12394


Mus musculus (NCBI)

Features
Gene ID: 12394
  
Biological name :
  
Synonyms : AML1|CBF-alpha-2|Cbfa2|Pebp2a2|Pebpa2b / runt related transcription factor 1 / Runx1
  
Possible biological names infered from orthology :
  
Species: Mus musculus (NCBI)
  
Chr. number:
Strand:
Band:
Gene start:
Gene end:
  
Corresponding Affymetrix probe sets: 1422864_at (Mouse Genome 430 2.0 Array)   1422865_at (Mouse Genome 430 2.0 Array)   1427650_a_at (Mouse Genome 430 2.0 Array)   1440878_at (Mouse Genome 430 2.0 Array)   1452530_a_at (Mouse Genome 430 2.0 Array)   1452531_at (Mouse Genome 430 2.0 Array)   
  
Cross references: RefSeq - 161169025
RefSeq - 161169027
RefSeq - 161169029
RefSeq - 161169031
RefSeq - NC_000082.6
RefSeq - NP_001104491.1
RefSeq - NP_001104492.1
RefSeq - NP_001104493.1
RefSeq - NP_033951.2
RefSeq - NM_001111021.2
RefSeq - NM_001111022.2
RefSeq - NM_001111023.2
RefSeq - NM_009821.3
  
See co-cited genes in PubMed
Warning: Please see the Ensembl gene model ENSMUSG00000022952 to get all the annotations available for this gene.


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0000122 negative regulation of transcription by RNA polymerase II IDA
 biological_processGO:0001501 skeletal system development IMP
 biological_processGO:0001701 in utero embryonic development IMP
 biological_processGO:0001889 liver development IMP
 biological_processGO:0002318 myeloid progenitor cell differentiation IMP
 biological_processGO:0002667 regulation of T cell anergy IMP
 biological_processGO:0006351 transcription, DNA-templated IEA
 biological_processGO:0006355 regulation of transcription, DNA-templated IDA
 biological_processGO:0006357 regulation of transcription by RNA polymerase II IBA
 biological_processGO:0007417 central nervous system development IMP
 biological_processGO:0008285 negative regulation of cell proliferation IMP
 biological_processGO:0009966 regulation of signal transduction IMP
 biological_processGO:0030097 hemopoiesis TAS
 biological_processGO:0030099 myeloid cell differentiation ISO
 biological_processGO:0030182 neuron differentiation IMP
 biological_processGO:0030853 negative regulation of granulocyte differentiation ISO
 biological_processGO:0030854 positive regulation of granulocyte differentiation ISO
 biological_processGO:0031069 hair follicle morphogenesis IMP
 biological_processGO:0032526 response to retinoic acid IDA
 biological_processGO:0032729 positive regulation of interferon-gamma production IDA
 biological_processGO:0032743 positive regulation of interleukin-2 production ISO
 biological_processGO:0035162 embryonic hemopoiesis IMP
 biological_processGO:0043371 negative regulation of CD4-positive, alpha-beta T cell differentiation IDA
 biological_processGO:0043378 positive regulation of CD8-positive, alpha-beta T cell differentiation IDA
 biological_processGO:0045595 regulation of cell differentiation IBA
 biological_processGO:0045766 positive regulation of angiogenesis IMP
 biological_processGO:0045892 negative regulation of transcription, DNA-templated IDA
 biological_processGO:0045893 positive regulation of transcription, DNA-templated ISO
 biological_processGO:0045944 positive regulation of transcription by RNA polymerase II ISO
 biological_processGO:0048266 behavioral response to pain IMP
 biological_processGO:0048663 neuron fate commitment IMP
 biological_processGO:0048666 neuron development IMP
 biological_processGO:0060216 definitive hemopoiesis IMP
 biological_processGO:0071336 regulation of hair follicle cell proliferation IMP
 biological_processGO:0071560 cellular response to transforming growth factor beta stimulus IDA
 biological_processGO:1903431 positive regulation of cell maturation IMP
 biological_processGO:2000872 positive regulation of progesterone secretion ISO
 cellular_componentGO:0005604 basement membrane IDA
 cellular_componentGO:0005634 nucleus ISO
 cellular_componentGO:0005654 nucleoplasm ISO
 cellular_componentGO:0005829 cytosol ISO
 cellular_componentGO:0016513 core-binding factor complex TAS
 cellular_componentGO:0032991 protein-containing complex ISO
 cellular_componentGO:0043231 intracellular membrane-bounded organelle ISO
 molecular_functionGO:0000977 RNA polymerase II regulatory region sequence-specific DNA binding ISO
 molecular_functionGO:0000978 RNA polymerase II proximal promoter sequence-specific DNA binding ISO
 molecular_functionGO:0000981 RNA polymerase II transcription factor activity, sequence-specific DNA binding IBA
 molecular_functionGO:0001228 transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific DNA binding ISO
 molecular_functionGO:0003677 DNA binding ISO
 molecular_functionGO:0003700 DNA-binding transcription factor activity ISO
 molecular_functionGO:0005509 calcium ion binding ISO
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0005524 ATP binding IEA
 molecular_functionGO:0008134 transcription factor binding ISO
 molecular_functionGO:0042803 protein homodimerization activity ISO
 molecular_functionGO:0044212 transcription regulatory region DNA binding ISO
 molecular_functionGO:0046982 protein heterodimerization activity ISO
 molecular_functionGO:0070491 repressing transcription factor binding IPI
 molecular_functionGO:1990837 sequence-specific double-stranded DNA binding ISO
 molecular_functionGO:1990841 promoter-specific chromatin binding ISO


Pathways (from Reactome)
Pathway description
No match


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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