12675


Mus musculus (NCBI)

Features
Gene ID: 12675
  
Biological name :
  
Synonyms : AI256658|Chuk1|Fbx24|Fbxo24|IKBKA|IKK alpha|IKK1|Ikka|NFKBIKA / Chuk / conserved helix-loop-helix ubiquitous kinase
  
Possible biological names infered from orthology :
  
Species: Mus musculus (NCBI)
  
Chr. number:
Strand:
Band:
Gene start:
Gene end:
  
Corresponding Affymetrix probe sets: 1417091_at (Mouse Genome 430 2.0 Array)   1428210_s_at (Mouse Genome 430 2.0 Array)   1451383_a_at (Mouse Genome 430 2.0 Array)   
  
Cross references: RefSeq - 242332488
RefSeq - 242332490
RefSeq - 755562724
RefSeq - NC_000085.6
RefSeq - NP_001155882.1
RefSeq - NP_031726.2
RefSeq - XP_011245431.1
RefSeq - XR_001782557.1
RefSeq - XM_011247129.2
RefSeq - NM_001162410.1
RefSeq - NM_007700.2
RefSeq - XR_001782558.1
  
See co-cited genes in PubMed
Warning: Please see the Ensembl gene model ENSMUSG00000025199 to get all the annotations available for this gene.


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0002011 morphogenesis of an epithelial sheet IMP
 biological_processGO:0006468 protein phosphorylation ISO
 biological_processGO:0007249 I-kappaB kinase/NF-kappaB signaling ISO
 biological_processGO:0007252 I-kappaB phosphorylation TAS
 biological_processGO:0007266 Rho protein signal transduction ISO
 biological_processGO:0007595 lactation IMP
 biological_processGO:0009653 anatomical structure morphogenesis IBA
 biological_processGO:0010033 response to organic substance ISO
 biological_processGO:0016310 phosphorylation IEA
 biological_processGO:0018105 peptidyl-serine phosphorylation IBA
 biological_processGO:0030316 osteoclast differentiation IMP
 biological_processGO:0032088 negative regulation of NF-kappaB transcription factor activity ISO
 biological_processGO:0032496 response to lipopolysaccharide ISO
 biological_processGO:0033209 tumor necrosis factor-mediated signaling pathway IBA
 biological_processGO:0033598 mammary gland epithelial cell proliferation IMP
 biological_processGO:0034614 cellular response to reactive oxygen species ISO
 biological_processGO:0035994 response to muscle stretch IMP
 biological_processGO:0038061 NIK/NF-kappaB signaling ISO
 biological_processGO:0042475 odontogenesis of dentin-containing tooth IMP
 biological_processGO:0043123 positive regulation of I-kappaB kinase/NF-kappaB signaling IMP
 biological_processGO:0045893 positive regulation of transcription, DNA-templated ISO
 biological_processGO:0045944 positive regulation of transcription by RNA polymerase II ISO
 biological_processGO:0051092 positive regulation of NF-kappaB transcription factor activity IBA
 biological_processGO:0051146 striated muscle cell differentiation ISO
 biological_processGO:0051607 defense response to virus IMP
 biological_processGO:0060749 mammary gland alveolus development IMP
 biological_processGO:0071276 cellular response to cadmium ion ISO
 biological_processGO:0071356 cellular response to tumor necrosis factor ISO
 biological_processGO:0098586 cellular response to virus ISO
 biological_processGO:1902741 positive regulation of interferon-alpha secretion ISO
 cellular_componentGO:0005634 nucleus IEA
 cellular_componentGO:0005654 nucleoplasm ISO
 cellular_componentGO:0005737 cytoplasm TAS
 cellular_componentGO:0005829 cytosol ISO
 cellular_componentGO:0008385 IkappaB kinase complex ISO
 cellular_componentGO:0009898 cytoplasmic side of plasma membrane IDA
 cellular_componentGO:0035631 CD40 receptor complex IDA
 cellular_componentGO:0043231 intracellular membrane-bounded organelle ISO
 molecular_functionGO:0000166 nucleotide binding IEA
 molecular_functionGO:0004672 protein kinase activity ISO
 molecular_functionGO:0004674 protein serine/threonine kinase activity IEA
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0005524 ATP binding IEA
 molecular_functionGO:0008384 IkappaB kinase activity ISO
 molecular_functionGO:0016301 kinase activity IEA
 molecular_functionGO:0016740 transferase activity IEA
 molecular_functionGO:0042802 identical protein binding ISO
 molecular_functionGO:0042803 protein homodimerization activity ISO
 molecular_functionGO:0046982 protein heterodimerization activity ISO
 molecular_functionGO:0097110 scaffold protein binding ISO


Pathways (from Reactome)
Pathway description
No match


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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