular_componentGO:0032991 protein-containing complex IDA
 cellular_componentGO:0043231 intracellular membrane-bounded organelle IDA
 molecular_functionGO:0004672 protein kinase activity IMP
 molecular_functionGO:0004674 protein serine/threonine kinase activity TAS
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0005524 ATP binding IEA
 molecular_functionGO:0016301 kinase activity TAS
 molecular_functionGO:0019904 protein domain specific binding IPI
 molecular_functionGO:0035402 histone kinase activity (H3-T11 specific) IDA


Pathways (from Reactome)
Pathway description
No match


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

0 s.

 
External programs and data are copyrighted by and are the property of their respective authors.
The Manteia system, data and analyses are provided "as is" with no warranties, expressed or implied as to capabilities or accuracy. User assumes the entire risk as to the results and performance of the software, data and documentation


                   

© Olivier Tassy / Olivier Pourquie 2007-2024
contact: otassy@igbmc.fr