12018


Mus musculus (NCBI)

Features
Gene ID: 12018
  
Biological name :
  
Synonyms : Bak1 / Bak|N-BAK1|N-Bak / BCL2-antagonist/killer 1
  
Possible biological names infered from orthology :
  
Species: Mus musculus (NCBI)
  
Chr. number:
Strand:
Band:
Gene start:
Gene end:
  
Corresponding Affymetrix probe sets: 1418991_at (Mouse Genome 430 2.0 Array)   1425716_s_at (Mouse Genome 430 2.0 Array)   
  
Cross references: RefSeq - 111955302
RefSeq - NC_000083.6
RefSeq - NP_031549.2
RefSeq - NM_007523.3
RefSeq - NR_149749.1
RefSeq - XR_385266.2
  
See co-cited genes in PubMed
Warning: Please see the Ensembl gene model ENSMUSG00000057789 to get all the annotations available for this gene.


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0001776 leukocyte homeostasis IGI
 biological_processGO:0001782 B cell homeostasis IMP
 biological_processGO:0001783 B cell apoptotic process IGI
 biological_processGO:0001836 release of cytochrome c from mitochondria ISO
 biological_processGO:0001974 blood vessel remodeling IGI
 biological_processGO:0002262 myeloid cell homeostasis IGI
 biological_processGO:0002352 B cell negative selection IGI
 biological_processGO:0006915 apoptotic process ISO
 biological_processGO:0006919 activation of cysteine-type endopeptidase activity involved in apoptotic process IMP
 biological_processGO:0008053 mitochondrial fusion IGI
 biological_processGO:0008283 cell proliferation IDA
 biological_processGO:0008285 negative regulation of cell proliferation ISO
 biological_processGO:0008630 intrinsic apoptotic signaling pathway in response to DNA damage IMP
 biological_processGO:0008635 activation of cysteine-type endopeptidase activity involved in apoptotic process by cytochrome c IMP
 biological_processGO:0009620 response to fungus IMP
 biological_processGO:0010046 response to mycotoxin IMP
 biological_processGO:0010248 establishment or maintenance of transmembrane electrochemical gradient ISO
 biological_processGO:0010332 response to gamma radiation IMP
 biological_processGO:0010524 positive regulation of calcium ion transport into cytosol IGI
 biological_processGO:0010629 negative regulation of gene expression ISO
 biological_processGO:0032471 negative regulation of endoplasmic reticulum calcium ion concentration IGI
 biological_processGO:0033137 negative regulation of peptidyl-serine phosphorylation IGI
 biological_processGO:0034644 cellular response to UV ISO
 biological_processGO:0035108 limb morphogenesis IGI
 biological_processGO:0042981 regulation of apoptotic process IEA
 biological_processGO:0043065 positive regulation of apoptotic process ISO
 biological_processGO:0043496 regulation of protein homodimerization activity ISO
 biological_processGO:0043497 regulation of protein heterodimerization activity ISO
 biological_processGO:0044346 fibroblast apoptotic process IMP
 biological_processGO:0045862 positive regulation of proteolysis ISO
 biological_processGO:0046902 regulation of mitochondrial membrane permeability ISO
 biological_processGO:0048597 post-embryonic camera-type eye morphogenesis IGI
 biological_processGO:0048872 homeostasis of number of cells IGI
 biological_processGO:0051726 regulation of cell cycle IGI
 biological_processGO:0051881 regulation of mitochondrial membrane potential ISO
 biological_processGO:0060068 vagina development IGI
 biological_processGO:0070059 intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress IGI
 biological_processGO:0070242 thymocyte apoptotic process IGI
 biological_processGO:0090200 positive regulation of release of cytochrome c from mitochondria ISO
 biological_processGO:0097190 apoptotic signaling pathway ISO
 biological_processGO:0097192 extrinsic apoptotic signaling pathway in absence of ligand IGI
 biological_processGO:0097202 activation of cysteine-type endopeptidase activity ISO
 biological_processGO:1900103 positive regulation of endoplasmic reticulum unfolded protein response ISO
 biological_processGO:1902262 apoptotic process involved in blood vessel morphogenesis IGI
 cellular_componentGO:0005622 intracellular IDA
 cellular_componentGO:0005739 mitochondrion ISO
 cellular_componentGO:0005741 mitochondrial outer membrane IBA
 cellular_componentGO:0005783 endoplasmic reticulum IDA
 cellular_componentGO:0005829 cytosol ISO
 cellular_componentGO:0016020 membrane ISO
 cellular_componentGO:0016021 integral component of membrane IEA
 cellular_componentGO:0031307 integral component of mitochondrial outer membrane IDA
 cellular_componentGO:0031966 mitochondrial membrane IDA
 cellular_componentGO:0046930 pore complex ISO
 cellular_componentGO:0097145 BAK complex ISO
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0031072 heat shock protein binding ISO
 molecular_functionGO:0042802 identical protein binding ISO
 molecular_functionGO:0042803 protein homodimerization activity ISO
 molecular_functionGO:0044325 ion channel binding ISO
 molecular_functionGO:0046872 metal ion binding IEA
 molecular_functionGO:0046982 protein heterodimerization activity ISO
 molecular_functionGO:0051087 chaperone binding ISO
 molecular_functionGO:0051400 BH domain binding ISO


Pathways (from Reactome)
Pathway description
No match


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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