117149


Mus musculus (NCBI)

Features
Gene ID: 117149
  
Biological name :
  
Synonyms : AA407980|C130027E04Rik|Mal|Tlr4ap|Wyatt / Tirap / toll-interleukin 1 receptor (TIR) domain-containing adaptor protein
  
Possible biological names infered from orthology :
  
Species: Mus musculus (NCBI)
  
Chr. number:
Strand:
Band:
Gene start:
Gene end:
  
Corresponding Affymetrix probe sets: 1418685_at (Mouse Genome 430 2.0 Array)   1457676_at (Mouse Genome 430 2.0 Array)   
  
Cross references: RefSeq - 295390024
RefSeq - 295390033
RefSeq - 295390046
RefSeq - 295390061
RefSeq - NC_000075.6
RefSeq - NP_001171316.1
RefSeq - NP_001171317.1
RefSeq - NP_001171318.1
RefSeq - NP_473437.2
RefSeq - NM_001177845.1
RefSeq - NM_001177846.1
RefSeq - NM_001177847.1
RefSeq - NM_054096.2
  
See co-cited genes in PubMed
Warning: Please see the Ensembl gene model ENSMUSG00000032041 to get all the annotations available for this gene.


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0002376 immune system process IEA
 biological_processGO:0006954 inflammatory response IEA
 biological_processGO:0007165 signal transduction IEA
 biological_processGO:0007166 cell surface receptor signaling pathway ISO
 biological_processGO:0007249 I-kappaB kinase/NF-kappaB signaling ISO
 biological_processGO:0007250 activation of NF-kappaB-inducing kinase activity ISO
 biological_processGO:0007257 activation of JUN kinase activity ISO
 biological_processGO:0009617 response to bacterium ISO
 biological_processGO:0030099 myeloid cell differentiation IMP
 biological_processGO:0030890 positive regulation of B cell proliferation IMP
 biological_processGO:0032496 response to lipopolysaccharide ISO
 biological_processGO:0032648 regulation of interferon-beta production IDA
 biological_processGO:0032658 regulation of interleukin-15 production IMP
 biological_processGO:0032735 positive regulation of interleukin-12 production IMP
 biological_processGO:0032738 positive regulation of interleukin-15 production ISO
 biological_processGO:0032757 positive regulation of interleukin-8 production ISO
 biological_processGO:0032760 positive regulation of tumor necrosis factor production ISO
 biological_processGO:0034137 positive regulation of toll-like receptor 2 signaling pathway ISO
 biological_processGO:0034141 positive regulation of toll-like receptor 3 signaling pathway IDA
 biological_processGO:0034145 positive regulation of toll-like receptor 4 signaling pathway ISO
 biological_processGO:0034146 toll-like receptor 5 signaling pathway IMP
 biological_processGO:0035665 TIRAP-dependent toll-like receptor 4 signaling pathway ISO
 biological_processGO:0043123 positive regulation of I-kappaB kinase/NF-kappaB signaling ISO
 biological_processGO:0044130 negative regulation of growth of symbiont in host IMP
 biological_processGO:0045087 innate immune response IEA
 biological_processGO:0045088 regulation of innate immune response NAS
 biological_processGO:0045089 positive regulation of innate immune response IMP
 biological_processGO:0045410 positive regulation of interleukin-6 biosynthetic process ISO
 biological_processGO:0046330 positive regulation of JNK cascade ISO
 biological_processGO:0050830 defense response to Gram-positive bacterium IMP
 biological_processGO:0051092 positive regulation of NF-kappaB transcription factor activity ISO
 biological_processGO:0070374 positive regulation of ERK1 and ERK2 cascade ISO
 biological_processGO:0070498 interleukin-1-mediated signaling pathway NAS
 biological_processGO:0070935 3"-UTR-mediated mRNA stabilization ISO
 biological_processGO:0071221 cellular response to bacterial lipopeptide IMP
 biological_processGO:0071223 cellular response to lipoteichoic acid IMP
 biological_processGO:0090023 positive regulation of neutrophil chemotaxis IMP
 biological_processGO:0090073 positive regulation of protein homodimerization activity ISO
 biological_processGO:2000340 positive regulation of chemokine (C-X-C motif) ligand 1 production IMP
 biological_processGO:2000343 positive regulation of chemokine (C-X-C motif) ligand 2 production IMP
 cellular_componentGO:0005737 cytoplasm ISO
 cellular_componentGO:0005777 peroxisome IDA
 cellular_componentGO:0005886 plasma membrane ISO
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0030139 endocytic vesicle IDA
 cellular_componentGO:0032587 ruffle membrane IDA
 molecular_functionGO:0005080 protein kinase C binding ISO
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0005546 phosphatidylinositol-4,5-bisphosphate binding IDA
 molecular_functionGO:0035662 Toll-like receptor 4 binding ISO
 molecular_functionGO:0035663 Toll-like receptor 2 binding ISO
 molecular_functionGO:0042802 identical protein binding ISO
 molecular_functionGO:0042803 protein homodimerization activity IDA
 molecular_functionGO:0046982 protein heterodimerization activity ISO


Pathways (from Reactome)
Pathway description
No match


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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