12189


Mus musculus (NCBI)

Features
Gene ID: 12189
  
Biological name :
  
Synonyms : Brca1 / breast cancer 1, early onset
  
Possible biological names infered from orthology :
  
Species: Mus musculus (NCBI)
  
Chr. number:
Strand:
Band:
Gene start:
Gene end:
  
Corresponding Affymetrix probe sets: 1424629_at (Mouse Genome 430 2.0 Array)   1424630_a_at (Mouse Genome 430 2.0 Array)   1427698_at (Mouse Genome 430 2.0 Array)   1451417_at (Mouse Genome 430 2.0 Array)   
  
Cross references: RefSeq - XP_017169722.1
RefSeq - 161016835
RefSeq - 568971322
RefSeq - 568971330
RefSeq - NC_000077.6
RefSeq - NP_033894.3
RefSeq - XP_006532127.1
RefSeq - XP_006532131.1
RefSeq - 1039735465
RefSeq - NM_009764.3
RefSeq - XM_017314233.1
RefSeq - XM_006532064.3
RefSeq - XM_006532068.2
  
See co-cited genes in PubMed
Warning: Please see the Ensembl gene model ENSMUSG00000017146 to get all the annotations available for this gene.


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0000724 double-strand break repair via homologous recombination ISO
 biological_processGO:0006281 DNA repair IEA
 biological_processGO:0006301 postreplication repair ISO
 biological_processGO:0006302 double-strand break repair ISO
 biological_processGO:0006310 DNA recombination IEA
 biological_processGO:0006349 regulation of gene expression by genetic imprinting IMP
 biological_processGO:0006351 transcription, DNA-templated IEA
 biological_processGO:0006355 regulation of transcription, DNA-templated IEA
 biological_processGO:0006357 regulation of transcription by RNA polymerase II ISO
 biological_processGO:0006629 lipid metabolic process IEA
 biological_processGO:0006631 fatty acid metabolic process IEA
 biological_processGO:0006633 fatty acid biosynthetic process IEA
 biological_processGO:0006974 cellular response to DNA damage stimulus IMP
 biological_processGO:0007049 cell cycle IEA
 biological_processGO:0007059 chromosome segregation ISO
 biological_processGO:0007098 centrosome cycle IGI
 biological_processGO:0008630 intrinsic apoptotic signaling pathway in response to DNA damage ISO
 biological_processGO:0009048 dosage compensation by inactivation of X chromosome IDA
 biological_processGO:0010212 response to ionizing radiation ISO
 biological_processGO:0010575 positive regulation of vascular endothelial growth factor production ISO
 biological_processGO:0010628 positive regulation of gene expression ISO
 biological_processGO:0016567 protein ubiquitination ISO
 biological_processGO:0031398 positive regulation of protein ubiquitination ISO
 biological_processGO:0033147 negative regulation of intracellular estrogen receptor signaling pathway ISO
 biological_processGO:0033160 positive regulation of protein import into nucleus, translocation ISO
 biological_processGO:0035066 positive regulation of histone acetylation ISO
 biological_processGO:0035067 negative regulation of histone acetylation IMP
 biological_processGO:0043009 chordate embryonic development IMP
 biological_processGO:0043627 response to estrogen ISO
 biological_processGO:0044030 regulation of DNA methylation IMP
 biological_processGO:0044818 mitotic G2/M transition checkpoint IMP
 biological_processGO:0045717 negative regulation of fatty acid biosynthetic process ISO
 biological_processGO:0045739 positive regulation of DNA repair ISO
 biological_processGO:0045766 positive regulation of angiogenesis ISO
 biological_processGO:0045892 negative regulation of transcription, DNA-templated ISO
 biological_processGO:0045893 positive regulation of transcription, DNA-templated ISO
 biological_processGO:0045944 positive regulation of transcription by RNA polymerase II ISO
 biological_processGO:0051298 centrosome duplication TAS
 biological_processGO:0051571 positive regulation of histone H3-K4 methylation ISO
 biological_processGO:0051572 negative regulation of histone H3-K4 methylation IMP
 biological_processGO:0051573 negative regulation of histone H3-K9 methylation ISO
 biological_processGO:0051574 positive regulation of histone H3-K9 methylation IMP
 biological_processGO:0051865 protein autoubiquitination ISO
 biological_processGO:0070512 positive regulation of histone H4-K20 methylation ISO
 biological_processGO:0071158 positive regulation of cell cycle arrest ISO
 biological_processGO:0071356 cellular response to tumor necrosis factor ISO
 biological_processGO:0071681 cellular response to indole-3-methanol ISO
 biological_processGO:0072425 signal transduction involved in G2 DNA damage checkpoint ISO
 biological_processGO:0085020 protein K6-linked ubiquitination ISO
 biological_processGO:1902042 negative regulation of extrinsic apoptotic signaling pathway via death domain receptors ISO
 biological_processGO:2000378 negative regulation of reactive oxygen species metabolic process ISO
 biological_processGO:2000617 positive regulation of histone H3-K9 acetylation ISO
 biological_processGO:2000620 positive regulation of histone H4-K16 acetylation ISO
 cellular_componentGO:0000793 condensed chromosome IDA
 cellular_componentGO:0000794 condensed nuclear chromosome IDA
 cellular_componentGO:0000800 lateral element ISO
 cellular_componentGO:0005634 nucleus ISO
 cellular_componentGO:0005694 chromosome IDA
 cellular_componentGO:0005737 cytoplasm ISO
 cellular_componentGO:0005759 mitochondrial matrix ISO
 cellular_componentGO:0005813 centrosome TAS
 cellular_componentGO:0005886 plasma membrane ISO
 cellular_componentGO:0031436 BRCA1-BARD1 complex ISO
 cellular_componentGO:0032991 protein-containing complex ISO
 cellular_componentGO:0070531 BRCA1-A complex ISO
 cellular_componentGO:1990904 ribonucleoprotein complex ISO
 molecular_functionGO:0003677 DNA binding IEA
 molecular_functionGO:0003682 chromatin binding ISO
 molecular_functionGO:0003684 damaged DNA binding IDA
 molecular_functionGO:0003713 transcription coactivator activity ISO
 molecular_functionGO:0003723 RNA binding ISO
 molecular_functionGO:0004842 ubiquitin-protein transferase activity ISO
 molecular_functionGO:0008270 zinc ion binding IEA
 molecular_functionGO:0016740 transferase activity IEA
 molecular_functionGO:0019899 enzyme binding ISO
 molecular_functionGO:0031625 ubiquitin protein ligase binding ISO
 molecular_functionGO:0044212 transcription regulatory region DNA binding ISO
 molecular_functionGO:0046872 metal ion binding IEA
 molecular_functionGO:0070063 RNA polymerase binding ISO


Pathways (from Reactome)
Pathway description
No match


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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