11820


Mus musculus (NCBI)

Features
Gene ID: 11820
  
Biological name :
  
Synonyms : Abeta|Abpp|Adap|Ag|Cvap|E030013M08Rik|betaApp / amyloid beta (A4) precursor protein / App
  
Possible biological names infered from orthology :
  
Species: Mus musculus (NCBI)
  
Chr. number:
Strand:
Band:
Gene start:
Gene end:
  
Corresponding Affymetrix probe sets: 1420621_a_at (Mouse Genome 430 2.0 Array)   1427442_a_at (Mouse Genome 430 2.0 Array)   1438373_at (Mouse Genome 430 2.0 Array)   1438374_x_at (Mouse Genome 430 2.0 Array)   
  
Cross references: RefSeq - 311893401
RefSeq - 311893404
RefSeq - 311893406
RefSeq - 311893408
RefSeq - 47271504
RefSeq - 568997207
RefSeq - 568997209
RefSeq - NC_000082.6
RefSeq - NP_001185752.1
RefSeq - NP_001185753.1
RefSeq - NP_001185754.1
RefSeq - NP_001185755.1
RefSeq - NP_031497.2
RefSeq - XP_006522936.1
RefSeq - XP_006522937.1
RefSeq - NM_001198823.1
RefSeq - NM_001198824.1
RefSeq - NM_001198825.1
RefSeq - NM_001198826.1
RefSeq - NM_007471.3
RefSeq - XM_006522874.1
RefSeq - XM_006522873.2
  
See co-cited genes in PubMed
Warning: Please see the Ensembl gene model ENSMUSG00000022892 to get all the annotations available for this gene.


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0001934 positive regulation of protein phosphorylation ISO
 biological_processGO:0001967 suckling behavior IGI
 biological_processGO:0002265 astrocyte activation involved in immune response ISO
 biological_processGO:0006378 mRNA polyadenylation IDA
 biological_processGO:0006417 regulation of translation IDA
 biological_processGO:0006468 protein phosphorylation IMP
 biological_processGO:0006878 cellular copper ion homeostasis IMP
 biological_processGO:0006897 endocytosis IMP
 biological_processGO:0006915 apoptotic process IEA
 biological_processGO:0006979 response to oxidative stress IGI
 biological_processGO:0007155 cell adhesion IEA
 biological_processGO:0007176 regulation of epidermal growth factor-activated receptor activity IGI
 biological_processGO:0007219 Notch signaling pathway IEA
 biological_processGO:0007399 nervous system development IEA
 biological_processGO:0007409 axonogenesis IMP
 biological_processGO:0007611 learning or memory ISO
 biological_processGO:0007612 learning ISO
 biological_processGO:0007613 memory TAS
 biological_processGO:0007617 mating behavior IGI
 biological_processGO:0007626 locomotory behavior IGI
 biological_processGO:0008088 axo-dendritic transport IMP
 biological_processGO:0008203 cholesterol metabolic process IMP
 biological_processGO:0008285 negative regulation of cell proliferation ISO
 biological_processGO:0008344 adult locomotory behavior IMP
 biological_processGO:0008542 visual learning IMP
 biological_processGO:0009987 cellular process ISO
 biological_processGO:0010466 negative regulation of peptidase activity IEA
 biological_processGO:0010468 regulation of gene expression ISO
 biological_processGO:0010628 positive regulation of gene expression ISO
 biological_processGO:0010629 negative regulation of gene expression ISO
 biological_processGO:0010800 positive regulation of peptidyl-threonine phosphorylation ISO
 biological_processGO:0010971 positive regulation of G2/M transition of mitotic cell cycle IMP
 biological_processGO:0014005 microglia development ISO
 biological_processGO:0016199 axon midline choice point recognition IMP
 biological_processGO:0016322 neuron remodeling IMP
 biological_processGO:0016358 dendrite development IMP
 biological_processGO:0030198 extracellular matrix organization IGI
 biological_processGO:0030900 forebrain development IMP
 biological_processGO:0031175 neuron projection development IDA
 biological_processGO:0032092 positive regulation of protein binding ISO
 biological_processGO:0032640 tumor necrosis factor production ISO
 biological_processGO:0033138 positive regulation of peptidyl-serine phosphorylation ISO
 biological_processGO:0035235 ionotropic glutamate receptor signaling pathway IMP
 biological_processGO:0040014 regulation of multicellular organism growth IMP
 biological_processGO:0042327 positive regulation of phosphorylation ISO
 biological_processGO:0043393 regulation of protein binding IMP
 biological_processGO:0045665 negative regulation of neuron differentiation IGI
 biological_processGO:0045931 positive regulation of mitotic cell cycle IMP
 biological_processGO:0045944 positive regulation of transcription by RNA polymerase II ISO
 biological_processGO:0046330 positive regulation of JNK cascade ISO
 biological_processGO:0048143 astrocyte activation ISO
 biological_processGO:0048169 regulation of long-term neuronal synaptic plasticity ISO
 biological_processGO:0048669 collateral sprouting in absence of injury IGI
 biological_processGO:0050730 regulation of peptidyl-tyrosine phosphorylation ISO
 biological_processGO:0050803 regulation of synapse structure or activity IMP
 biological_processGO:0050808 synapse organization ISO
 biological_processGO:0050885 neuromuscular process controlling balance IGI
 biological_processGO:0051091 positive regulation of DNA-binding transcription factor activity ISO
 biological_processGO:0051092 positive regulation of NF-kappaB transcription factor activity ISO
 biological_processGO:0051124 synaptic growth at neuromuscular junction IGI
 biological_processGO:0051247 positive regulation of protein metabolic process ISO
 biological_processGO:0051260 protein homooligomerization ISO
 biological_processGO:0051402 neuron apoptotic process ISO
 biological_processGO:0051563 smooth endoplasmic reticulum calcium ion homeostasis IGI
 biological_processGO:0060291 long-term synaptic potentiation TAS
 biological_processGO:0061890 positive regulation of astrocyte activation ISO
 biological_processGO:0070374 positive regulation of ERK1 and ERK2 cascade ISO
 biological_processGO:0071874 cellular response to norepinephrine stimulus ISO
 biological_processGO:0090647 modulation of age-related behavioral decline ISO
 biological_processGO:0098815 modulation of excitatory postsynaptic potential ISO
 biological_processGO:0150003 regulation of spontaneous synaptic transmission ISO
 biological_processGO:1900272 negative regulation of long-term synaptic potentiation ISO
 biological_processGO:1900273 positive regulation of long-term synaptic potentiation ISO
 biological_processGO:1901224 positive regulation of NIK/NF-kappaB signaling ISO
 biological_processGO:1902004 positive regulation of amyloid-beta formation ISO
 biological_processGO:1903980 positive regulation of microglial cell activation ISO
 biological_processGO:1904646 cellular response to amyloid-beta ISO
 biological_processGO:1905908 positive regulation of amyloid fibril formation ISO
 biological_processGO:1990000 amyloid fibril formation ISO
 biological_processGO:1990535 neuron projection maintenance ISO
 biological_processGO:2000406 positive regulation of T cell migration ISO
 cellular_componentGO:0005615 extracellular space ISO
 cellular_componentGO:0005641 nuclear envelope lumen ISO
 cellular_componentGO:0005737 cytoplasm ISO
 cellular_componentGO:0005768 endosome ISO
 cellular_componentGO:0005791 rough endoplasmic reticulum ISO
 cellular_componentGO:0005794 Golgi apparatus ISO
 cellular_componentGO:0005886 plasma membrane ISO
 cellular_componentGO:0005905 clathrin-coated pit IEA
 cellular_componentGO:0005911 cell-cell junction IDA
 cellular_componentGO:0009986 cell surface ISO
 cellular_componentGO:0016020 membrane TAS
 cellular_componentGO:0016021 integral component of membrane IDA
 cellular_componentGO:0030134 COPII-coated ER to Golgi transport vesicle IDA
 cellular_componentGO:0030424 axon ISO
 cellular_componentGO:0030426 growth cone ISO
 cellular_componentGO:0031410 cytoplasmic vesicle IDA
 cellular_componentGO:0031594 neuromuscular junction IDA
 cellular_componentGO:0035253 ciliary rootlet IDA
 cellular_componentGO:0043005 neuron projection ISO
 cellular_componentGO:0043235 receptor complex ISO
 cellular_componentGO:0044304 main axon ISO
 cellular_componentGO:0045121 membrane raft ISO
 cellular_componentGO:0045177 apical part of cell IDA
 cellular_componentGO:0048471 perinuclear region of cytoplasm ISO
 cellular_componentGO:0051233 spindle midzone IDA
 cellular_componentGO:0097449 astrocyte projection ISO
 cellular_componentGO:1990761 growth cone lamellipodium ISO
 cellular_componentGO:1990812 growth cone filopodium ISO
 molecular_functionGO:0003677 DNA binding IDA
 molecular_functionGO:0004867 serine-type endopeptidase inhibitor activity ISO
 molecular_functionGO:0005102 signaling receptor binding ISO
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0008201 heparin binding IEA
 molecular_functionGO:0016504 peptidase activator activity ISO
 molecular_functionGO:0019899 enzyme binding ISO
 molecular_functionGO:0030414 peptidase inhibitor activity IEA
 molecular_functionGO:0042802 identical protein binding ISO
 molecular_functionGO:0046872 metal ion binding IEA
 molecular_functionGO:0046914 transition metal ion binding IEA
 molecular_functionGO:0051425 PTB domain binding ISO
 molecular_functionGO:0070851 growth factor receptor binding ISO


Pathways (from Reactome)
Pathway description
No match


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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