11491


Mus musculus (NCBI)

Features
Gene ID: 11491
  
Biological name :
  
Synonyms : Adam17 / a disintegrin and metallopeptidase domain 17 / CD156b|Tace
  
Possible biological names infered from orthology :
  
Species: Mus musculus (NCBI)
  
Chr. number:
Strand:
Band:
Gene start:
Gene end:
  
Corresponding Affymetrix probe sets: 1421857_at (Mouse Genome 430 2.0 Array)   1421858_at (Mouse Genome 430 2.0 Array)   1421859_at (Mouse Genome 430 2.0 Array)   
  
Cross references: RefSeq - NP_001264195.1
RefSeq - NP_001278800.1
RefSeq - NP_033745.4
RefSeq - 471270257
RefSeq - 110347485
RefSeq - 630044862
RefSeq - NC_000078.6
RefSeq - NR_120376.1
RefSeq - NM_001277266.1
RefSeq - NM_001291871.1
RefSeq - NM_009615.6
RefSeq - NR_102380.1
  
See co-cited genes in PubMed
Warning: Please see the Ensembl gene model ENSMUSG00000052593 to get all the annotations available for this gene.


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0001666 response to hypoxia ISO
 biological_processGO:0001934 positive regulation of protein phosphorylation ISO
 biological_processGO:0002467 germinal center formation IMP
 biological_processGO:0002532 production of molecular mediator involved in inflammatory response IDA
 biological_processGO:0006508 proteolysis ISO
 biological_processGO:0006509 membrane protein ectodomain proteolysis ISO
 biological_processGO:0007155 cell adhesion ISO
 biological_processGO:0007173 epidermal growth factor receptor signaling pathway ISO
 biological_processGO:0007219 Notch signaling pathway IEA
 biological_processGO:0007220 Notch receptor processing ISO
 biological_processGO:0008284 positive regulation of cell proliferation ISO
 biological_processGO:0010820 positive regulation of T cell chemotaxis ISO
 biological_processGO:0010977 negative regulation of neuron projection development IGI
 biological_processGO:0030183 B cell differentiation IMP
 biological_processGO:0030307 positive regulation of cell growth ISO
 biological_processGO:0030335 positive regulation of cell migration ISO
 biological_processGO:0030511 positive regulation of transforming growth factor beta receptor signaling pathway IMP
 biological_processGO:0030512 negative regulation of transforming growth factor beta receptor signaling pathway ISO
 biological_processGO:0031659 positive regulation of cyclin-dependent protein serine/threonine kinase activity involved in G1/S transition of mitotic cell cycle ISO
 biological_processGO:0032496 response to lipopolysaccharide ISO
 biological_processGO:0032722 positive regulation of chemokine production ISO
 biological_processGO:0033025 regulation of mast cell apoptotic process IMP
 biological_processGO:0033077 T cell differentiation in thymus IMP
 biological_processGO:0033627 cell adhesion mediated by integrin ISO
 biological_processGO:0042493 response to drug IMP
 biological_processGO:0043066 negative regulation of apoptotic process ISO
 biological_processGO:0043536 positive regulation of blood vessel endothelial cell migration ISO
 biological_processGO:0045741 positive regulation of epidermal growth factor-activated receptor activity ISO
 biological_processGO:0048536 spleen development IMP
 biological_processGO:0048679 regulation of axon regeneration IGI
 biological_processGO:0048870 cell motility IMP
 biological_processGO:0050830 defense response to Gram-positive bacterium ISO
 biological_processGO:0051088 PMA-inducible membrane protein ectodomain proteolysis ISO
 biological_processGO:0051272 positive regulation of cellular component movement IMP
 biological_processGO:0071403 cellular response to high density lipoprotein particle stimulus ISO
 biological_processGO:1903265 positive regulation of tumor necrosis factor-mediated signaling pathway ISO
 biological_processGO:1905564 positive regulation of vascular endothelial cell proliferation ISO
 biological_processGO:2001222 regulation of neuron migration IGI
 cellular_componentGO:0005576 extracellular region IEA
 cellular_componentGO:0005615 extracellular space HDA
 cellular_componentGO:0005737 cytoplasm ISO
 cellular_componentGO:0005829 cytosol ISO
 cellular_componentGO:0005886 plasma membrane ISO
 cellular_componentGO:0005887 integral component of plasma membrane ISO
 cellular_componentGO:0005911 cell-cell junction ISO
 cellular_componentGO:0005925 focal adhesion ISO
 cellular_componentGO:0009986 cell surface ISO
 cellular_componentGO:0015629 actin cytoskeleton ISO
 cellular_componentGO:0016020 membrane IDA
 cellular_componentGO:0016021 integral component of membrane IEA
 cellular_componentGO:0016324 apical plasma membrane ISO
 cellular_componentGO:0032587 ruffle membrane ISO
 cellular_componentGO:0045121 membrane raft ISO
 molecular_functionGO:0004222 metalloendopeptidase activity ISO
 molecular_functionGO:0005112 Notch binding ISO
 molecular_functionGO:0005138 interleukin-6 receptor binding ISO
 molecular_functionGO:0005178 integrin binding ISO
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0008233 peptidase activity IEA
 molecular_functionGO:0008237 metallopeptidase activity ISO
 molecular_functionGO:0016787 hydrolase activity IEA
 molecular_functionGO:0017124 SH3 domain binding IEA
 molecular_functionGO:0030165 PDZ domain binding ISO
 molecular_functionGO:0046872 metal ion binding IEA


Pathways (from Reactome)
Pathway description
No match


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

0 s.

 
External programs and data are copyrighted by and are the property of their respective authors.
The Manteia system, data and analyses are provided "as is" with no warranties, expressed or implied as to capabilities or accuracy. User assumes the entire risk as to the results and performance of the software, data and documentation


                   

© Olivier Tassy / Olivier Pourquie 2007-2025
contact: otassy@igbmc.fr