114548


Homo sapiens (NCBI)

Features
Gene ID: 114548
  
Biological name :
  
Synonyms : AGTAVPRL|AII|AVP|C1orf7|CIAS1|CLR1.1|DFNA34|FCAS|FCAS1|FCU|KEFH|MWS|NALP3|PYPAF1 / NLR family pyrin domain containing 3 / NLRP3
  
Possible biological names infered from orthology :
  
Species: Homo sapiens (NCBI)
  
Chr. number:
Strand:
Band:
Gene start:
Gene end:
  
Corresponding Affymetrix probe sets: 207075_at (Human Genome U133 Plus 2.0 Array)   216015_s_at (Human Genome U133 Plus 2.0 Array)   216016_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: RefSeq - 34878690
RefSeq - 1034555108
RefSeq - 1034555110
RefSeq - 1034555113
RefSeq - 119395764
RefSeq - 1370451776
RefSeq - 1370451778
RefSeq - 188536002
RefSeq - 188536116
RefSeq - 341865590
RefSeq - 1034555106
RefSeq - 34878693
RefSeq - 767912102
RefSeq - NC_000001.11
RefSeq - NG_007509.2
RefSeq - NP_001073289.1
RefSeq - NP_001120933.1
RefSeq - NP_001120934.1
RefSeq - NP_001230062.1
RefSeq - NP_004886.3
RefSeq - NP_899632.1
RefSeq - XP_011542350.1
RefSeq - XP_016855670.1
RefSeq - XP_016855671.1
RefSeq - XP_016855672.1
RefSeq - XP_016855673.1
RefSeq - XP_024308630.1
RefSeq - XP_024308642.1
RefSeq - NM_001079821.2
RefSeq - NM_001127461.2
RefSeq - NM_001127462.2
RefSeq - NM_001243133.1
RefSeq - NM_004895.4
RefSeq - NM_183395.2
RefSeq - XM_017000181.1
RefSeq - XM_017000182.1
RefSeq - XM_017000183.1
RefSeq - XM_017000184.1
RefSeq - XM_024452862.1
RefSeq - XM_024452874.1
RefSeq - XM_011544048.2
  
See co-cited genes in PubMed
Warning: Please see the Ensembl gene model ENSG00000162711 to get all the annotations available for this gene.


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0002374 cytokine secretion involved in immune response IEA
 biological_processGO:0002674 negative regulation of acute inflammatory response IMP
 biological_processGO:0002830 positive regulation of type 2 immune response ISS
 biological_processGO:0006351 transcription, DNA-templated IEA
 biological_processGO:0006915 apoptotic process NAS
 biological_processGO:0006919 activation of cysteine-type endopeptidase activity involved in apoptotic process IEA
 biological_processGO:0006952 defense response TAS
 biological_processGO:0006954 inflammatory response IMP
 biological_processGO:0007165 signal transduction NAS
 biological_processGO:0009595 detection of biotic stimulus TAS
 biological_processGO:0009617 response to bacterium IBA
 biological_processGO:0016579 protein deubiquitination TAS
 biological_processGO:0032088 negative regulation of NF-kappaB transcription factor activity IDA
 biological_processGO:0032611 interleukin-1 beta production IEA
 biological_processGO:0032621 interleukin-18 production IEA
 biological_processGO:0032736 positive regulation of interleukin-13 production IEA
 biological_processGO:0032753 positive regulation of interleukin-4 production ISS
 biological_processGO:0032754 positive regulation of interleukin-5 production IEA
 biological_processGO:0043280 positive regulation of cysteine-type endopeptidase activity involved in apoptotic process IDA
 biological_processGO:0044546 NLRP3 inflammasome complex assembly IEA
 biological_processGO:0045087 innate immune response IEA
 biological_processGO:0045630 positive regulation of T-helper 2 cell differentiation ISS
 biological_processGO:0045944 positive regulation of transcription by RNA polymerase II ISS
 biological_processGO:0050701 interleukin-1 secretion IEA
 biological_processGO:0050713 negative regulation of interleukin-1 beta secretion IMP
 biological_processGO:0050718 positive regulation of interleukin-1 beta secretion IDA
 biological_processGO:0050728 negative regulation of inflammatory response IMP
 biological_processGO:0050830 defense response to Gram-positive bacterium IEA
 biological_processGO:0051092 positive regulation of NF-kappaB transcription factor activity IPI
 biological_processGO:0051259 protein complex oligomerization TAS
 biological_processGO:0051607 defense response to virus IEA
 biological_processGO:0071222 cellular response to lipopolysaccharide IMP
 biological_processGO:0071224 cellular response to peptidoglycan IEA
 biological_processGO:1901223 negative regulation of NIK/NF-kappaB signaling IDA
 biological_processGO:2000321 positive regulation of T-helper 17 cell differentiation IEA
 biological_processGO:2000553 positive regulation of T-helper 2 cell cytokine production ISS
 cellular_componentGO:0005576 extracellular region IEA
 cellular_componentGO:0005634 nucleus ISS
 cellular_componentGO:0005737 cytoplasm TAS
 cellular_componentGO:0005783 endoplasmic reticulum IEA
 cellular_componentGO:0005829 cytosol TAS
 cellular_componentGO:0072559 NLRP3 inflammasome complex IDA
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0005524 ATP binding IEA
 molecular_functionGO:0008134 transcription factor binding ISS
 molecular_functionGO:0042802 identical protein binding IPI
 molecular_functionGO:0042834 peptidoglycan binding TAS
 molecular_functionGO:0043565 sequence-specific DNA binding ISS


Pathways (from Reactome)
Pathway description
No match


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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