11847


Mus musculus (NCBI)
regulationprocessimmuneresponseproductionsecretionactivityinterleukin-bindingargininestriatedmusclecontractiontumornecrosisfactornitric-oxidesynthasechemokinec-cmotifligandcd-positivealpha-betatcellhydrolaseionurea

Features
Gene ID: 11847
  
Biological name :
  
Synonyms : AII|AU022422 / Arg2 / arginase type II
  
Possible biological names infered from orthology :
  
Species: Mus musculus (NCBI)
  
Chr. number:
Strand:
Band:
Gene start:
Gene end:
  
Corresponding Affymetrix probe sets: 1418847_at (Mouse Genome 430 2.0 Array)   1438841_s_at (Mouse Genome 430 2.0 Array)   
  
Cross references: RefSeq - 6753110
RefSeq - NC_000078.6
RefSeq - NP_033835.1
RefSeq - NM_009705.3
  
See co-cited genes in PubMed
Warning: Please see the Ensembl gene model ENSMUSG00000021125 to get all the annotations available for this gene.


Gene Ontology (GO)
nitrogen compound metabolic processbiosynthetic processcellular metabolic processsmall molecule metabolic processorganic substance metabolic processanatomical structure developmentimmune responseprimary metabolic processsystem processresponse to chemicalestablishment of localizationcatabolic processcytokine productionresponse to stressmacromolecule localizationregulation of molecular functionresponse to external stimulusresponse to biotic stimuluscell deathcell activationcell adhesionleukocyte proliferationcellular developmental processcellular response to stimulusagingnitrogen compound metabolic processbiosynthetic processcellular metabolic processsmall molecule metabolic processorganic substance metabolic processanatomical structure developmentimmune responseprimary metabolic processsystem processresponse to chemicalestablishment of localizationcatabolic processcytokine productionresponse to stressmacromolecule localizationregulation of molecular functionresponse to external stimulusresponse to biotic stimuluscell deathcell activationcell adhesionleukocyte proliferationcellular developmental processcellular response to stimulusagingnitrogen compound metabolic processbiosynthetic processcellular metabolic processsmall molecule metabolic processorganic substance metabolic processanatomical structure developmentimmune responseprimary metabolic processsystem processresponse to chemicalestablishment of localizationcatabolic processcytokine productionresponse to stressmacromolecule localizationregulation of molecular functionresponse to external stimulusresponse to biotic stimuluscell deathcell activationcell adhesionleukocyte proliferationcellular developmental processcellular response to stimulusagingnitrogen compound metabolic processbiosynthetic processcellular metabolic processsmall molecule metabolic processorganic substance metabolic processanatomical structure developmentimmune responseprimary metabolic processsystem processresponse to chemicalestablishment of localizationcatabolic processcytokine productionresponse to stressmacromolecule localizationregulation of molecular functionresponse to external stimulusresponse to biotic stimuluscell deathcell activationcell adhesionleukocyte proliferationcellular developmental processcellular response to stimulusagingnitrogen compound metabolic processbiosynthetic processcellular metabolic processsmall molecule metabolic processorganic substance metabolic processanatomical structure developmentimmune responseprimary metabolic processsystem processresponse to chemicalestablishment of localizationcatabolic processcytokine productionresponse to stressmacromolecule localizationregulation of molecular functionresponse to external stimulusresponse to biotic stimuluscell deathcell activationcell adhesionleukocyte proliferationcellular developmental processcellular response to stimulusagingnitrogen compound metabolic processbiosynthetic processcellular metabolic processsmall molecule metabolic processorganic substance metabolic processanatomical structure developmentimmune responseprimary metabolic processsystem processresponse to chemicalestablishment of localizationcatabolic processcytokine productionresponse to stressmacromolecule localizationregulation of molecular functionresponse to external stimulusresponse to biotic stimuluscell deathcell activationcell adhesionleukocyte proliferationcellular developmental processcellular response to stimulusagingnitrogen compound metabolic processbiosynthetic processcellular metabolic processsmall molecule metabolic processorganic substance metabolic processanatomical structure developmentimmune responseprimary metabolic processsystem processresponse to chemicalestablishment of localizationcatabolic processcytokine productionresponse to stressmacromolecule localizationregulation of molecular functionresponse to external stimulusresponse to biotic stimuluscell deathcell activationcell adhesionleukocyte proliferationcellular developmental processcellular response to stimulusagingnitrogen compound metabolic processbiosynthetic processcellular metabolic processsmall molecule metabolic processorganic substance metabolic processanatomical structure developmentimmune responseprimary metabolic processsystem processresponse to chemicalestablishment of localizationcatabolic processcytokine productionresponse to stressmacromolecule localizationregulation of molecular functionresponse to external stimulusresponse to biotic stimuluscell deathcell activationcell adhesionleukocyte proliferationcellular developmental processcellular response to stimulusagingnitrogen compound metabolic processbiosynthetic processcellular metabolic processsmall molecule metabolic processorganic substance metabolic processanatomical structure developmentimmune responseprimary metabolic processsystem processresponse to chemicalestablishment of localizationcatabolic processcytokine productionresponse to stressmacromolecule localizationregulation of molecular functionresponse to external stimulusresponse to biotic stimuluscell deathcell activationcell adhesionleukocyte proliferationcellular developmental processcellular response to stimulusagingnitrogen compound metabolic processbiosynthetic processcellular metabolic processsmall molecule metabolic processorganic substance metabolic processanatomical structure developmentimmune responseprimary metabolic processsystem processresponse to chemicalestablishment of localizationcatabolic processcytokine productionresponse to stressmacromolecule localizationregulation of molecular functionresponse to external stimulusresponse to biotic stimuluscell deathcell activationcell adhesionleukocyte proliferationcellular developmental processcellular response to stimulusagingnitronitrogen compound metabolic processbiosybiosynthetic processcellucellular metabolic processsmallsmall molecule metabolic processorganorganic substance metabolic processanatoanatomical structure developmentimmunimmune responseprimaprimary metabolic processsystesystem processresporesponse to chemicalestabestablishment of localizationcatabcatabolic processcytokcytokine productionresporesponse to stressmacromacromolecule localizationregulregulation of molecular functionresporesponse to external stimulusresporesponse to biotic stimuluscell cell deathcell cell activationcell cell adhesionleukoleukocyte proliferationcellucellular developmental processcellucellular response to stimulusagingaging
hydrolase activityion bindingprotein bindinghydrolase activityion bindingprotein bindinghydrolase activityion bindingprotein bindinghydrolase activityion bindingprotein bindinghydrolase activityion bindingprotein bindinghydrolase activityion bindingprotein bindinghydrolase activityion bindingprotein bindinghydrolase activityion bindingprotein bindinghydrolase activityion bindingprotein bindinghydrolase activityion bindingprotein bindinghydrolase activityhydrolase activityion bindingion bindingprotein bindingprotein binding
cellorganellecellorganellecellorganellecellorganellecellorganellecellorganellecellorganellecellorganellecellorganellecellorganellecellcellorganelleorganelle
TypeGO IDTermEv.Code
 biological_processGO:0000050 urea cycle IEA
 biological_processGO:0001657 ureteric bud development IEP
 biological_processGO:0002250 adaptive immune response IEA
 biological_processGO:0002376 immune system process IEA
 biological_processGO:0002829 negative regulation of type 2 immune response IMP
 biological_processGO:0006525 arginine metabolic process ISO
 biological_processGO:0006941 striated muscle contraction IMP
 biological_processGO:0010963 regulation of L-arginine import ISO
 biological_processGO:0019547 arginine catabolic process to ornithine ISO
 biological_processGO:0032720 negative regulation of tumor necrosis factor production ISO
 biological_processGO:0045087 innate immune response IEA
 biological_processGO:0045988 negative regulation of striated muscle contraction ISO
 biological_processGO:0050706 regulation of interleukin-1 beta secretion IMP
 biological_processGO:0051001 negative regulation of nitric-oxide synthase activity ISO
 biological_processGO:0071641 negative regulation of macrophage inflammatory protein 1 alpha production IMP
 biological_processGO:0071644 negative regulation of chemokine (C-C motif) ligand 4 production IMP
 biological_processGO:0071650 negative regulation of chemokine (C-C motif) ligand 5 production IMP
 biological_processGO:1900425 negative regulation of defense response to bacterium IMP
 biological_processGO:1903426 regulation of reactive oxygen species biosynthetic process IMP
 biological_processGO:1904468 negative regulation of tumor necrosis factor secretion IMP
 biological_processGO:1905077 negative regulation of interleukin-17 secretion IMP
 biological_processGO:1905403 negative regulation of activated CD8-positive, alpha-beta T cell apoptotic process IMP
 biological_processGO:2000562 negative regulation of CD4-positive, alpha-beta T cell proliferation IMP
 biological_processGO:2000666 negative regulation of interleukin-13 secretion IMP
 biological_processGO:2000774 positive regulation of cellular senescence ISO
 cellular_componentGO:0005737 cytoplasm IBA
 cellular_componentGO:0005739 mitochondrion ISO
 cellular_componentGO:0005829 cytosol IBA
 molecular_functionGO:0004053 arginase activity ISO
 molecular_functionGO:0016787 hydrolase activity IEA
 molecular_functionGO:0016813 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amidines IEA
 molecular_functionGO:0030145 manganese ion binding IBA
 molecular_functionGO:0046872 metal ion binding IEA
 molecular_functionGO:0050998 nitric-oxide synthase binding ISO


Pathways (from Reactome)
Pathway description
No match


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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