12575


Mus musculus (NCBI)

Features
Gene ID: 12575
  
Biological name :
  
Synonyms : CAP20|CDKI|CIP1|Cdkn1|P21|SDI1|Waf1|mda6|p21Cip1|p21WAF / Cdkn1a / cyclin-dependent kinase inhibitor 1A (P21)
  
Possible biological names infered from orthology :
  
Species: Mus musculus (NCBI)
  
Chr. number:
Strand:
Band:
Gene start:
Gene end:
  
Corresponding Affymetrix probe sets: 1421679_a_at (Mouse Genome 430 2.0 Array)   1424638_at (Mouse Genome 430 2.0 Array)   
  
Cross references: RefSeq - 162287333
RefSeq - 6671726
RefSeq - NC_000083.6
RefSeq - NP_031695.1
RefSeq - NT_187005.1
RefSeq - NP_001104569.1
RefSeq - NM_001111099.2
RefSeq - NM_007669.5
  
See co-cited genes in PubMed
Warning: Please see the Ensembl gene model ENSMUSG00000023067 to get all the annotations available for this gene.


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0000079 regulation of cyclin-dependent protein serine/threonine kinase activity IMP
 biological_processGO:0000082 G1/S transition of mitotic cell cycle ISO
 biological_processGO:0000086 G2/M transition of mitotic cell cycle ISO
 biological_processGO:0006974 cellular response to DNA damage stimulus ISO
 biological_processGO:0006977 DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest ISO
 biological_processGO:0006978 DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator IDA
 biological_processGO:0007049 cell cycle IEA
 biological_processGO:0007050 cell cycle arrest ISO
 biological_processGO:0007346 regulation of mitotic cell cycle IMP
 biological_processGO:0008285 negative regulation of cell proliferation ISO
 biological_processGO:0009411 response to UV IMP
 biological_processGO:0010629 negative regulation of gene expression IMP
 biological_processGO:0010942 positive regulation of cell death ISO
 biological_processGO:0030308 negative regulation of cell growth ISO
 biological_processGO:0030890 positive regulation of B cell proliferation IGI
 biological_processGO:0031668 cellular response to extracellular stimulus ISO
 biological_processGO:0033158 regulation of protein import into nucleus, translocation IMP
 biological_processGO:0034198 cellular response to amino acid starvation ISO
 biological_processGO:0042326 negative regulation of phosphorylation ISO
 biological_processGO:0042771 intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator IMP
 biological_processGO:0043066 negative regulation of apoptotic process ISO
 biological_processGO:0043068 positive regulation of programmed cell death IMP
 biological_processGO:0045736 negative regulation of cyclin-dependent protein serine/threonine kinase activity IDA
 biological_processGO:0045860 positive regulation of protein kinase activity ISO
 biological_processGO:0048146 positive regulation of fibroblast proliferation ISO
 biological_processGO:0051726 regulation of cell cycle IDA
 biological_processGO:0071479 cellular response to ionizing radiation ISO
 biological_processGO:0071480 cellular response to gamma radiation IDA
 biological_processGO:0071493 cellular response to UV-B IDA
 biological_processGO:0071850 mitotic cell cycle arrest IDA
 biological_processGO:0072331 signal transduction by p53 class mediator IEA
 biological_processGO:0090398 cellular senescence ISO
 biological_processGO:1904030 negative regulation of cyclin-dependent protein kinase activity ISO
 biological_processGO:1904706 negative regulation of vascular smooth muscle cell proliferation ISO
 biological_processGO:2000134 negative regulation of G1/S transition of mitotic cell cycle ISO
 biological_processGO:2000278 regulation of DNA biosynthetic process IMP
 biological_processGO:2000379 positive regulation of reactive oxygen species metabolic process ISO
 cellular_componentGO:0000307 cyclin-dependent protein kinase holoenzyme complex ISO
 cellular_componentGO:0005634 nucleus ISO
 cellular_componentGO:0005654 nucleoplasm ISO
 cellular_componentGO:0005730 nucleolus ISO
 cellular_componentGO:0005737 cytoplasm ISO
 cellular_componentGO:0005829 cytosol IDA
 cellular_componentGO:0016604 nuclear body ISO
 cellular_componentGO:0032991 protein-containing complex ISO
 cellular_componentGO:0048471 perinuclear region of cytoplasm ISO
 cellular_componentGO:0070557 PCNA-p21 complex ISO
 molecular_functionGO:0004693 cyclin-dependent protein serine/threonine kinase activity ISO
 molecular_functionGO:0004860 protein kinase inhibitor activity ISO
 molecular_functionGO:0004861 cyclin-dependent protein serine/threonine kinase inhibitor activity IDA
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0019901 protein kinase binding ISO
 molecular_functionGO:0019912 cyclin-dependent protein kinase activating kinase activity ISO
 molecular_functionGO:0030332 cyclin binding IDA
 molecular_functionGO:0031625 ubiquitin protein ligase binding ISO
 molecular_functionGO:0044877 protein-containing complex binding ISO
 molecular_functionGO:0046872 metal ion binding IEA


Pathways (from Reactome)
Pathway description
No match


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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