11477


Mus musculus (NCBI)

Features
Gene ID: 11477
  
Biological name :
  
Synonyms : activin A receptor, type 1 / Acvr1 / ALK2|ActR-I|ActRIA|Acvr|Acvr1a|Acvrlk2|Alk-2|Alk8|D330013D15Rik|SKR1|Tsk7L
  
Possible biological names infered from orthology :
  
Species: Mus musculus (NCBI)
  
Chr. number:
Strand:
Band:
Gene start:
Gene end:
  
Corresponding Affymetrix probe sets: 1416786_at (Mouse Genome 430 2.0 Array)   1416787_at (Mouse Genome 430 2.0 Array)   1448460_at (Mouse Genome 430 2.0 Array)   
  
Cross references: RefSeq - 1039758822
RefSeq - 1039758825
RefSeq - 1240085898
RefSeq - 1240085922
RefSeq - 158937274
RefSeq - 158937276
RefSeq - 40254649
RefSeq - 568912814
RefSeq - NC_000068.7
RefSeq - NP_001103674.1
RefSeq - NP_001103675.1
RefSeq - NP_001341977.1
RefSeq - NP_001341978.1
RefSeq - NP_031420.2
RefSeq - XP_006497685.1
RefSeq - XP_017170494.1
RefSeq - XP_017170495.1
RefSeq - NM_001110204.1
RefSeq - NM_001110205.1
RefSeq - NM_001355048.1
RefSeq - NM_001355049.1
RefSeq - NM_007394.3
RefSeq - XM_017315005.1
RefSeq - XM_017315006.1
RefSeq - XM_006497622.3
  
See co-cited genes in PubMed
Warning: Please see the Ensembl gene model ENSMUSG00000026836 to get all the annotations available for this gene.


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0000082 G1/S transition of mitotic cell cycle ISO
 biological_processGO:0001569 branching involved in blood vessel morphogenesis IMP
 biological_processGO:0001655 urogenital system development ISO
 biological_processGO:0001701 in utero embryonic development IMP
 biological_processGO:0001702 gastrulation with mouth forming second IMP
 biological_processGO:0001707 mesoderm formation IMP
 biological_processGO:0001755 neural crest cell migration IMP
 biological_processGO:0002526 acute inflammatory response IEP
 biological_processGO:0003143 embryonic heart tube morphogenesis ISO
 biological_processGO:0003148 outflow tract septum morphogenesis IMP
 biological_processGO:0003181 atrioventricular valve morphogenesis IMP
 biological_processGO:0003183 mitral valve morphogenesis ISO
 biological_processGO:0003203 endocardial cushion morphogenesis IMP
 biological_processGO:0003274 endocardial cushion fusion IMP
 biological_processGO:0003289 atrial septum primum morphogenesis ISO
 biological_processGO:0006468 protein phosphorylation ISO
 biological_processGO:0007178 transmembrane receptor protein serine/threonine kinase signaling pathway IEA
 biological_processGO:0007179 transforming growth factor beta receptor signaling pathway TAS
 biological_processGO:0007281 germ cell development IMP
 biological_processGO:0007368 determination of left/right symmetry IMP
 biological_processGO:0007369 gastrulation IMP
 biological_processGO:0007389 pattern specification process IBA
 biological_processGO:0007498 mesoderm development IMP
 biological_processGO:0007507 heart development IMP
 biological_processGO:0009968 negative regulation of signal transduction ISO
 biological_processGO:0010862 positive regulation of pathway-restricted SMAD protein phosphorylation ISO
 biological_processGO:0016310 phosphorylation IEA
 biological_processGO:0018107 peptidyl-threonine phosphorylation ISO
 biological_processGO:0030278 regulation of ossification ISO
 biological_processGO:0030335 positive regulation of cell migration ISO
 biological_processGO:0030501 positive regulation of bone mineralization ISO
 biological_processGO:0030509 BMP signaling pathway ISO
 biological_processGO:0032924 activin receptor signaling pathway ISO
 biological_processGO:0032926 negative regulation of activin receptor signaling pathway ISO
 biological_processGO:0045669 positive regulation of osteoblast differentiation ISO
 biological_processGO:0045893 positive regulation of transcription, DNA-templated ISO
 biological_processGO:0045944 positive regulation of transcription by RNA polymerase II ISO
 biological_processGO:0051145 smooth muscle cell differentiation IMP
 biological_processGO:0060037 pharyngeal system development IMP
 biological_processGO:0060389 pathway-restricted SMAD protein phosphorylation ISO
 biological_processGO:0060412 ventricular septum morphogenesis IMP
 biological_processGO:0060923 cardiac muscle cell fate commitment ISO
 biological_processGO:0061312 BMP signaling pathway involved in heart development IMP
 biological_processGO:0061445 endocardial cushion cell fate commitment ISO
 biological_processGO:0071773 cellular response to BMP stimulus ISO
 biological_processGO:1905007 positive regulation of epithelial to mesenchymal transition involved in endocardial cushion formation IMP
 biological_processGO:2000017 positive regulation of determination of dorsal identity ISO
 biological_processGO:2001237 negative regulation of extrinsic apoptotic signaling pathway ISO
 cellular_componentGO:0005887 integral component of plasma membrane ISO
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 cellular_componentGO:0043235 receptor complex IBA
 cellular_componentGO:0045177 apical part of cell IDA
 cellular_componentGO:0048179 activin receptor complex ISO
 molecular_functionGO:0000166 nucleotide binding IEA
 molecular_functionGO:0004672 protein kinase activity ISO
 molecular_functionGO:0004674 protein serine/threonine kinase activity ISO
 molecular_functionGO:0004675 transmembrane receptor protein serine/threonine kinase activity IEA
 molecular_functionGO:0005024 transforming growth factor beta-activated receptor activity IBA
 molecular_functionGO:0005025 transforming growth factor beta receptor activity, type I IDA
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0005524 ATP binding ISO
 molecular_functionGO:0016301 kinase activity IEA
 molecular_functionGO:0016361 activin receptor activity, type I ISO
 molecular_functionGO:0016740 transferase activity IEA
 molecular_functionGO:0019838 growth factor binding IDA
 molecular_functionGO:0042803 protein homodimerization activity ISO
 molecular_functionGO:0046332 SMAD binding ISO
 molecular_functionGO:0046872 metal ion binding IEA
 molecular_functionGO:0048185 activin binding ISO
 molecular_functionGO:0050431 transforming growth factor beta binding ISO
 molecular_functionGO:0098821 BMP receptor activity IBA


Pathways (from Reactome)
Pathway description
No match


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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