12374


Mus musculus (NCBI)
ionbindingregulationcalciummembraneg-proteincoupledreceptorplasmasignalingpathwaycellactivitytransportimportintegralcomponentaxonproteinossificationdetectioncellularhomeostasissignaltransductionadenylatecyclase-inhibitingphospholipasec-activatingjnk

Features
Gene ID: 12374
  
Biological name :
  
Synonyms : calcium-sensing receptor / CaR|Gprc2a / Casr
  
Possible biological names infered from orthology :
  
Species: Mus musculus (NCBI)
  
Chr. number:
Strand:
Band:
Gene start:
Gene end:
  
Corresponding Affymetrix probe sets: 1449881_a_at (Mouse Genome 430 2.0 Array)   1449882_a_at (Mouse Genome 430 2.0 Array)   
  
Cross references: RefSeq - 1039750478
RefSeq - 148762954
RefSeq - 568994486
RefSeq - 568994488
RefSeq - 568994490
RefSeq - 568994492
RefSeq - 568994498
RefSeq - NC_000082.6
RefSeq - NP_038831.2
RefSeq - XP_006521792.1
RefSeq - XP_006521793.1
RefSeq - XP_006521794.1
RefSeq - XP_006521795.1
RefSeq - XP_006521798.1
RefSeq - XP_017172345.1
RefSeq - NM_013803.3
RefSeq - XM_017316856.1
RefSeq - XM_006521729.2
RefSeq - XM_006521730.2
RefSeq - XM_006521731.3
RefSeq - XM_006521732.2
RefSeq - XM_006521735.2
  
See co-cited genes in PubMed
Warning: Please see the Ensembl gene model ENSMUSG00000051980 to get all the annotations available for this gene.


Gene Ontology (GO)
ossificationresponse to chemicaldetection of stimulusestablishment of localizationregulation of biological qualitycell communicationcellular response to stimulusnitrogen compound metabolic processresponse to stresscellular metabolic processprimary metabolic processorganic substance metabolic processmacromolecule localizationregulation of molecular functionsystem processanatomical structure developmentresponse to external stimulusossificationresponse to chemicaldetection of stimulusestablishment of localizationregulation of biological qualitycell communicationcellular response to stimulusnitrogen compound metabolic processresponse to stresscellular metabolic processprimary metabolic processorganic substance metabolic processmacromolecule localizationregulation of molecular functionsystem processanatomical structure developmentresponse to external stimulusossificationresponse to chemicaldetection of stimulusestablishment of localizationregulation of biological qualitycell communicationcellular response to stimulusnitrogen compound metabolic processresponse to stresscellular metabolic processprimary metabolic processorganic substance metabolic processmacromolecule localizationregulation of molecular functionsystem processanatomical structure developmentresponse to external stimulusossificationresponse to chemicaldetection of stimulusestablishment of localizationregulation of biological qualitycell communicationcellular response to stimulusnitrogen compound metabolic processresponse to stresscellular metabolic processprimary metabolic processorganic substance metabolic processmacromolecule localizationregulation of molecular functionsystem processanatomical structure developmentresponse to external stimulusossificationresponse to chemicaldetection of stimulusestablishment of localizationregulation of biological qualitycell communicationcellular response to stimulusnitrogen compound metabolic processresponse to stresscellular metabolic processprimary metabolic processorganic substance metabolic processmacromolecule localizationregulation of molecular functionsystem processanatomical structure developmentresponse to external stimulusossificationresponse to chemicaldetection of stimulusestablishment of localizationregulation of biological qualitycell communicationcellular response to stimulusnitrogen compound metabolic processresponse to stresscellular metabolic processprimary metabolic processorganic substance metabolic processmacromolecule localizationregulation of molecular functionsystem processanatomical structure developmentresponse to external stimulusossificationresponse to chemicaldetection of stimulusestablishment of localizationregulation of biological qualitycell communicationcellular response to stimulusnitrogen compound metabolic processresponse to stresscellular metabolic processprimary metabolic processorganic substance metabolic processmacromolecule localizationregulation of molecular functionsystem processanatomical structure developmentresponse to external stimulusossificationresponse to chemicaldetection of stimulusestablishment of localizationregulation of biological qualitycell communicationcellular response to stimulusnitrogen compound metabolic processresponse to stresscellular metabolic processprimary metabolic processorganic substance metabolic processmacromolecule localizationregulation of molecular functionsystem processanatomical structure developmentresponse to external stimulusossificationresponse to chemicaldetection of stimulusestablishment of localizationregulation of biological qualitycell communicationcellular response to stimulusnitrogen compound metabolic processresponse to stresscellular metabolic processprimary metabolic processorganic substance metabolic processmacromolecule localizationregulation of molecular functionsystem processanatomical structure developmentresponse to external stimulusossificationresponse to chemicaldetection of stimulusestablishment of localizationregulation of biological qualitycell communicationcellular response to stimulusnitrogen compound metabolic processresponse to stresscellular metabolic processprimary metabolic processorganic substance metabolic processmacromolecule localizationregulation of molecular functionsystem processanatomical structure developmentresponse to external stimulusossificaossificationresponseresponse to chemicaldetectiodetection of stimulusestablisestablishment of localizationregulatiregulation of biological qualitycell comcell communicationcellularcellular response to stimulusnitrogennitrogen compound metabolic processresponseresponse to stresscellularcellular metabolic processprimary primary metabolic processorganic organic substance metabolic processmacromolmacromolecule localizationregulatiregulation of molecular functionsystem psystem processanatomicanatomical structure developmentresponseresponse to external stimulus
ion bindingsignaling receptor activityprotein bindingprotein-containing complex bindingdrug bindingsmall molecule bindingpolyamine bindingion bindingsignaling receptor activityprotein bindingprotein-containing complex bindingdrug bindingsmall molecule bindingpolyamine bindingion bindingsignaling receptor activityprotein bindingprotein-containing complex bindingdrug bindingsmall molecule bindingpolyamine bindingion bindingsignaling receptor activityprotein bindingprotein-containing complex bindingdrug bindingsmall molecule bindingpolyamine bindingion bindingsignaling receptor activityprotein bindingprotein-containing complex bindingdrug bindingsmall molecule bindingpolyamine bindingion bindingsignaling receptor activityprotein bindingprotein-containing complex bindingdrug bindingsmall molecule bindingpolyamine bindingion bindingsignaling receptor activityprotein bindingprotein-containing complex bindingdrug bindingsmall molecule bindingpolyamine bindingion bindingsignaling receptor activityprotein bindingprotein-containing complex bindingdrug bindingsmall molecule bindingpolyamine bindingion bindingsignaling receptor activityprotein bindingprotein-containing complex bindingdrug bindingsmall molecule bindingpolyamine bindingion bindingsignaling receptor activityprotein bindingprotein-containing complex bindingdrug bindingsmall molecule bindingpolyamine bindingion bindingion bindingsignaling receptor asignaling receptor activityprotein bindingprotein bindingprotein-containing cprotein-containing complex bindingdrug bindingdrug bindingsmall molecule bindismall molecule bindingpolyamine bindingpolyamine binding
cellorganellemembranesynapsecellorganellemembranesynapsecellorganellemembranesynapsecellorganellemembranesynapsecellorganellemembranesynapsecellorganellemembranesynapsecellorganellemembranesynapsecellorganellemembranesynapsecellorganellemembranesynapsecellorganellemembranesynapsecellcellorganelleorganellemembranemembranesynapsesynapse
TypeGO IDTermEv.Code
 biological_processGO:0001503 ossification ISO
 biological_processGO:0005513 detection of calcium ion ISO
 biological_processGO:0006816 calcium ion transport ISO
 biological_processGO:0006874 cellular calcium ion homeostasis ISO
 biological_processGO:0007165 signal transduction IEA
 biological_processGO:0007186 G-protein coupled receptor signaling pathway ISO
 biological_processGO:0007193 adenylate cyclase-inhibiting G-protein coupled receptor signaling pathway ISO
 biological_processGO:0007200 phospholipase C-activating G-protein coupled receptor signaling pathway ISO
 biological_processGO:0007254 JNK cascade ISO
 biological_processGO:0008284 positive regulation of cell proliferation ISO
 biological_processGO:0010628 positive regulation of gene expression IDA
 biological_processGO:0032024 positive regulation of insulin secretion ISO
 biological_processGO:0032781 positive regulation of ATPase activity IMP
 biological_processGO:0042311 vasodilation ISO
 biological_processGO:0045907 positive regulation of vasoconstriction ISO
 biological_processGO:0048754 branching morphogenesis of an epithelial tube ISO
 biological_processGO:0050927 positive regulation of positive chemotaxis ISO
 biological_processGO:0051924 regulation of calcium ion transport IDA
 biological_processGO:0070509 calcium ion import ISO
 biological_processGO:0090280 positive regulation of calcium ion import ISO
 cellular_componentGO:0005634 nucleus ISO
 cellular_componentGO:0005737 cytoplasm ISO
 cellular_componentGO:0005886 plasma membrane ISO
 cellular_componentGO:0005887 integral component of plasma membrane ISO
 cellular_componentGO:0009986 cell surface ISO
 cellular_componentGO:0016020 membrane ISO
 cellular_componentGO:0016021 integral component of membrane IEA
 cellular_componentGO:0016323 basolateral plasma membrane ISO
 cellular_componentGO:0016324 apical plasma membrane ISO
 cellular_componentGO:0030424 axon ISO
 cellular_componentGO:0043005 neuron projection ISO
 cellular_componentGO:0043025 neuronal cell body ISO
 cellular_componentGO:0043679 axon terminus ISO
 molecular_functionGO:0000287 magnesium ion binding ISO
 molecular_functionGO:0004930 G-protein coupled receptor activity ISO
 molecular_functionGO:0005178 integrin binding ISO
 molecular_functionGO:0005509 calcium ion binding ISO
 molecular_functionGO:0008144 drug binding ISO
 molecular_functionGO:0016597 amino acid binding ISO
 molecular_functionGO:0019808 polyamine binding ISO
 molecular_functionGO:0019901 protein kinase binding ISO
 molecular_functionGO:0042803 protein homodimerization activity ISO
 molecular_functionGO:0044325 ion channel binding ISO
 molecular_functionGO:0046872 metal ion binding IEA


Pathways (from Reactome)
Pathway description
No match


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

0 s.

 
External programs and data are copyrighted by and are the property of their respective authors.
The Manteia system, data and analyses are provided "as is" with no warranties, expressed or implied as to capabilities or accuracy. User assumes the entire risk as to the results and performance of the software, data and documentation


                   


© Olivier Tassy / Olivier Pourquie 2007-2025
contact: otassy@igbmc.fr