12168


Mus musculus (NCBI)

Features
Gene ID: 12168
  
Biological name :
  
Synonyms : 2610024H22Rik|AL117858|AW546137|BB189135|BMP-2|BMPR-2|BMPR-II|BMPRII|BRK-3|Gm20272 / Bmpr2 / bone morphogenetic protein receptor, type II (serine/threonine kinase)
  
Possible biological names infered from orthology :
  
Species: Mus musculus (NCBI)
  
Chr. number:
Strand:
Band:
Gene start:
Gene end:
  
Corresponding Affymetrix probe sets: 1419616_at (Mouse Genome 430 2.0 Array)   1434310_at (Mouse Genome 430 2.0 Array)   1441652_at (Mouse Genome 430 2.0 Array)   
  
Cross references: RefSeq - 6680804
RefSeq - XP_006495696.1
RefSeq - NC_000067.6
RefSeq - 568905656
RefSeq - NP_031587.1
RefSeq - NM_007561.4
RefSeq - XM_006495633.1
  
See co-cited genes in PubMed
Warning: Please see the Ensembl gene model ENSMUSG00000067336 to get all the annotations available for this gene.


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0001568 blood vessel development IBA
 biological_processGO:0001707 mesoderm formation IMP
 biological_processGO:0001893 maternal placenta development IMP
 biological_processGO:0001934 positive regulation of protein phosphorylation ISO
 biological_processGO:0001935 endothelial cell proliferation ISO
 biological_processGO:0001938 positive regulation of endothelial cell proliferation ISO
 biological_processGO:0001944 vasculature development IBA
 biological_processGO:0001946 lymphangiogenesis IMP
 biological_processGO:0001974 blood vessel remodeling IMP
 biological_processGO:0002063 chondrocyte development ISO
 biological_processGO:0003085 negative regulation of systemic arterial blood pressure ISO
 biological_processGO:0003148 outflow tract septum morphogenesis IMP
 biological_processGO:0003151 outflow tract morphogenesis IMP
 biological_processGO:0003181 atrioventricular valve morphogenesis IMP
 biological_processGO:0003183 mitral valve morphogenesis IMP
 biological_processGO:0003186 tricuspid valve morphogenesis IMP
 biological_processGO:0003197 endocardial cushion development IMP
 biological_processGO:0003252 negative regulation of cell proliferation involved in heart valve morphogenesis IMP
 biological_processGO:0006366 transcription by RNA polymerase II ISO
 biological_processGO:0007178 transmembrane receptor protein serine/threonine kinase signaling pathway ISO
 biological_processGO:0007179 transforming growth factor beta receptor signaling pathway IBA
 biological_processGO:0007389 pattern specification process IBA
 biological_processGO:0009952 anterior/posterior pattern specification IMP
 biological_processGO:0010595 positive regulation of endothelial cell migration ISO
 biological_processGO:0010634 positive regulation of epithelial cell migration ISO
 biological_processGO:0010862 positive regulation of pathway-restricted SMAD protein phosphorylation ISO
 biological_processGO:0014916 regulation of lung blood pressure ISO
 biological_processGO:0016310 phosphorylation IEA
 biological_processGO:0030308 negative regulation of cell growth ISO
 biological_processGO:0030501 positive regulation of bone mineralization ISO
 biological_processGO:0030509 BMP signaling pathway ISO
 biological_processGO:0030513 positive regulation of BMP signaling pathway ISO
 biological_processGO:0042127 regulation of cell proliferation ISO
 biological_processGO:0045669 positive regulation of osteoblast differentiation ISO
 biological_processGO:0045778 positive regulation of ossification IMP
 biological_processGO:0045906 negative regulation of vasoconstriction IMP
 biological_processGO:0045944 positive regulation of transcription by RNA polymerase II ISO
 biological_processGO:0048010 vascular endothelial growth factor receptor signaling pathway IMP
 biological_processGO:0048286 lung alveolus development IMP
 biological_processGO:0048738 cardiac muscle tissue development IMP
 biological_processGO:0048842 positive regulation of axon extension involved in axon guidance IMP
 biological_processGO:0060173 limb development IGI
 biological_processGO:0060412 ventricular septum morphogenesis IMP
 biological_processGO:0060413 atrial septum morphogenesis IMP
 biological_processGO:0060836 lymphatic endothelial cell differentiation IMP
 biological_processGO:0060840 artery development IMP
 biological_processGO:0060841 venous blood vessel development IMP
 biological_processGO:0061298 retina vasculature development in camera-type eye IMP
 biological_processGO:0061626 pharyngeal arch artery morphogenesis IMP
 biological_processGO:0071773 cellular response to BMP stimulus ISO
 biological_processGO:0072577 endothelial cell apoptotic process ISO
 biological_processGO:1902731 negative regulation of chondrocyte proliferation ISO
 biological_processGO:1905314 semi-lunar valve development IMP
 biological_processGO:2000279 negative regulation of DNA biosynthetic process ISO
 cellular_componentGO:0005654 nucleoplasm ISO
 cellular_componentGO:0005737 cytoplasm ISO
 cellular_componentGO:0005886 plasma membrane ISO
 cellular_componentGO:0005887 integral component of plasma membrane ISO
 cellular_componentGO:0005901 caveola ISO
 cellular_componentGO:0005913 cell-cell adherens junction ISO
 cellular_componentGO:0009925 basal plasma membrane ISO
 cellular_componentGO:0009986 cell surface IDA
 cellular_componentGO:0014069 postsynaptic density IDA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 cellular_componentGO:0016324 apical plasma membrane ISO
 cellular_componentGO:0030425 dendrite ISO
 cellular_componentGO:0043025 neuronal cell body ISO
 cellular_componentGO:0043235 receptor complex IBA
 molecular_functionGO:0000166 nucleotide binding IEA
 molecular_functionGO:0004672 protein kinase activity IEA
 molecular_functionGO:0004674 protein serine/threonine kinase activity IEA
 molecular_functionGO:0005024 transforming growth factor beta-activated receptor activity IBA
 molecular_functionGO:0005026 transforming growth factor beta receptor activity, type II IBA
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0005524 ATP binding IEA
 molecular_functionGO:0016301 kinase activity IEA
 molecular_functionGO:0016740 transferase activity IEA
 molecular_functionGO:0019838 growth factor binding ISO
 molecular_functionGO:0036122 BMP binding ISO
 molecular_functionGO:0046332 SMAD binding IBA
 molecular_functionGO:0046872 metal ion binding IEA
 molecular_functionGO:0098821 BMP receptor activity IMP


Pathways (from Reactome)
Pathway description
No match


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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