12362


Mus musculus (NCBI)

Features
Gene ID: 12362
  
Biological name :
  
Synonyms : Casp1 / caspase 1 / ICE|Il1bc
  
Possible biological names infered from orthology :
  
Species: Mus musculus (NCBI)
  
Chr. number:
Strand:
Band:
Gene start:
Gene end:
  
Corresponding Affymetrix probe sets: 1449265_at (Mouse Genome 430 2.0 Array)   
  
Cross references: RefSeq - 86198305
RefSeq - NC_000075.6
RefSeq - NP_033937.2
RefSeq - NM_009807.2
  
See co-cited genes in PubMed
Warning: Please see the Ensembl gene model ENSMUSG00000025888 to get all the annotations available for this gene.


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0001666 response to hypoxia ISO
 biological_processGO:0001774 microglial cell activation ISO
 biological_processGO:0006508 proteolysis ISO
 biological_processGO:0006915 apoptotic process IEA
 biological_processGO:0006919 activation of cysteine-type endopeptidase activity involved in apoptotic process IBA
 biological_processGO:0007520 myoblast fusion ISO
 biological_processGO:0007613 memory ISO
 biological_processGO:0009617 response to bacterium IMP
 biological_processGO:0010506 regulation of autophagy IMP
 biological_processGO:0014070 response to organic cyclic compound ISO
 biological_processGO:0016485 protein processing IMP
 biological_processGO:0016540 protein autoprocessing ISO
 biological_processGO:0032496 response to lipopolysaccharide ISO
 biological_processGO:0032611 interleukin-1 beta production IGI
 biological_processGO:0033198 response to ATP IMP
 biological_processGO:0042493 response to drug ISO
 biological_processGO:0042981 regulation of apoptotic process IEA
 biological_processGO:0043065 positive regulation of apoptotic process ISO
 biological_processGO:0043123 positive regulation of I-kappaB kinase/NF-kappaB signaling ISO
 biological_processGO:0043280 positive regulation of cysteine-type endopeptidase activity involved in apoptotic process ISO
 biological_processGO:0046010 positive regulation of circadian sleep/wake cycle, non-REM sleep ISO
 biological_processGO:0050715 positive regulation of cytokine secretion ISO
 biological_processGO:0050717 positive regulation of interleukin-1 alpha secretion IMP
 biological_processGO:0050718 positive regulation of interleukin-1 beta secretion ISO
 biological_processGO:0050727 regulation of inflammatory response IMP
 biological_processGO:0051882 mitochondrial depolarization IMP
 biological_processGO:0060081 membrane hyperpolarization IMP
 biological_processGO:0070269 pyroptosis IMP
 biological_processGO:0071222 cellular response to lipopolysaccharide ISO
 biological_processGO:0071310 cellular response to organic substance ISO
 biological_processGO:0071346 cellular response to interferon-gamma ISO
 biological_processGO:0097194 execution phase of apoptosis IBA
 biological_processGO:0097300 programmed necrotic cell death IDA
 biological_processGO:1901998 toxin transport IMP
 biological_processGO:1903265 positive regulation of tumor necrosis factor-mediated signaling pathway ISO
 cellular_componentGO:0005576 extracellular region IDA
 cellular_componentGO:0005634 nucleus ISO
 cellular_componentGO:0005737 cytoplasm TAS
 cellular_componentGO:0032991 protein-containing complex ISO
 cellular_componentGO:0043005 neuron projection ISO
 cellular_componentGO:0072557 IPAF inflammasome complex IDA
 cellular_componentGO:0072558 NLRP1 inflammasome complex ISO
 cellular_componentGO:0072559 NLRP3 inflammasome complex ISO
 cellular_componentGO:0097169 AIM2 inflammasome complex ISO
 cellular_componentGO:0097179 protease inhibitor complex ISO
 molecular_functionGO:0004175 endopeptidase activity ISO
 molecular_functionGO:0004197 cysteine-type endopeptidase activity ISO
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0008233 peptidase activity IDA
 molecular_functionGO:0008234 cysteine-type peptidase activity IEA
 molecular_functionGO:0016787 hydrolase activity IEA
 molecular_functionGO:0019900 kinase binding ISO
 molecular_functionGO:0042802 identical protein binding ISO
 molecular_functionGO:0050700 CARD domain binding ISO
 molecular_functionGO:0097110 scaffold protein binding ISO
 molecular_functionGO:0097153 cysteine-type endopeptidase activity involved in apoptotic process IBA
 molecular_functionGO:0097199 cysteine-type endopeptidase activity involved in apoptotic signaling pathway IBA
 molecular_functionGO:0097200 cysteine-type endopeptidase activity involved in execution phase of apoptosis IBA


Pathways (from Reactome)
Pathway description
No match


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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