12043


Mus musculus (NCBI)

Features
Gene ID: 12043
  
Biological name :
  
Synonyms : AW986256|Bcl-2|C430015F12Rik|D630044D05Rik|D830018M01Rik / B cell leukemia/lymphoma 2 / Bcl2
  
Possible biological names infered from orthology :
  
Species: Mus musculus (NCBI)
  
Chr. number:
Strand:
Band:
Gene start:
Gene end:
  
Corresponding Affymetrix probe sets: 1422938_at (Mouse Genome 430 2.0 Array)   1437122_at (Mouse Genome 430 2.0 Array)   1440770_at (Mouse Genome 430 2.0 Array)   1443837_x_at (Mouse Genome 430 2.0 Array)   1457687_at (Mouse Genome 430 2.0 Array)   
  
Cross references: RefSeq - NP_033871.2
RefSeq - NP_803129.2
RefSeq - NC_000067.6
RefSeq - 133892547
RefSeq - 133893254
RefSeq - NM_009741.5
RefSeq - NM_177410.3
  
See co-cited genes in PubMed
Warning: Please see the Ensembl gene model ENSMUSG00000057329 to get all the annotations available for this gene.


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0000209 protein polyubiquitination ISO
 biological_processGO:0000902 cell morphogenesis IMP
 biological_processGO:0001503 ossification IMP
 biological_processGO:0001541 ovarian follicle development IMP
 biological_processGO:0001656 metanephros development IMP
 biological_processGO:0001657 ureteric bud development IMP
 biological_processGO:0001658 branching involved in ureteric bud morphogenesis IGI
 biological_processGO:0001662 behavioral fear response IMP
 biological_processGO:0001776 leukocyte homeostasis IMP
 biological_processGO:0001782 B cell homeostasis IMP
 biological_processGO:0001822 kidney development IMP
 biological_processGO:0001836 release of cytochrome c from mitochondria IDA
 biological_processGO:0001952 regulation of cell-matrix adhesion IMP
 biological_processGO:0002260 lymphocyte homeostasis IMP
 biological_processGO:0002320 lymphoid progenitor cell differentiation IMP
 biological_processGO:0002326 B cell lineage commitment IMP
 biological_processGO:0002360 T cell lineage commitment IMP
 biological_processGO:0002520 immune system development IMP
 biological_processGO:0002931 response to ischemia IMP
 biological_processGO:0003014 renal system process IMP
 biological_processGO:0006470 protein dephosphorylation IDA
 biological_processGO:0006582 melanin metabolic process IMP
 biological_processGO:0006808 regulation of nitrogen utilization IGI
 biological_processGO:0006874 cellular calcium ion homeostasis IDA
 biological_processGO:0006915 apoptotic process ISO
 biological_processGO:0006974 cellular response to DNA damage stimulus ISO
 biological_processGO:0006979 response to oxidative stress IMP
 biological_processGO:0007015 actin filament organization IMP
 biological_processGO:0007409 axonogenesis IMP
 biological_processGO:0007569 cell aging IMP
 biological_processGO:0008283 cell proliferation IGI
 biological_processGO:0008284 positive regulation of cell proliferation IMP
 biological_processGO:0008285 negative regulation of cell proliferation IMP
 biological_processGO:0008584 male gonad development IGI
 biological_processGO:0008625 extrinsic apoptotic signaling pathway via death domain receptors ISO
 biological_processGO:0008630 intrinsic apoptotic signaling pathway in response to DNA damage IGI
 biological_processGO:0008631 intrinsic apoptotic signaling pathway in response to oxidative stress IMP
 biological_processGO:0008637 apoptotic mitochondrial changes IDA
 biological_processGO:0009636 response to toxic substance ISO
 biological_processGO:0009791 post-embryonic development IMP
 biological_processGO:0009887 animal organ morphogenesis IMP
 biological_processGO:0010039 response to iron ion ISO
 biological_processGO:0010224 response to UV-B IMP
 biological_processGO:0010332 response to gamma radiation IMP
 biological_processGO:0010468 regulation of gene expression IMP
 biological_processGO:0010506 regulation of autophagy IMP
 biological_processGO:0010507 negative regulation of autophagy IMP
 biological_processGO:0010523 negative regulation of calcium ion transport into cytosol IGI
 biological_processGO:0010559 regulation of glycoprotein biosynthetic process IMP
 biological_processGO:0010667 negative regulation of cardiac muscle cell apoptotic process ISO
 biological_processGO:0014031 mesenchymal cell development IMP
 biological_processGO:0014042 positive regulation of neuron maturation IMP
 biological_processGO:0014911 positive regulation of smooth muscle cell migration IMP
 biological_processGO:0018105 peptidyl-serine phosphorylation IDA
 biological_processGO:0018107 peptidyl-threonine phosphorylation IDA
 biological_processGO:0021747 cochlear nucleus development IMP
 biological_processGO:0022612 gland morphogenesis IMP
 biological_processGO:0022898 regulation of transmembrane transporter activity ISO
 biological_processGO:0030097 hemopoiesis IMP
 biological_processGO:0030183 B cell differentiation IMP
 biological_processGO:0030217 T cell differentiation IMP
 biological_processGO:0030279 negative regulation of ossification IMP
 biological_processGO:0030307 positive regulation of cell growth ISO
 biological_processGO:0030308 negative regulation of cell growth IMP
 biological_processGO:0030318 melanocyte differentiation IMP
 biological_processGO:0030336 negative regulation of cell migration IMP
 biological_processGO:0030890 positive regulation of B cell proliferation ISO
 biological_processGO:0031069 hair follicle morphogenesis IMP
 biological_processGO:0031103 axon regeneration IDA
 biological_processGO:0031647 regulation of protein stability IMP
 biological_processGO:0032469 endoplasmic reticulum calcium ion homeostasis IGI
 biological_processGO:0032835 glomerulus development IMP
 biological_processGO:0032848 negative regulation of cellular pH reduction ISO
 biological_processGO:0032880 regulation of protein localization IMP
 biological_processGO:0033033 negative regulation of myeloid cell apoptotic process IDA
 biological_processGO:0033077 T cell differentiation in thymus IMP
 biological_processGO:0033138 positive regulation of peptidyl-serine phosphorylation IGI
 biological_processGO:0033689 negative regulation of osteoblast proliferation IMP
 biological_processGO:0034097 response to cytokine ISO
 biological_processGO:0035094 response to nicotine ISO
 biological_processGO:0035265 organ growth IMP
 biological_processGO:0040008 regulation of growth IMP
 biological_processGO:0040018 positive regulation of multicellular organism growth IMP
 biological_processGO:0042100 B cell proliferation ISO
 biological_processGO:0042149 cellular response to glucose starvation IDA
 biological_processGO:0042493 response to drug ISO
 biological_processGO:0042542 response to hydrogen peroxide IMP
 biological_processGO:0042981 regulation of apoptotic process IGI
 biological_processGO:0043029 T cell homeostasis IMP
 biological_processGO:0043066 negative regulation of apoptotic process ISS
 biological_processGO:0043067 regulation of programmed cell death IGI
 biological_processGO:0043085 positive regulation of catalytic activity IMP
 biological_processGO:0043375 CD8-positive, alpha-beta T cell lineage commitment IMP
 biological_processGO:0043473 pigmentation IMP
 biological_processGO:0043496 regulation of protein homodimerization activity ISO
 biological_processGO:0043497 regulation of protein heterodimerization activity ISO
 biological_processGO:0043524 negative regulation of neuron apoptotic process ISO
 biological_processGO:0043583 ear development IMP
 biological_processGO:0045069 regulation of viral genome replication IDA
 biological_processGO:0045471 response to ethanol ISO
 biological_processGO:0045636 positive regulation of melanocyte differentiation IMP
 biological_processGO:0045930 negative regulation of mitotic cell cycle IDA
 biological_processGO:0046671 negative regulation of retinal cell programmed cell death IMP
 biological_processGO:0046902 regulation of mitochondrial membrane permeability IDA
 biological_processGO:0048041 focal adhesion assembly IMP
 biological_processGO:0048066 developmental pigmentation IMP
 biological_processGO:0048070 regulation of developmental pigmentation IGI
 biological_processGO:0048087 positive regulation of developmental pigmentation IMP
 biological_processGO:0048536 spleen development IMP
 biological_processGO:0048538 thymus development IMP
 biological_processGO:0048545 response to steroid hormone IMP
 biological_processGO:0048546 digestive tract morphogenesis IMP
 biological_processGO:0048589 developmental growth IMP
 biological_processGO:0048599 oocyte development IMP
 biological_processGO:0048743 positive regulation of skeletal muscle fiber development IMP
 biological_processGO:0048753 pigment granule organization IMP
 biological_processGO:0048873 homeostasis of number of cells within a tissue IMP
 biological_processGO:0050790 regulation of catalytic activity IMP
 biological_processGO:0050853 B cell receptor signaling pathway ISO
 biological_processGO:0051384 response to glucocorticoid IMP
 biological_processGO:0051402 neuron apoptotic process IMP
 biological_processGO:0051607 defense response to virus ISO
 biological_processGO:0051726 regulation of cell cycle IMP
 biological_processGO:0051881 regulation of mitochondrial membrane potential IDA
 biological_processGO:0051924 regulation of calcium ion transport ISO
 biological_processGO:0070059 intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress ISS
 biological_processGO:0071310 cellular response to organic substance IDA
 biological_processGO:0071456 cellular response to hypoxia IDA
 biological_processGO:0072593 reactive oxygen species metabolic process IMP
 biological_processGO:0097192 extrinsic apoptotic signaling pathway in absence of ligand IGI
 biological_processGO:0098609 cell-cell adhesion IMP
 biological_processGO:2000134 negative regulation of G1/S transition of mitotic cell cycle IMP
 biological_processGO:2000378 negative regulation of reactive oxygen species metabolic process IMP
 biological_processGO:2000811 negative regulation of anoikis ISO
 biological_processGO:2001234 negative regulation of apoptotic signaling pathway ISO
 biological_processGO:2001240 negative regulation of extrinsic apoptotic signaling pathway in absence of ligand ISO
 biological_processGO:2001243 negative regulation of intrinsic apoptotic signaling pathway ISO
 cellular_componentGO:0005622 intracellular IDA
 cellular_componentGO:0005634 nucleus ISO
 cellular_componentGO:0005654 nucleoplasm ISO
 cellular_componentGO:0005737 cytoplasm ISO
 cellular_componentGO:0005739 mitochondrion ISO
 cellular_componentGO:0005741 mitochondrial outer membrane ISO
 cellular_componentGO:0005783 endoplasmic reticulum ISO
 cellular_componentGO:0005789 endoplasmic reticulum membrane IDA
 cellular_componentGO:0005829 cytosol ISO
 cellular_componentGO:0016020 membrane ISO
 cellular_componentGO:0016021 integral component of membrane IEA
 cellular_componentGO:0031965 nuclear membrane ISO
 cellular_componentGO:0031966 mitochondrial membrane IDA
 cellular_componentGO:0032991 protein-containing complex ISO
 cellular_componentGO:0043209 myelin sheath IDA
 cellular_componentGO:0046930 pore complex ISO
 cellular_componentGO:0048471 perinuclear region of cytoplasm ISO
 molecular_functionGO:0002020 protease binding ISO
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0008134 transcription factor binding IPI
 molecular_functionGO:0015267 channel activity ISO
 molecular_functionGO:0016248 channel inhibitor activity ISO
 molecular_functionGO:0019903 protein phosphatase binding IDA
 molecular_functionGO:0031625 ubiquitin protein ligase binding ISO
 molecular_functionGO:0042802 identical protein binding ISO
 molecular_functionGO:0042803 protein homodimerization activity ISO
 molecular_functionGO:0046982 protein heterodimerization activity ISO
 molecular_functionGO:0051400 BH domain binding ISO
 molecular_functionGO:0051434 BH3 domain binding ISO
 molecular_functionGO:0051721 protein phosphatase 2A binding IDA


Pathways (from Reactome)
Pathway description
No match


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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