11816


Mus musculus (NCBI)

Features
Gene ID: 11816
  
Biological name :
  
Synonyms : AI255918|Apo-E / Apoe / apolipoprotein E
  
Possible biological names infered from orthology :
  
Species: Mus musculus (NCBI)
  
Chr. number:
Strand:
Band:
Gene start:
Gene end:
  
Corresponding Affymetrix probe sets: 1432466_a_at (Mouse Genome 430 2.0 Array)   
  
Cross references: RefSeq - 163644329
RefSeq - 802084029
RefSeq - 803378411
RefSeq - 803378413
RefSeq - NC_000073.6
RefSeq - NP_001292748.1
RefSeq - NP_001292772.1
RefSeq - NP_001292773.1
RefSeq - NP_033826.2
RefSeq - NM_001305819.1
RefSeq - NM_001305843.1
RefSeq - NM_001305844.1
RefSeq - NM_009696.4
  
See co-cited genes in PubMed
Warning: Please see the Ensembl gene model ENSMUSG00000002985 to get all the annotations available for this gene.


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0001937 negative regulation of endothelial cell proliferation ISO
 biological_processGO:0002021 response to dietary excess IMP
 biological_processGO:0006629 lipid metabolic process IGI
 biological_processGO:0006641 triglyceride metabolic process ISO
 biological_processGO:0006695 cholesterol biosynthetic process IBA
 biological_processGO:0006707 cholesterol catabolic process IMP
 biological_processGO:0006869 lipid transport ISO
 biological_processGO:0006874 cellular calcium ion homeostasis IDA
 biological_processGO:0006898 receptor-mediated endocytosis ISO
 biological_processGO:0006979 response to oxidative stress IMP
 biological_processGO:0007186 G-protein coupled receptor signaling pathway ISO
 biological_processGO:0007263 nitric oxide mediated signal transduction ISO
 biological_processGO:0007568 aging ISO
 biological_processGO:0007616 long-term memory ISO
 biological_processGO:0008104 protein localization IMP
 biological_processGO:0008203 cholesterol metabolic process ISO
 biological_processGO:0010468 regulation of gene expression IMP
 biological_processGO:0010544 negative regulation of platelet activation ISO
 biological_processGO:0010629 negative regulation of gene expression IMP
 biological_processGO:0010873 positive regulation of cholesterol esterification ISO
 biological_processGO:0010875 positive regulation of cholesterol efflux ISO
 biological_processGO:0010877 lipid transport involved in lipid storage IMP
 biological_processGO:0010976 positive regulation of neuron projection development ISO
 biological_processGO:0010977 negative regulation of neuron projection development ISO
 biological_processGO:0015909 long-chain fatty acid transport ISO
 biological_processGO:0017038 protein import ISO
 biological_processGO:0019068 virion assembly ISO
 biological_processGO:0019433 triglyceride catabolic process IBA
 biological_processGO:0019934 cGMP-mediated signaling ISO
 biological_processGO:0030195 negative regulation of blood coagulation ISO
 biological_processGO:0031102 neuron projection regeneration IBA
 biological_processGO:0031103 axon regeneration IGI
 biological_processGO:0032269 negative regulation of cellular protein metabolic process ISO
 biological_processGO:0032374 regulation of cholesterol transport IBA
 biological_processGO:0032462 regulation of protein homooligomerization ISO
 biological_processGO:0032489 regulation of Cdc42 protein signal transduction ISO
 biological_processGO:0032805 positive regulation of low-density lipoprotein particle receptor catabolic process ISO
 biological_processGO:0033344 cholesterol efflux ISO
 biological_processGO:0033700 phospholipid efflux ISO
 biological_processGO:0034372 very-low-density lipoprotein particle remodeling ISO
 biological_processGO:0034374 low-density lipoprotein particle remodeling IMP
 biological_processGO:0034375 high-density lipoprotein particle remodeling ISO
 biological_processGO:0034380 high-density lipoprotein particle assembly ISO
 biological_processGO:0034382 chylomicron remnant clearance ISO
 biological_processGO:0034384 high-density lipoprotein particle clearance ISO
 biological_processGO:0034447 very-low-density lipoprotein particle clearance ISO
 biological_processGO:0035641 locomotory exploration behavior ISO
 biological_processGO:0042157 lipoprotein metabolic process ISO
 biological_processGO:0042158 lipoprotein biosynthetic process IGI
 biological_processGO:0042159 lipoprotein catabolic process IMP
 biological_processGO:0042311 vasodilation IMP
 biological_processGO:0042632 cholesterol homeostasis ISO
 biological_processGO:0042982 amyloid precursor protein metabolic process ISO
 biological_processGO:0043407 negative regulation of MAP kinase activity ISO
 biological_processGO:0043524 negative regulation of neuron apoptotic process ISO
 biological_processGO:0043537 negative regulation of blood vessel endothelial cell migration ISO
 biological_processGO:0043691 reverse cholesterol transport ISO
 biological_processGO:0044794 positive regulation by host of viral process ISO
 biological_processGO:0045541 negative regulation of cholesterol biosynthetic process ISO
 biological_processGO:0045773 positive regulation of axon extension ISO
 biological_processGO:0045807 positive regulation of endocytosis ISO
 biological_processGO:0046889 positive regulation of lipid biosynthetic process ISO
 biological_processGO:0048844 artery morphogenesis IGI
 biological_processGO:0050728 negative regulation of inflammatory response IGI
 biological_processGO:0051000 positive regulation of nitric-oxide synthase activity ISO
 biological_processGO:0051044 positive regulation of membrane protein ectodomain proteolysis ISO
 biological_processGO:0051246 regulation of protein metabolic process ISO
 biological_processGO:0051651 maintenance of location in cell IMP
 biological_processGO:0055088 lipid homeostasis IMP
 biological_processGO:0055089 fatty acid homeostasis ISO
 biological_processGO:0060999 positive regulation of dendritic spine development ISO
 biological_processGO:0061771 response to caloric restriction ISO
 biological_processGO:0070328 triglyceride homeostasis IMP
 biological_processGO:0072358 cardiovascular system development IMP
 biological_processGO:0090090 negative regulation of canonical Wnt signaling pathway ISO
 biological_processGO:0090181 regulation of cholesterol metabolic process ISO
 biological_processGO:0090207 regulation of triglyceride metabolic process ISO
 biological_processGO:0090209 negative regulation of triglyceride metabolic process IGI
 biological_processGO:0097006 regulation of plasma lipoprotein particle levels IMP
 biological_processGO:0097113 AMPA glutamate receptor clustering ISO
 biological_processGO:0097114 NMDA glutamate receptor clustering ISO
 biological_processGO:1900221 regulation of amyloid-beta clearance ISO
 biological_processGO:1900272 negative regulation of long-term synaptic potentiation ISO
 biological_processGO:1901215 negative regulation of neuron death ISO
 biological_processGO:1901628 positive regulation of postsynaptic membrane organization ISO
 biological_processGO:1901630 negative regulation of presynaptic membrane organization ISO
 biological_processGO:1902430 negative regulation of amyloid-beta formation ISO
 biological_processGO:1902952 positive regulation of dendritic spine maintenance ISO
 biological_processGO:1902995 positive regulation of phospholipid efflux ISO
 biological_processGO:1903002 positive regulation of lipid transport across blood brain barrier ISO
 biological_processGO:1905855 positive regulation of heparan sulfate binding ISO
 biological_processGO:1905860 positive regulation of heparan sulfate proteoglycan binding ISO
 biological_processGO:1905890 regulation of cellular response to very-low-density lipoprotein particle stimulus ISO
 biological_processGO:1905906 regulation of amyloid fibril formation ISO
 biological_processGO:2000822 regulation of behavioral fear response ISO
 cellular_componentGO:0005576 extracellular region ISO
 cellular_componentGO:0005615 extracellular space ISO
 cellular_componentGO:0005635 nuclear envelope ISO
 cellular_componentGO:0005737 cytoplasm ISO
 cellular_componentGO:0005764 lysosome ISO
 cellular_componentGO:0005768 endosome ISO
 cellular_componentGO:0005769 early endosome ISO
 cellular_componentGO:0005770 late endosome ISO
 cellular_componentGO:0005783 endoplasmic reticulum ISO
 cellular_componentGO:0005794 Golgi apparatus ISO
 cellular_componentGO:0005874 microtubule ISO
 cellular_componentGO:0005886 plasma membrane ISO
 cellular_componentGO:0009986 cell surface ISO
 cellular_componentGO:0030425 dendrite ISO
 cellular_componentGO:0031232 extrinsic component of external side of plasma membrane ISO
 cellular_componentGO:0034361 very-low-density lipoprotein particle ISO
 cellular_componentGO:0034362 low-density lipoprotein particle ISO
 cellular_componentGO:0034363 intermediate-density lipoprotein particle ISO
 cellular_componentGO:0034364 high-density lipoprotein particle ISO
 cellular_componentGO:0034365 discoidal high-density lipoprotein particle ISO
 cellular_componentGO:0042627 chylomicron ISO
 cellular_componentGO:0043025 neuronal cell body ISO
 cellular_componentGO:1990777 lipoprotein particle ISO
 molecular_functionGO:0001540 amyloid-beta binding ISO
 molecular_functionGO:0005102 signaling receptor binding ISO
 molecular_functionGO:0005319 lipid transporter activity ISO
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0005543 phospholipid binding ISO
 molecular_functionGO:0008201 heparin binding ISO
 molecular_functionGO:0008289 lipid binding ISO
 molecular_functionGO:0015485 cholesterol binding IBA
 molecular_functionGO:0016209 antioxidant activity ISO
 molecular_functionGO:0017127 cholesterol transporter activity IDA
 molecular_functionGO:0042802 identical protein binding ISO
 molecular_functionGO:0042803 protein homodimerization activity ISO
 molecular_functionGO:0044877 protein-containing complex binding ISO
 molecular_functionGO:0046848 hydroxyapatite binding ISO
 molecular_functionGO:0046911 metal chelating activity ISO
 molecular_functionGO:0046983 protein dimerization activity ISO
 molecular_functionGO:0048156 tau protein binding ISO
 molecular_functionGO:0050750 low-density lipoprotein particle receptor binding ISO
 molecular_functionGO:0060228 phosphatidylcholine-sterol O-acyltransferase activator activity ISO
 molecular_functionGO:0070326 very-low-density lipoprotein particle receptor binding ISO
 molecular_functionGO:0071813 lipoprotein particle binding IDA


Pathways (from Reactome)
Pathway description
No match


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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