12144


Mus musculus (NCBI)

Features
Gene ID: 12144
  
Biological name :
  
Synonyms : Blm / Bloom syndrome, RecQ like helicase
  
Possible biological names infered from orthology :
  
Species: Mus musculus (NCBI)
  
Chr. number:
Strand:
Band:
Gene start:
Gene end:
  
Corresponding Affymetrix probe sets: 1448953_at (Mouse Genome 430 2.0 Array)   
  
Cross references: RefSeq - 1039777065
RefSeq - 1039777067
RefSeq - 110225360
RefSeq - 226693393
RefSeq - NC_000073.6
RefSeq - NP_001035992.1
RefSeq - NP_031576.4
RefSeq - XP_017177445.1
RefSeq - XP_017177446.1
RefSeq - XM_017321956.1
RefSeq - NM_001042527.2
RefSeq - NM_007550.4
RefSeq - XM_017321957.1
RefSeq - XR_001785468.1
  
See co-cited genes in PubMed
Warning: Please see the Ensembl gene model ENSMUSG00000030528 to get all the annotations available for this gene.


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0000079 regulation of cyclin-dependent protein serine/threonine kinase activity ISO
 biological_processGO:0000712 resolution of meiotic recombination intermediates IBA
 biological_processGO:0000723 telomere maintenance IGI
 biological_processGO:0000724 double-strand break repair via homologous recombination IBA
 biological_processGO:0000729 DNA double-strand break processing ISO
 biological_processGO:0000731 DNA synthesis involved in DNA repair IBA
 biological_processGO:0000732 strand displacement IBA
 biological_processGO:0006260 DNA replication IMP
 biological_processGO:0006281 DNA repair IDA
 biological_processGO:0006303 double-strand break repair via nonhomologous end joining IBA
 biological_processGO:0006310 DNA recombination IEA
 biological_processGO:0006974 cellular response to DNA damage stimulus ISO
 biological_processGO:0007095 mitotic G2 DNA damage checkpoint ISO
 biological_processGO:0010165 response to X-ray ISO
 biological_processGO:0010705 meiotic DNA double-strand break processing involved in reciprocal meiotic recombination IBA
 biological_processGO:0031297 replication fork processing ISO
 biological_processGO:0032508 DNA duplex unwinding ISO
 biological_processGO:0035690 cellular response to drug IGI
 biological_processGO:0043066 negative regulation of apoptotic process IBA
 biological_processGO:0044237 cellular metabolic process IEA
 biological_processGO:0044806 G-quadruplex DNA unwinding ISO
 biological_processGO:0045003 double-strand break repair via synthesis-dependent strand annealing IBA
 biological_processGO:0045893 positive regulation of transcription, DNA-templated ISO
 biological_processGO:0045910 negative regulation of DNA recombination ISO
 biological_processGO:0045950 negative regulation of mitotic recombination IMP
 biological_processGO:0046632 alpha-beta T cell differentiation IMP
 biological_processGO:0046641 positive regulation of alpha-beta T cell proliferation IMP
 biological_processGO:0051098 regulation of binding IDA
 biological_processGO:0051259 protein complex oligomerization ISO
 biological_processGO:0051260 protein homooligomerization ISO
 biological_processGO:0051276 chromosome organization IMP
 biological_processGO:0051307 meiotic chromosome separation IBA
 biological_processGO:0051782 negative regulation of cell division ISO
 biological_processGO:0061820 telomeric D-loop disassembly ISO
 biological_processGO:0070244 negative regulation of thymocyte apoptotic process IMP
 biological_processGO:0071139 resolution of recombination intermediates IBA
 biological_processGO:0071479 cellular response to ionizing radiation ISO
 biological_processGO:0072711 cellular response to hydroxyurea ISO
 biological_processGO:0072757 cellular response to camptothecin ISO
 biological_processGO:0090329 regulation of DNA-dependent DNA replication ISO
 biological_processGO:1901291 negative regulation of double-strand break repair via single-strand annealing IBA
 biological_processGO:1905168 positive regulation of double-strand break repair via homologous recombination IGI
 biological_processGO:1990414 replication-born double-strand break repair via sister chromatid exchange IMP
 cellular_componentGO:0000228 nuclear chromosome ISO
 cellular_componentGO:0000781 chromosome, telomeric region ISO
 cellular_componentGO:0000800 lateral element ISO
 cellular_componentGO:0001673 male germ cell nucleus IDA
 cellular_componentGO:0005622 intracellular IEA
 cellular_componentGO:0005634 nucleus ISO
 cellular_componentGO:0005657 replication fork IMP
 cellular_componentGO:0005694 chromosome IBA
 cellular_componentGO:0005730 nucleolus ISO
 cellular_componentGO:0005737 cytoplasm IDA
 cellular_componentGO:0005829 cytosol ISO
 cellular_componentGO:0016363 nuclear matrix ISO
 cellular_componentGO:0016605 PML body ISO
 cellular_componentGO:0045120 pronucleus IDA
 molecular_functionGO:0000166 nucleotide binding IEA
 molecular_functionGO:0000400 four-way junction DNA binding ISO
 molecular_functionGO:0000403 Y-form DNA binding ISO
 molecular_functionGO:0000405 bubble DNA binding ISO
 molecular_functionGO:0002039 p53 binding ISO
 molecular_functionGO:0003676 nucleic acid binding IEA
 molecular_functionGO:0003677 DNA binding ISO
 molecular_functionGO:0003678 DNA helicase activity ISO
 molecular_functionGO:0003697 single-stranded DNA binding ISO
 molecular_functionGO:0003824 catalytic activity IEA
 molecular_functionGO:0004003 ATP-dependent DNA helicase activity ISO
 molecular_functionGO:0004386 helicase activity ISO
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0005524 ATP binding ISO
 molecular_functionGO:0008026 ATP-dependent helicase activity ISO
 molecular_functionGO:0008094 DNA-dependent ATPase activity ISO
 molecular_functionGO:0008270 zinc ion binding ISO
 molecular_functionGO:0009378 four-way junction helicase activity ISO
 molecular_functionGO:0016787 hydrolase activity IEA
 molecular_functionGO:0016818 hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides IEA
 molecular_functionGO:0016887 ATPase activity ISO
 molecular_functionGO:0036310 annealing helicase activity ISO
 molecular_functionGO:0042803 protein homodimerization activity ISO
 molecular_functionGO:0043140 ATP-dependent 3"-5" DNA helicase activity IDA
 molecular_functionGO:0046872 metal ion binding IEA
 molecular_functionGO:0051880 G-quadruplex DNA binding ISO
 molecular_functionGO:0061749 forked DNA-dependent helicase activity ISO
 molecular_functionGO:0061821 telomeric D-loop binding ISO
 molecular_functionGO:1905773 8-hydroxy-2"-deoxyguanosine DNA binding ISO


Pathways (from Reactome)
Pathway description
No match


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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