11596


Mus musculus (NCBI)

Features
Gene ID: 11596
  
Biological name :
  
Synonyms : advanced glycosylation end product-specific receptor / Ager / RAGE
  
Possible biological names infered from orthology :
  
Species: Mus musculus (NCBI)
  
Chr. number:
Strand:
Band:
Gene start:
Gene end:
  
Corresponding Affymetrix probe sets: 1420428_at (Mouse Genome 430 2.0 Array)   1441958_s_at (Mouse Genome 430 2.0 Array)   
  
Cross references: RefSeq - XP_006523564.1
RefSeq - 406855404
RefSeq - 406855406
RefSeq - 406855408
RefSeq - 568998681
RefSeq - NC_000083.6
RefSeq - NP_001258351.1
RefSeq - NP_001258352.1
RefSeq - NP_001258353.1
RefSeq - NP_031451.2
RefSeq - NT_039662.3
RefSeq - NT_187004.1
RefSeq - NT_187027.1
RefSeq - 110225341
RefSeq - NM_001271422.1
RefSeq - NM_001271423.1
RefSeq - NM_001271424.1
RefSeq - NM_007425.3
RefSeq - NR_073173.1
RefSeq - NR_073175.1
RefSeq - NR_073176.1
RefSeq - XM_006523501.2
  
See co-cited genes in PubMed
Warning: Please see the Ensembl gene model ENSMUSG00000015452 to get all the annotations available for this gene.


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0001666 response to hypoxia IMP
 biological_processGO:0001914 regulation of T cell mediated cytotoxicity ISO
 biological_processGO:0001933 negative regulation of protein phosphorylation ISO
 biological_processGO:0001934 positive regulation of protein phosphorylation ISO
 biological_processGO:0001937 negative regulation of endothelial cell proliferation ISO
 biological_processGO:0006954 inflammatory response IGI
 biological_processGO:0007162 negative regulation of cell adhesion ISO
 biological_processGO:0007259 JAK-STAT cascade ISO
 biological_processGO:0007611 learning or memory ISO
 biological_processGO:0010255 glucose mediated signaling pathway ISO
 biological_processGO:0010508 positive regulation of autophagy ISO
 biological_processGO:0010596 negative regulation of endothelial cell migration ISO
 biological_processGO:0010628 positive regulation of gene expression ISO
 biological_processGO:0010718 positive regulation of epithelial to mesenchymal transition ISO
 biological_processGO:0010763 positive regulation of fibroblast migration ISO
 biological_processGO:0014002 astrocyte development IMP
 biological_processGO:0014911 positive regulation of smooth muscle cell migration ISO
 biological_processGO:0023056 positive regulation of signaling ISO
 biological_processGO:0023057 negative regulation of signaling ISO
 biological_processGO:0030335 positive regulation of cell migration ISO
 biological_processGO:0030336 negative regulation of cell migration ISO
 biological_processGO:0031175 neuron projection development ISO
 biological_processGO:0032693 negative regulation of interleukin-10 production ISO
 biological_processGO:0032735 positive regulation of interleukin-12 production ISO
 biological_processGO:0032966 negative regulation of collagen biosynthetic process ISO
 biological_processGO:0042104 positive regulation of activated T cell proliferation ISO
 biological_processGO:0043065 positive regulation of apoptotic process ISO
 biological_processGO:0043507 positive regulation of JUN kinase activity IMP
 biological_processGO:0043525 positive regulation of neuron apoptotic process ISO
 biological_processGO:0046330 positive regulation of JNK cascade ISO
 biological_processGO:0048146 positive regulation of fibroblast proliferation ISO
 biological_processGO:0048661 positive regulation of smooth muscle cell proliferation ISO
 biological_processGO:0050727 regulation of inflammatory response IDA
 biological_processGO:0050729 positive regulation of inflammatory response ISO
 biological_processGO:0050930 induction of positive chemotaxis IMP
 biological_processGO:0051092 positive regulation of NF-kappaB transcription factor activity ISO
 biological_processGO:0051101 regulation of DNA binding IMP
 biological_processGO:0055074 calcium ion homeostasis ISO
 biological_processGO:0060100 positive regulation of phagocytosis, engulfment ISO
 biological_processGO:0061890 positive regulation of astrocyte activation ISO
 biological_processGO:0070374 positive regulation of ERK1 and ERK2 cascade ISO
 biological_processGO:0071639 positive regulation of monocyte chemotactic protein-1 production IGI
 biological_processGO:0072657 protein localization to membrane IMP
 biological_processGO:0090647 modulation of age-related behavioral decline ISO
 biological_processGO:0150003 regulation of spontaneous synaptic transmission ISO
 biological_processGO:1900271 regulation of long-term synaptic potentiation IMP
 biological_processGO:1900272 negative regulation of long-term synaptic potentiation ISO
 biological_processGO:1900453 negative regulation of long term synaptic depression ISO
 biological_processGO:1900744 regulation of p38MAPK cascade IGI
 biological_processGO:1900745 positive regulation of p38MAPK cascade ISO
 biological_processGO:1901018 positive regulation of potassium ion transmembrane transporter activity ISO
 biological_processGO:1901216 positive regulation of neuron death ISO
 biological_processGO:1901224 positive regulation of NIK/NF-kappaB signaling ISO
 biological_processGO:1903980 positive regulation of microglial cell activation ISO
 biological_processGO:1904597 negative regulation of connective tissue replacement involved in inflammatory response wound healing IMP
 biological_processGO:1904604 negative regulation of advanced glycation end-product receptor activity ISO
 biological_processGO:1904605 positive regulation of advanced glycation end-product receptor activity ISO
 biological_processGO:1904645 response to amyloid-beta IGI
 biological_processGO:1904646 cellular response to amyloid-beta IMP
 biological_processGO:2000353 positive regulation of endothelial cell apoptotic process ISO
 biological_processGO:2000379 positive regulation of reactive oxygen species metabolic process ISO
 biological_processGO:2000514 regulation of CD4-positive, alpha-beta T cell activation ISO
 biological_processGO:2000676 positive regulation of type B pancreatic cell apoptotic process ISO
 biological_processGO:2001200 positive regulation of dendritic cell differentiation ISO
 cellular_componentGO:0001650 fibrillar center ISO
 cellular_componentGO:0005576 extracellular region ISO
 cellular_componentGO:0005615 extracellular space ISO
 cellular_componentGO:0005634 nucleus ISO
 cellular_componentGO:0005737 cytoplasm ISO
 cellular_componentGO:0005829 cytosol ISO
 cellular_componentGO:0005886 plasma membrane ISO
 cellular_componentGO:0009897 external side of plasma membrane ISO
 cellular_componentGO:0009925 basal plasma membrane ISO
 cellular_componentGO:0009986 cell surface ISO
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 cellular_componentGO:0016324 apical plasma membrane ISO
 cellular_componentGO:0030054 cell junction ISO
 cellular_componentGO:0030424 axon ISO
 cellular_componentGO:0043025 neuronal cell body ISO
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0008201 heparin binding IDA
 molecular_functionGO:0038023 signaling receptor activity ISO
 molecular_functionGO:0042802 identical protein binding ISO
 molecular_functionGO:0044548 S100 protein binding ISO
 molecular_functionGO:0050785 advanced glycation end-product receptor activity ISO
 molecular_functionGO:0070379 high mobility group box 1 binding ISO
 molecular_functionGO:1904599 advanced glycation end-product binding IDA


Pathways (from Reactome)
Pathway description
No match


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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