12028


Mus musculus (NCBI)

Features
Gene ID: 12028
  
Biological name :
  
Synonyms : Bax / BCL2-associated X protein
  
Possible biological names infered from orthology :
  
Species: Mus musculus (NCBI)
  
Chr. number:
Strand:
Band:
Gene start:
Gene end:
  
Corresponding Affymetrix probe sets: 1416837_at (Mouse Genome 430 2.0 Array)   
  
Cross references: RefSeq - XP_011249082.1
RefSeq - 6680770
RefSeq - 755520643
RefSeq - NC_000073.6
RefSeq - NP_031553.1
RefSeq - XP_006540647.1
RefSeq - 568947240
RefSeq - NM_007527.3
RefSeq - XM_011250780.2
RefSeq - XM_006540584.3
  
See co-cited genes in PubMed
Warning: Please see the Ensembl gene model ENSMUSG00000003873 to get all the annotations available for this gene.


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0001541 ovarian follicle development IMP
 biological_processGO:0001764 neuron migration IMP
 biological_processGO:0001776 leukocyte homeostasis IGI
 biological_processGO:0001777 T cell homeostatic proliferation IMP
 biological_processGO:0001782 B cell homeostasis IMP
 biological_processGO:0001783 B cell apoptotic process ISO
 biological_processGO:0001822 kidney development IGI
 biological_processGO:0001836 release of cytochrome c from mitochondria ISO
 biological_processGO:0001844 protein insertion into mitochondrial membrane involved in apoptotic signaling pathway IMP
 biological_processGO:0001974 blood vessel remodeling IGI
 biological_processGO:0002262 myeloid cell homeostasis IGI
 biological_processGO:0002352 B cell negative selection IGI
 biological_processGO:0002358 B cell homeostatic proliferation IMP
 biological_processGO:0002904 positive regulation of B cell apoptotic process IGI
 biological_processGO:0006687 glycosphingolipid metabolic process IMP
 biological_processGO:0006808 regulation of nitrogen utilization IGI
 biological_processGO:0006915 apoptotic process ISO
 biological_processGO:0006919 activation of cysteine-type endopeptidase activity involved in apoptotic process ISO
 biological_processGO:0006974 cellular response to DNA damage stimulus IMP
 biological_processGO:0007007 inner mitochondrial membrane organization ISO
 biological_processGO:0007008 outer mitochondrial membrane organization ISO
 biological_processGO:0007281 germ cell development IGI
 biological_processGO:0007283 spermatogenesis IMP
 biological_processGO:0007399 nervous system development IMP
 biological_processGO:0007548 sex differentiation IMP
 biological_processGO:0008053 mitochondrial fusion ISO
 biological_processGO:0008283 cell proliferation IGI
 biological_processGO:0008285 negative regulation of cell proliferation IMP
 biological_processGO:0008584 male gonad development IMP
 biological_processGO:0008625 extrinsic apoptotic signaling pathway via death domain receptors IDA
 biological_processGO:0008630 intrinsic apoptotic signaling pathway in response to DNA damage IMP
 biological_processGO:0008635 activation of cysteine-type endopeptidase activity involved in apoptotic process by cytochrome c ISO
 biological_processGO:0008637 apoptotic mitochondrial changes ISO
 biological_processGO:0009566 fertilization IGI
 biological_processGO:0009611 response to wounding IMP
 biological_processGO:0009636 response to toxic substance ISO
 biological_processGO:0009651 response to salt stress IGI
 biological_processGO:0009791 post-embryonic development IGI
 biological_processGO:0010212 response to ionizing radiation IMP
 biological_processGO:0010248 establishment or maintenance of transmembrane electrochemical gradient ISO
 biological_processGO:0010332 response to gamma radiation IMP
 biological_processGO:0010524 positive regulation of calcium ion transport into cytosol IGI
 biological_processGO:0021854 hypothalamus development IMP
 biological_processGO:0021987 cerebral cortex development IMP
 biological_processGO:0032091 negative regulation of protein binding ISO
 biological_processGO:0032461 positive regulation of protein oligomerization ISO
 biological_processGO:0032471 negative regulation of endoplasmic reticulum calcium ion concentration IGI
 biological_processGO:0032976 release of matrix enzymes from mitochondria ISO
 biological_processGO:0033137 negative regulation of peptidyl-serine phosphorylation IGI
 biological_processGO:0033599 regulation of mammary gland epithelial cell proliferation IMP
 biological_processGO:0034644 cellular response to UV IGI
 biological_processGO:0035108 limb morphogenesis IGI
 biological_processGO:0035234 ectopic germ cell programmed cell death IMP
 biological_processGO:0042475 odontogenesis of dentin-containing tooth IGI
 biological_processGO:0042981 regulation of apoptotic process IEA
 biological_processGO:0043065 positive regulation of apoptotic process ISO
 biological_processGO:0043281 regulation of cysteine-type endopeptidase activity involved in apoptotic process IMP
 biological_processGO:0043496 regulation of protein homodimerization activity ISO
 biological_processGO:0043497 regulation of protein heterodimerization activity ISO
 biological_processGO:0043523 regulation of neuron apoptotic process IMP
 biological_processGO:0043524 negative regulation of neuron apoptotic process IDA
 biological_processGO:0043525 positive regulation of neuron apoptotic process ISO
 biological_processGO:0043653 mitochondrial fragmentation involved in apoptotic process ISO
 biological_processGO:0045136 development of secondary sexual characteristics IMP
 biological_processGO:0045333 cellular respiration ISO
 biological_processGO:0046666 retinal cell programmed cell death IMP
 biological_processGO:0048087 positive regulation of developmental pigmentation IGI
 biological_processGO:0048147 negative regulation of fibroblast proliferation IMP
 biological_processGO:0048515 spermatid differentiation IMP
 biological_processGO:0048597 post-embryonic camera-type eye morphogenesis IGI
 biological_processGO:0048678 response to axon injury IMP
 biological_processGO:0048872 homeostasis of number of cells IMP
 biological_processGO:0048873 homeostasis of number of cells within a tissue IMP
 biological_processGO:0051259 protein complex oligomerization ISO
 biological_processGO:0051260 protein homooligomerization ISO
 biological_processGO:0051281 positive regulation of release of sequestered calcium ion into cytosol IMP
 biological_processGO:0051402 neuron apoptotic process IMP
 biological_processGO:0051726 regulation of cell cycle IGI
 biological_processGO:0051881 regulation of mitochondrial membrane potential IDA
 biological_processGO:0060011 Sertoli cell proliferation IGI
 biological_processGO:0060041 retina development in camera-type eye IMP
 biological_processGO:0060058 positive regulation of apoptotic process involved in mammary gland involution IMP
 biological_processGO:0060068 vagina development IGI
 biological_processGO:0070059 intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress ISO
 biological_processGO:0070242 thymocyte apoptotic process IGI
 biological_processGO:0070584 mitochondrion morphogenesis IGI
 biological_processGO:0071310 cellular response to organic substance IDA
 biological_processGO:0072332 intrinsic apoptotic signaling pathway by p53 class mediator IMP
 biological_processGO:0090200 positive regulation of release of cytochrome c from mitochondria ISO
 biological_processGO:0097190 apoptotic signaling pathway ISO
 biological_processGO:0097191 extrinsic apoptotic signaling pathway ISO
 biological_processGO:0097192 extrinsic apoptotic signaling pathway in absence of ligand IGI
 biological_processGO:0097193 intrinsic apoptotic signaling pathway ISO
 biological_processGO:0097296 activation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway IMP
 biological_processGO:1900103 positive regulation of endoplasmic reticulum unfolded protein response ISO
 biological_processGO:1902108 regulation of mitochondrial membrane permeability involved in apoptotic process IGI
 biological_processGO:1902110 positive regulation of mitochondrial membrane permeability involved in apoptotic process IGI
 biological_processGO:1902262 apoptotic process involved in blood vessel morphogenesis IGI
 biological_processGO:1902263 apoptotic process involved in embryonic digit morphogenesis IGI
 biological_processGO:1902445 regulation of mitochondrial membrane permeability involved in programmed necrotic cell death IMP
 biological_processGO:1902512 positive regulation of apoptotic DNA fragmentation ISO
 biological_processGO:1990117 B cell receptor apoptotic signaling pathway ISO
 biological_processGO:2001234 negative regulation of apoptotic signaling pathway IGI
 biological_processGO:2001241 positive regulation of extrinsic apoptotic signaling pathway in absence of ligand IDA
 biological_processGO:2001244 positive regulation of intrinsic apoptotic signaling pathway ISO
 cellular_componentGO:0005622 intracellular IDA
 cellular_componentGO:0005634 nucleus ISO
 cellular_componentGO:0005635 nuclear envelope ISO
 cellular_componentGO:0005737 cytoplasm ISO
 cellular_componentGO:0005739 mitochondrion ISO
 cellular_componentGO:0005741 mitochondrial outer membrane ISO
 cellular_componentGO:0005757 mitochondrial permeability transition pore complex ISO
 cellular_componentGO:0005783 endoplasmic reticulum ISO
 cellular_componentGO:0005789 endoplasmic reticulum membrane ISO
 cellular_componentGO:0005829 cytosol ISO
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane ISS
 cellular_componentGO:0031966 mitochondrial membrane ISO
 cellular_componentGO:0046930 pore complex ISO
 cellular_componentGO:0048471 perinuclear region of cytoplasm ISO
 cellular_componentGO:0071944 cell periphery ISO
 cellular_componentGO:0097136 Bcl-2 family protein complex ISO
 cellular_componentGO:0097144 BAX complex ISO
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0008289 lipid binding ISO
 molecular_functionGO:0015267 channel activity ISO
 molecular_functionGO:0030544 Hsp70 protein binding IDA
 molecular_functionGO:0031072 heat shock protein binding ISO
 molecular_functionGO:0042802 identical protein binding ISO
 molecular_functionGO:0042803 protein homodimerization activity ISO
 molecular_functionGO:0044877 protein-containing complex binding ISO
 molecular_functionGO:0046982 protein heterodimerization activity ISO
 molecular_functionGO:0051087 chaperone binding ISO
 molecular_functionGO:0051400 BH domain binding ISO
 molecular_functionGO:0051434 BH3 domain binding ISO


Pathways (from Reactome)
Pathway description
No match


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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