114609


Homo sapiens (NCBI)

Features
Gene ID: 114609
  
Biological name :
  
Synonyms : BACTS1|Mal|MyD88-2|wyatt / TIRAP / TIR domain containing adaptor protein
  
Possible biological names infered from orthology :
  
Species: Homo sapiens (NCBI)
  
Chr. number:
Strand:
Band:
Gene start:
Gene end:
  
Corresponding Affymetrix probe sets: 1552360_a_at (Human Genome U133 Plus 2.0 Array)   1552804_a_at (Human Genome U133 Plus 2.0 Array)   1554091_a_at (Human Genome U133 Plus 2.0 Array)   239796_x_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: RefSeq - 22547219
RefSeq - 89111122
RefSeq - 974005191
RefSeq - 974005197
RefSeq - NC_000011.10
RefSeq - NG_011523.1
RefSeq - NP_001034750.1
RefSeq - NP_001305705.1
RefSeq - NP_001305706.1
RefSeq - NP_683708.1
RefSeq - NM_148910.2
RefSeq - NM_001039661.1
RefSeq - NM_001318776.1
RefSeq - NM_001318777.1
RefSeq - NM_052887.2
  
See co-cited genes in PubMed
Warning: Please see the Ensembl gene model ENSG00000150455 to get all the annotations available for this gene.


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0002755 MyD88-dependent toll-like receptor signaling pathway TAS
 biological_processGO:0006954 inflammatory response IEA
 biological_processGO:0007166 cell surface receptor signaling pathway ISS
 biological_processGO:0007250 activation of NF-kappaB-inducing kinase activity IMP
 biological_processGO:0030099 myeloid cell differentiation ISS
 biological_processGO:0030890 positive regulation of B cell proliferation ISS
 biological_processGO:0032496 response to lipopolysaccharide IDA
 biological_processGO:0032648 regulation of interferon-beta production ISS
 biological_processGO:0032735 positive regulation of interleukin-12 production ISS
 biological_processGO:0032738 positive regulation of interleukin-15 production IDA
 biological_processGO:0032757 positive regulation of interleukin-8 production IMP
 biological_processGO:0032760 positive regulation of tumor necrosis factor production IMP
 biological_processGO:0034137 positive regulation of toll-like receptor 2 signaling pathway IMP
 biological_processGO:0034141 positive regulation of toll-like receptor 3 signaling pathway ISS
 biological_processGO:0034145 positive regulation of toll-like receptor 4 signaling pathway IMP
 biological_processGO:0035665 TIRAP-dependent toll-like receptor 4 signaling pathway IDA
 biological_processGO:0043123 positive regulation of I-kappaB kinase/NF-kappaB signaling IMP
 biological_processGO:0044130 negative regulation of growth of symbiont in host ISS
 biological_processGO:0045087 innate immune response IEA
 biological_processGO:0045088 regulation of innate immune response IC
 biological_processGO:0045410 positive regulation of interleukin-6 biosynthetic process IMP
 biological_processGO:0046330 positive regulation of JNK cascade IMP
 biological_processGO:0050830 defense response to Gram-positive bacterium ISS
 biological_processGO:0051092 positive regulation of NF-kappaB transcription factor activity IMP
 biological_processGO:0070374 positive regulation of ERK1 and ERK2 cascade IMP
 biological_processGO:0070935 3"-UTR-mediated mRNA stabilization IDA
 biological_processGO:0071221 cellular response to bacterial lipopeptide ISS
 biological_processGO:0071223 cellular response to lipoteichoic acid ISS
 biological_processGO:0090023 positive regulation of neutrophil chemotaxis ISS
 biological_processGO:0090073 positive regulation of protein homodimerization activity IDA
 biological_processGO:2000340 positive regulation of chemokine (C-X-C motif) ligand 1 production ISS
 biological_processGO:2000343 positive regulation of chemokine (C-X-C motif) ligand 2 production ISS
 cellular_componentGO:0005737 cytoplasm IDA
 cellular_componentGO:0005829 cytosol TAS
 cellular_componentGO:0005886 plasma membrane TAS
 cellular_componentGO:0030139 endocytic vesicle ISS
 cellular_componentGO:0032587 ruffle membrane ISS
 molecular_functionGO:0005080 protein kinase C binding IPI
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0005546 phosphatidylinositol-4,5-bisphosphate binding ISS
 molecular_functionGO:0030674 protein binding, bridging NAS
 molecular_functionGO:0035662 Toll-like receptor 4 binding IPI
 molecular_functionGO:0035663 Toll-like receptor 2 binding IPI
 molecular_functionGO:0042802 identical protein binding IPI
 molecular_functionGO:0042803 protein homodimerization activity ISS
 molecular_functionGO:0046982 protein heterodimerization activity IDA


Pathways (from Reactome)
Pathway description
No match


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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