1191


Homo sapiens (NCBI)

Features
Gene ID: 1191
  
Biological name :
  
Synonyms : AAG4|APO-J|APOJ|CLI|CLU1|CLU2|KUB1|NA1/NA2|SGP-2|SGP2|SP-40|TRPM-2|TRPM2 / CLU / clusterin
  
Possible biological names infered from orthology :
  
Species: Homo sapiens (NCBI)
  
Chr. number:
Strand:
Band:
Gene start:
Gene end:
  
Corresponding Affymetrix probe sets: 1559228_at (Human Genome U133 Plus 2.0 Array)   208791_at (Human Genome U133 Plus 2.0 Array)   208792_s_at (Human Genome U133 Plus 2.0 Array)   222043_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: RefSeq - XP_006716347.1
RefSeq - 578815184
RefSeq - NC_000008.11
RefSeq - NG_027845.1
RefSeq - NP_001822.3
RefSeq - 355594753
RefSeq - NR_038335.1
RefSeq - NR_045494.1
RefSeq - NM_001831.3
RefSeq - XM_006716284.3
  
See co-cited genes in PubMed
Warning: Please see the Ensembl gene model ENSG00000120885 to get all the annotations available for this gene.


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0000902 cell morphogenesis IDA
 biological_processGO:0001774 microglial cell activation IDA
 biological_processGO:0001836 release of cytochrome c from mitochondria IC
 biological_processGO:0002576 platelet degranulation TAS
 biological_processGO:0006629 lipid metabolic process NAS
 biological_processGO:0006956 complement activation TAS
 biological_processGO:0006958 complement activation, classical pathway IEA
 biological_processGO:0009615 response to virus IEP
 biological_processGO:0010628 positive regulation of gene expression ISS
 biological_processGO:0017038 protein import IDA
 biological_processGO:0019730 antimicrobial humoral response TAS
 biological_processGO:0030449 regulation of complement activation TAS
 biological_processGO:0032286 central nervous system myelin maintenance IMP
 biological_processGO:0032436 positive regulation of proteasomal ubiquitin-dependent protein catabolic process IMP
 biological_processGO:0032463 negative regulation of protein homooligomerization IMP
 biological_processGO:0032464 positive regulation of protein homooligomerization IDA
 biological_processGO:0032760 positive regulation of tumor necrosis factor production IDA
 biological_processGO:0042981 regulation of apoptotic process IBA
 biological_processGO:0043691 reverse cholesterol transport TAS
 biological_processGO:0045087 innate immune response IEA
 biological_processGO:0045429 positive regulation of nitric oxide biosynthetic process IDA
 biological_processGO:0048260 positive regulation of receptor-mediated endocytosis IGI
 biological_processGO:0050821 protein stabilization IDA
 biological_processGO:0051092 positive regulation of NF-kappaB transcription factor activity IMP
 biological_processGO:0051131 chaperone-mediated protein complex assembly IDA
 biological_processGO:0051788 response to misfolded protein IDA
 biological_processGO:0060548 negative regulation of cell death TAS
 biological_processGO:0061077 chaperone-mediated protein folding IDA
 biological_processGO:0061518 microglial cell proliferation IDA
 biological_processGO:0061740 protein targeting to lysosome involved in chaperone-mediated autophagy IC
 biological_processGO:0061741 chaperone-mediated protein transport involved in chaperone-mediated autophagy IC
 biological_processGO:0090201 negative regulation of release of cytochrome c from mitochondria TAS
 biological_processGO:1900221 regulation of amyloid-beta clearance IDA
 biological_processGO:1901214 regulation of neuron death IMP
 biological_processGO:1901216 positive regulation of neuron death ISS
 biological_processGO:1902004 positive regulation of amyloid-beta formation ISS
 biological_processGO:1902230 negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage IMP
 biological_processGO:1902430 negative regulation of amyloid-beta formation IDA
 biological_processGO:1902847 regulation of neuronal signal transduction IMP
 biological_processGO:1902949 positive regulation of tau-protein kinase activity IMP
 biological_processGO:1902998 positive regulation of neurofibrillary tangle assembly IMP
 biological_processGO:1903573 negative regulation of response to endoplasmic reticulum stress IMP
 biological_processGO:1905892 negative regulation of cellular response to thapsigargin IMP
 biological_processGO:1905895 negative regulation of cellular response to tunicamycin IMP
 biological_processGO:1905907 negative regulation of amyloid fibril formation TAS
 biological_processGO:1905908 positive regulation of amyloid fibril formation TAS
 biological_processGO:2000060 positive regulation of ubiquitin-dependent protein catabolic process IMP
 cellular_componentGO:0005576 extracellular region TAS
 cellular_componentGO:0005615 extracellular space IDA
 cellular_componentGO:0005622 intracellular TAS
 cellular_componentGO:0005634 nucleus IDA
 cellular_componentGO:0005737 cytoplasm IDA
 cellular_componentGO:0005739 mitochondrion IDA
 cellular_componentGO:0005783 endoplasmic reticulum IEA
 cellular_componentGO:0005794 Golgi apparatus ISS
 cellular_componentGO:0005829 cytosol IEA
 cellular_componentGO:0005856 cytoskeleton IDA
 cellular_componentGO:0009986 cell surface IDA
 cellular_componentGO:0016020 membrane IDA
 cellular_componentGO:0031012 extracellular matrix HDA
 cellular_componentGO:0031093 platelet alpha granule lumen TAS
 cellular_componentGO:0031966 mitochondrial membrane IEA
 cellular_componentGO:0032991 protein-containing complex IDA
 cellular_componentGO:0034366 spherical high-density lipoprotein particle IDA
 cellular_componentGO:0042583 chromaffin granule IEA
 cellular_componentGO:0048471 perinuclear region of cytoplasm IDA
 cellular_componentGO:0062023 collagen-containing extracellular matrix HDA
 cellular_componentGO:0070062 extracellular exosome HDA
 cellular_componentGO:0071944 cell periphery IDA
 cellular_componentGO:0072562 blood microparticle HDA
 cellular_componentGO:0097418 neurofibrillary tangle IDA
 cellular_componentGO:0097440 apical dendrite IDA
 molecular_functionGO:0001540 amyloid-beta binding IPI
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0016887 ATPase activity IDA
 molecular_functionGO:0031625 ubiquitin protein ligase binding IDA
 molecular_functionGO:0044877 protein-containing complex binding IPI
 molecular_functionGO:0048156 tau protein binding IPI
 molecular_functionGO:0050750 low-density lipoprotein particle receptor binding IPI
 molecular_functionGO:0051087 chaperone binding ISS
 molecular_functionGO:0051787 misfolded protein binding IPI


Pathways (from Reactome)
Pathway description
No match


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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