12229


Mus musculus (NCBI)

Features
Gene ID: 12229
  
Biological name :
  
Synonyms : AI528679|xid / Bruton agammaglobulinemia tyrosine kinase / Btk
  
Possible biological names infered from orthology :
  
Species: Mus musculus (NCBI)
  
Chr. number:
Strand:
Band:
Gene start:
Gene end:
  
Corresponding Affymetrix probe sets: 1422755_at (Mouse Genome 430 2.0 Array)   
  
Cross references: RefSeq - XP_006528548.1
RefSeq - 569011232
RefSeq - 569011234
RefSeq - 569011236
RefSeq - NC_000086.7
RefSeq - NP_038510.2
RefSeq - XP_006528546.1
RefSeq - XP_006528547.1
RefSeq - 161016839
RefSeq - NM_013482.2
RefSeq - XM_006528485.3
RefSeq - XM_006528483.3
RefSeq - XM_006528484.3
  
See co-cited genes in PubMed
Warning: Please see the Ensembl gene model ENSMUSG00000031264 to get all the annotations available for this gene.


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0001805 positive regulation of type III hypersensitivity ISO
 biological_processGO:0001812 positive regulation of type I hypersensitivity ISO
 biological_processGO:0001818 negative regulation of cytokine production IMP
 biological_processGO:0002250 adaptive immune response IEA
 biological_processGO:0002344 B cell affinity maturation IMP
 biological_processGO:0002376 immune system process IEA
 biological_processGO:0002553 histamine secretion by mast cell ISO
 biological_processGO:0006351 transcription, DNA-templated IEA
 biological_processGO:0006355 regulation of transcription, DNA-templated IEA
 biological_processGO:0006468 protein phosphorylation IDA
 biological_processGO:0006915 apoptotic process IEA
 biological_processGO:0007169 transmembrane receptor protein tyrosine kinase signaling pathway IBA
 biological_processGO:0007249 I-kappaB kinase/NF-kappaB signaling IMP
 biological_processGO:0010033 response to organic substance ISO
 biological_processGO:0016310 phosphorylation IEA
 biological_processGO:0018108 peptidyl-tyrosine phosphorylation ISO
 biological_processGO:0030154 cell differentiation IBA
 biological_processGO:0030889 negative regulation of B cell proliferation IMP
 biological_processGO:0034614 cellular response to reactive oxygen species ISO
 biological_processGO:0035556 intracellular signal transduction IEA
 biological_processGO:0038083 peptidyl-tyrosine autophosphorylation IBA
 biological_processGO:0042127 regulation of cell proliferation IBA
 biological_processGO:0045087 innate immune response IBA
 biological_processGO:0046777 protein autophosphorylation ISO
 biological_processGO:0048469 cell maturation IMP
 biological_processGO:0050852 T cell receptor signaling pathway IBA
 biological_processGO:0050853 B cell receptor signaling pathway IBA
 biological_processGO:0071226 cellular response to molecule of fungal origin ISO
 biological_processGO:0098761 cellular response to interleukin-7 IMP
 cellular_componentGO:0005634 nucleus IDA
 cellular_componentGO:0005737 cytoplasm IDA
 cellular_componentGO:0005829 cytosol ISO
 cellular_componentGO:0005886 plasma membrane ISO
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0031234 extrinsic component of cytoplasmic side of plasma membrane IBA
 cellular_componentGO:0031410 cytoplasmic vesicle IDA
 cellular_componentGO:0045121 membrane raft ISO
 cellular_componentGO:0048471 perinuclear region of cytoplasm ISO
 molecular_functionGO:0000166 nucleotide binding IEA
 molecular_functionGO:0004672 protein kinase activity IEA
 molecular_functionGO:0004713 protein tyrosine kinase activity ISO
 molecular_functionGO:0004715 non-membrane spanning protein tyrosine kinase activity IBA
 molecular_functionGO:0005102 signaling receptor binding IBA
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0005524 ATP binding IEA
 molecular_functionGO:0005547 phosphatidylinositol-3,4,5-trisphosphate binding ISO
 molecular_functionGO:0008289 lipid binding IEA
 molecular_functionGO:0016301 kinase activity IEA
 molecular_functionGO:0016740 transferase activity IEA
 molecular_functionGO:0042802 identical protein binding ISO
 molecular_functionGO:0046872 metal ion binding IEA


Pathways (from Reactome)
Pathway description
No match


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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