12393


Mus musculus (NCBI)

Features
Gene ID: 12393
  
Biological name :
  
Synonyms : AML3|Cbf|Cbfa-1|Cbfa1|LS3|Osf2|PEBP2aA|Pebp2a1|Pebpa2a / runt related transcription factor 2 / Runx2
  
Possible biological names infered from orthology :
  
Species: Mus musculus (NCBI)
  
Chr. number:
Strand:
Band:
Gene start:
Gene end:
  
Corresponding Affymetrix probe sets: 1424704_at (Mouse Genome 430 2.0 Array)   1425389_a_at (Mouse Genome 430 2.0 Array)   1426034_a_at (Mouse Genome 430 2.0 Array)   
  
Cross references: RefSeq - 568998773
RefSeq - 568998775
RefSeq - 568998777
RefSeq - 568998779
RefSeq - 568998781
RefSeq - NC_000083.6
RefSeq - 225690634
RefSeq - 226437618
RefSeq - 410110923
RefSeq - XP_006523603.1
RefSeq - XP_006523604.1
RefSeq - XP_006523605.1
RefSeq - XP_006523606.1
RefSeq - XP_006523607.1
RefSeq - XP_006523608.1
RefSeq - XP_006523609.1
RefSeq - XP_006523610.1
RefSeq - XP_006523611.1
RefSeq - 410110932
RefSeq - 410110934
RefSeq - 225690526
RefSeq - 568998765
RefSeq - 568998767
RefSeq - NP_001139392.1
RefSeq - NP_001139510.1
RefSeq - NP_001258556.1
RefSeq - NP_001258559.1
RefSeq - NP_001258560.1
RefSeq - NP_033950.2
RefSeq - 568998769
RefSeq - 568998771
RefSeq - XR_385274.2
RefSeq - NM_001145920.2
RefSeq - NM_001146038.2
RefSeq - NM_001271627.1
RefSeq - NM_001271630.1
RefSeq - NM_001271631.1
RefSeq - NM_001271633.1
RefSeq - NM_009820.5
RefSeq - NR_073392.1
RefSeq - NR_073425.1
RefSeq - XM_006523540.2
RefSeq - XM_006523541.2
RefSeq - XM_006523542.2
RefSeq - XM_006523543.2
RefSeq - XM_006523544.2
RefSeq - XM_006523545.2
RefSeq - XM_006523546.2
RefSeq - XM_006523547.2
RefSeq - XM_006523548.2
RefSeq - XR_385271.2
RefSeq - XR_385272.3
  
See co-cited genes in PubMed
Warning: Please see the Ensembl gene model ENSMUSG00000039153 to get all the annotations available for this gene.


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0001501 skeletal system development IMP
 biological_processGO:0001649 osteoblast differentiation ISO
 biological_processGO:0001958 endochondral ossification IMP
 biological_processGO:0002051 osteoblast fate commitment IGI
 biological_processGO:0002062 chondrocyte differentiation IMP
 biological_processGO:0002063 chondrocyte development IMP
 biological_processGO:0002076 osteoblast development IGI
 biological_processGO:0006351 transcription, DNA-templated IEA
 biological_processGO:0006355 regulation of transcription, DNA-templated IEA
 biological_processGO:0006357 regulation of transcription by RNA polymerase II IBA
 biological_processGO:0008284 positive regulation of cell proliferation IMP
 biological_processGO:0010628 positive regulation of gene expression IDA
 biological_processGO:0030097 hemopoiesis IBA
 biological_processGO:0030154 cell differentiation IEA
 biological_processGO:0030182 neuron differentiation IBA
 biological_processGO:0030217 T cell differentiation IDA
 biological_processGO:0030278 regulation of ossification IMP
 biological_processGO:0030509 BMP signaling pathway IMP
 biological_processGO:0032332 positive regulation of chondrocyte differentiation IMP
 biological_processGO:0035115 embryonic forelimb morphogenesis IMP
 biological_processGO:0040036 regulation of fibroblast growth factor receptor signaling pathway IMP
 biological_processGO:0042475 odontogenesis of dentin-containing tooth IMP
 biological_processGO:0042487 regulation of odontogenesis of dentin-containing tooth IMP
 biological_processGO:0045595 regulation of cell differentiation IBA
 biological_processGO:0045667 regulation of osteoblast differentiation IDA
 biological_processGO:0045669 positive regulation of osteoblast differentiation ISO
 biological_processGO:0045778 positive regulation of ossification ISO
 biological_processGO:0045879 negative regulation of smoothened signaling pathway IMP
 biological_processGO:0045892 negative regulation of transcription, DNA-templated ISO
 biological_processGO:0045893 positive regulation of transcription, DNA-templated ISO
 biological_processGO:0045944 positive regulation of transcription by RNA polymerase II ISO
 biological_processGO:0048469 cell maturation IMP
 biological_processGO:0048701 embryonic cranial skeleton morphogenesis IGI
 biological_processGO:0048705 skeletal system morphogenesis IMP
 biological_processGO:0048863 stem cell differentiation IDA
 biological_processGO:0071773 cellular response to BMP stimulus IMP
 biological_processGO:1901522 positive regulation of transcription from RNA polymerase II promoter involved in cellular response to chemical stimulus IMP
 cellular_componentGO:0000790 nuclear chromatin IDA
 cellular_componentGO:0005634 nucleus ISO
 cellular_componentGO:0005654 nucleoplasm ISO
 cellular_componentGO:0005667 transcription factor complex IDA
 cellular_componentGO:0005737 cytoplasm IDA
 cellular_componentGO:0032991 protein-containing complex ISO
 molecular_functionGO:0000978 RNA polymerase II proximal promoter sequence-specific DNA binding IDA
 molecular_functionGO:0000981 RNA polymerase II transcription factor activity, sequence-specific DNA binding IBA
 molecular_functionGO:0001077 transcriptional activator activity, RNA polymerase II proximal promoter sequence-specific DNA binding IDA
 molecular_functionGO:0003677 DNA binding IGI
 molecular_functionGO:0003682 chromatin binding IDA
 molecular_functionGO:0003700 DNA-binding transcription factor activity TAS
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0005524 ATP binding IEA
 molecular_functionGO:0008134 transcription factor binding ISO
 molecular_functionGO:0019904 protein domain specific binding IPI
 molecular_functionGO:0042826 histone deacetylase binding ISO
 molecular_functionGO:0043425 bHLH transcription factor binding IPI
 molecular_functionGO:0044212 transcription regulatory region DNA binding IDA
 molecular_functionGO:0070491 repressing transcription factor binding IPI


Pathways (from Reactome)
Pathway description
No match


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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