12305


Mus musculus (NCBI)
kinaseactivityregulationproteinreceptortyrosinemembranebindingcelldevelopmentphosphorylationtransmembranesignalingplasmacell-matrixadhesionpathwaysmoothmusclepeptidyl-tyrosineautophosphorylationmammaryglanderkintegralcomponentcollagengrowthmulticellularorganism

Features
Gene ID: 12305
  
Biological name :
  
Synonyms : 6030432F18|AI323681|CD167a|Cak|Nep|PTK3A / Ddr1 / discoidin domain receptor family, member 1
  
Possible biological names infered from orthology :
  
Species: Mus musculus (NCBI)
  
Chr. number:
Strand:
Band:
Gene start:
Gene end:
  
Corresponding Affymetrix probe sets: 1415797_at (Mouse Genome 430 2.0 Array)   1415798_at (Mouse Genome 430 2.0 Array)   1435820_x_at (Mouse Genome 430 2.0 Array)   1437619_x_at (Mouse Genome 430 2.0 Array)   1438367_x_at (Mouse Genome 430 2.0 Array)   1439382_x_at (Mouse Genome 430 2.0 Array)   1456226_x_at (Mouse Genome 430 2.0 Array)   1459990_at (Mouse Genome 430 2.0 Array)   
  
Cross references: RefSeq - 119709814
RefSeq - 311771514
RefSeq - 311771518
RefSeq - 568998750
RefSeq - 568998752
RefSeq - 568998754
RefSeq - 568998756
RefSeq - 568998758
RefSeq - 568998760
RefSeq - 6680828
RefSeq - 755555852
RefSeq - NC_000083.6
RefSeq - NP_001185762.1
RefSeq - NP_031610.1
RefSeq - NP_766550.1
RefSeq - NT_187004.1
RefSeq - NT_187027.1
RefSeq - XP_006523596.1
RefSeq - XP_006523597.1
RefSeq - XP_006523598.1
RefSeq - XP_006523599.1
RefSeq - XP_006523600.1
RefSeq - XP_006523601.1
RefSeq - XP_011244561.1
RefSeq - NP_001185760.1
RefSeq - NM_001198831.1
RefSeq - NM_001198833.1
RefSeq - NM_007584.3
RefSeq - NM_172962.1
RefSeq - XM_006523535.3
RefSeq - XM_006523536.3
RefSeq - XM_006523537.1
RefSeq - XM_006523538.3
RefSeq - XM_011246259.1
RefSeq - XR_001782030.1
RefSeq - XM_006523533.1
RefSeq - XM_006523534.1
  
See co-cited genes in PubMed
Warning: Please see the Ensembl gene model ENSMUSG00000003534 to get all the annotations available for this gene.


Gene Ontology (GO)
cellular component organizationcell growthcell adhesionnitrogen compound metabolic processcellular metabolic processprimary metabolic processorganic substance metabolic processcell communicationcellular response to stimulusanatomical structure developmentmulti-multicellular organism processestablishment of localizationregulation of biological qualitylocalization of cellmovement of cell or subcellular componentcellular developmental processregulation of molecular functioncell deathresponse to stressdevelopmental growthcellular component organizationcell growthcell adhesionnitrogen compound metabolic processcellular metabolic processprimary metabolic processorganic substance metabolic processcell communicationcellular response to stimulusanatomical structure developmentmulti-multicellular organism processestablishment of localizationregulation of biological qualitylocalization of cellmovement of cell or subcellular componentcellular developmental processregulation of molecular functioncell deathresponse to stressdevelopmental growthcellular component organizationcell growthcell adhesionnitrogen compound metabolic processcellular metabolic processprimary metabolic processorganic substance metabolic processcell communicationcellular response to stimulusanatomical structure developmentmulti-multicellular organism processestablishment of localizationregulation of biological qualitylocalization of cellmovement of cell or subcellular componentcellular developmental processregulation of molecular functioncell deathresponse to stressdevelopmental growthcellular component organizationcell growthcell adhesionnitrogen compound metabolic processcellular metabolic processprimary metabolic processorganic substance metabolic processcell communicationcellular response to stimulusanatomical structure developmentmulti-multicellular organism processestablishment of localizationregulation of biological qualitylocalization of cellmovement of cell or subcellular componentcellular developmental processregulation of molecular functioncell deathresponse to stressdevelopmental growthcellular component organizationcell growthcell adhesionnitrogen compound metabolic processcellular metabolic processprimary metabolic processorganic substance metabolic processcell communicationcellular response to stimulusanatomical structure developmentmulti-multicellular organism processestablishment of localizationregulation of biological qualitylocalization of cellmovement of cell or subcellular componentcellular developmental processregulation of molecular functioncell deathresponse to stressdevelopmental growthcellular component organizationcell growthcell adhesionnitrogen compound metabolic processcellular metabolic processprimary metabolic processorganic substance metabolic processcell communicationcellular response to stimulusanatomical structure developmentmulti-multicellular organism processestablishment of localizationregulation of biological qualitylocalization of cellmovement of cell or subcellular componentcellular developmental processregulation of molecular functioncell deathresponse to stressdevelopmental growthcellular component organizationcell growthcell adhesionnitrogen compound metabolic processcellular metabolic processprimary metabolic processorganic substance metabolic processcell communicationcellular response to stimulusanatomical structure developmentmulti-multicellular organism processestablishment of localizationregulation of biological qualitylocalization of cellmovement of cell or subcellular componentcellular developmental processregulation of molecular functioncell deathresponse to stressdevelopmental growthcellular component organizationcell growthcell adhesionnitrogen compound metabolic processcellular metabolic processprimary metabolic processorganic substance metabolic processcell communicationcellular response to stimulusanatomical structure developmentmulti-multicellular organism processestablishment of localizationregulation of biological qualitylocalization of cellmovement of cell or subcellular componentcellular developmental processregulation of molecular functioncell deathresponse to stressdevelopmental growthcellular component organizationcell growthcell adhesionnitrogen compound metabolic processcellular metabolic processprimary metabolic processorganic substance metabolic processcell communicationcellular response to stimulusanatomical structure developmentmulti-multicellular organism processestablishment of localizationregulation of biological qualitylocalization of cellmovement of cell or subcellular componentcellular developmental processregulation of molecular functioncell deathresponse to stressdevelopmental growthcellular component organizationcell growthcell adhesionnitrogen compound metabolic processcellular metabolic processprimary metabolic processorganic substance metabolic processcell communicationcellular response to stimulusanatomical structure developmentmulti-multicellular organism processestablishment of localizationregulation of biological qualitylocalization of cellmovement of cell or subcellular componentcellular developmental processregulation of molecular functioncell deathresponse to stressdevelopmental growthcellulacellular component organizationcell grcell growthcell adcell adhesionnitrogenitrogen compound metabolic processcellulacellular metabolic processprimaryprimary metabolic processorganicorganic substance metabolic processcell cocell communicationcellulacellular response to stimulusanatomianatomical structure developmentmulti-mmulti-multicellular organism processestabliestablishment of localizationregulatregulation of biological qualitylocalizlocalization of cellmovemenmovement of cell or subcellular componentcellulacellular developmental processregulatregulation of molecular functioncell decell deathresponsresponse to stressdevelopdevelopmental growth
organic cyclic compound bindingheterocyclic compound bindingsmall molecule bindingcatalytic activity, acting on a proteintransferase activitysignaling receptor activityprotein-containing complex bindingion bindingcarbohydrate derivative bindingdrug bindingprotein bindingorganic cyclic compound bindingheterocyclic compound bindingsmall molecule bindingcatalytic activity, acting on a proteintransferase activitysignaling receptor activityprotein-containing complex bindingion bindingcarbohydrate derivative bindingdrug bindingprotein bindingorganic cyclic compound bindingheterocyclic compound bindingsmall molecule bindingcatalytic activity, acting on a proteintransferase activitysignaling receptor activityprotein-containing complex bindingion bindingcarbohydrate derivative bindingdrug bindingprotein bindingorganic cyclic compound bindingheterocyclic compound bindingsmall molecule bindingcatalytic activity, acting on a proteintransferase activitysignaling receptor activityprotein-containing complex bindingion bindingcarbohydrate derivative bindingdrug bindingprotein bindingorganic cyclic compound bindingheterocyclic compound bindingsmall molecule bindingcatalytic activity, acting on a proteintransferase activitysignaling receptor activityprotein-containing complex bindingion bindingcarbohydrate derivative bindingdrug bindingprotein bindingorganic cyclic compound bindingheterocyclic compound bindingsmall molecule bindingcatalytic activity, acting on a proteintransferase activitysignaling receptor activityprotein-containing complex bindingion bindingcarbohydrate derivative bindingdrug bindingprotein bindingorganic cyclic compound bindingheterocyclic compound bindingsmall molecule bindingcatalytic activity, acting on a proteintransferase activitysignaling receptor activityprotein-containing complex bindingion bindingcarbohydrate derivative bindingdrug bindingprotein bindingorganic cyclic compound bindingheterocyclic compound bindingsmall molecule bindingcatalytic activity, acting on a proteintransferase activitysignaling receptor activityprotein-containing complex bindingion bindingcarbohydrate derivative bindingdrug bindingprotein bindingorganic cyclic compound bindingheterocyclic compound bindingsmall molecule bindingcatalytic activity, acting on a proteintransferase activitysignaling receptor activityprotein-containing complex bindingion bindingcarbohydrate derivative bindingdrug bindingprotein bindingorganic cyclic compound bindingheterocyclic compound bindingsmall molecule bindingcatalytic activity, acting on a proteintransferase activitysignaling receptor activityprotein-containing complex bindingion bindingcarbohydrate derivative bindingdrug bindingprotein bindingorganic cyclorganic cyclic compound bindingheterocyclicheterocyclic compound bindingsmall molecusmall molecule bindingcatalytic accatalytic activity, acting on a proteintransferase transferase activitysignaling resignaling receptor activityprotein-contprotein-containing complex bindingion bindingion bindingcarbohydratecarbohydrate derivative bindingdrug bindingdrug bindingprotein bindprotein binding
cellmembraneprotein-containing complexcellmembraneprotein-containing complexcellmembraneprotein-containing complexcellmembraneprotein-containing complexcellmembraneprotein-containing complexcellmembraneprotein-containing complexcellmembraneprotein-containing complexcellmembraneprotein-containing complexcellmembraneprotein-containing complexcellmembraneprotein-containing complexcellcellmembranemembraneprotein-containing complexprotein-containing complex
TypeGO IDTermEv.Code
 biological_processGO:0001558 regulation of cell growth IMP
 biological_processGO:0001952 regulation of cell-matrix adhesion IMP
 biological_processGO:0006468 protein phosphorylation IEA
 biological_processGO:0007169 transmembrane receptor protein tyrosine kinase signaling pathway IEA
 biological_processGO:0007275 multicellular organism development IBA
 biological_processGO:0007565 female pregnancy IEA
 biological_processGO:0007566 embryo implantation IMP
 biological_processGO:0007595 lactation IEA
 biological_processGO:0008285 negative regulation of cell proliferation IMP
 biological_processGO:0009968 negative regulation of signal transduction IBA
 biological_processGO:0010715 regulation of extracellular matrix disassembly ISO
 biological_processGO:0014909 smooth muscle cell migration ISO
 biological_processGO:0016310 phosphorylation IEA
 biological_processGO:0018108 peptidyl-tyrosine phosphorylation IDA
 biological_processGO:0030154 cell differentiation IBA
 biological_processGO:0033674 positive regulation of kinase activity IBA
 biological_processGO:0038063 collagen-activated tyrosine kinase receptor signaling pathway ISO
 biological_processGO:0038083 peptidyl-tyrosine autophosphorylation ISO
 biological_processGO:0043066 negative regulation of apoptotic process IBA
 biological_processGO:0043583 ear development IMP
 biological_processGO:0044319 wound healing, spreading of cells ISO
 biological_processGO:0046777 protein autophosphorylation ISO
 biological_processGO:0060444 branching involved in mammary gland duct morphogenesis IMP
 biological_processGO:0060749 mammary gland alveolus development IMP
 biological_processGO:0061302 smooth muscle cell-matrix adhesion ISO
 biological_processGO:0061564 axon development IMP
 biological_processGO:0070374 positive regulation of ERK1 and ERK2 cascade IBA
 biological_processGO:1990138 neuron projection extension IMP
 cellular_componentGO:0005737 cytoplasm ISO
 cellular_componentGO:0005886 plasma membrane IDA
 cellular_componentGO:0005887 integral component of plasma membrane IEA
 cellular_componentGO:0005903 brush border ISO
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 cellular_componentGO:0016323 basolateral plasma membrane ISO
 cellular_componentGO:0043235 receptor complex ISO
 molecular_functionGO:0000166 nucleotide binding IEA
 molecular_functionGO:0004672 protein kinase activity IEA
 molecular_functionGO:0004709 MAP kinase kinase kinase activity IBA
 molecular_functionGO:0004713 protein tyrosine kinase activity IEA
 molecular_functionGO:0004714 transmembrane receptor protein tyrosine kinase activity IEA
 molecular_functionGO:0004888 transmembrane signaling receptor activity IBA
 molecular_functionGO:0005518 collagen binding ISO
 molecular_functionGO:0005524 ATP binding IEA
 molecular_functionGO:0016301 kinase activity IEA
 molecular_functionGO:0016740 transferase activity IEA
 molecular_functionGO:0031434 mitogen-activated protein kinase kinase binding IBA
 molecular_functionGO:0038062 protein tyrosine kinase collagen receptor activity ISO
 molecular_functionGO:0046872 metal ion binding IEA


Pathways (from Reactome)
Pathway description
No match


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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