1268


Homo sapiens (NCBI)
regulationresponsesignalingmembranecoupledreceptorpathwayg-proteinsynaptictransmissionsecretioncannabinoidprocessbloodpressureactivityplasmabindingacuteinflammatoryantigenicstimuluscyclicnucleotidesecondmessengeradenylatecyclase-modulatingspermatogenesisaxonal

Features
Gene ID: 1268
  
Biological name :
  
Synonyms : CANN6|CB-R|CB1|CB1A|CB1K5|CB1R|CNR / cannabinoid receptor 1 / CNR1
  
Possible biological names infered from orthology :
  
Species: Homo sapiens (NCBI)
  
Chr. number:
Strand:
Band:
Gene start:
Gene end:
  
Corresponding Affymetrix probe sets: 1560225_at (Human Genome U133 Plus 2.0 Array)   207940_x_at (Human Genome U133 Plus 2.0 Array)   208243_s_at (Human Genome U133 Plus 2.0 Array)   213436_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: RefSeq - XP_024302096.1
RefSeq - 1370507332
RefSeq - 237681065
RefSeq - 237681067
RefSeq - 237681173
RefSeq - 237681175
RefSeq - 38683844
RefSeq - 578812380
RefSeq - 767941862
RefSeq - 767941864
RefSeq - 767941866
RefSeq - 767941870
RefSeq - NC_000006.12
RefSeq - NP_001153698.1
RefSeq - NP_001153730.1
RefSeq - NP_001153731.1
RefSeq - NP_057167.2
RefSeq - NP_149421.2
RefSeq - XP_006715393.1
RefSeq - XP_011533726.1
RefSeq - XP_011533727.1
RefSeq - XP_011533728.1
RefSeq - XP_011533730.1
RefSeq - XP_016865729.1
RefSeq - 1034648400
RefSeq - XM_011535424.2
RefSeq - NM_001160226.1
RefSeq - NM_001160258.1
RefSeq - NM_001160259.1
RefSeq - NM_001160260.1
RefSeq - NM_016083.4
RefSeq - NM_033181.3
RefSeq - XM_011535425.2
RefSeq - XM_011535426.2
RefSeq - XM_011535428.2
RefSeq - XM_017010240.2
RefSeq - XM_024446328.1
RefSeq - XM_006715330.3
  
See co-cited genes in PubMed
Warning: Please see the Ensembl gene model ENSG00000118432 to get all the annotations available for this gene.


Gene Ontology (GO)
response to stressimmune responseresponse to external stimuluscell communicationcellular response to stimulusmulticellular organism reproductioncell recognitioncellular component organizationanatomical structure developmentcellular developmental processagingresponse to chemicalsystem processregulation of biological qualitycatabolic processcellular metabolic processprimary metabolic processsmall molecule metabolic processorganic substance metabolic processoxidation-reduction processresponse to biotic stimuluscell activationestablishment of localizationcell deathmacromolecule localizationregulation of molecular functionmulti-multicellular organism processfeeding behaviorresponse to stressimmune responseresponse to external stimuluscell communicationcellular response to stimulusmulticellular organism reproductioncell recognitioncellular component organizationanatomical structure developmentcellular developmental processagingresponse to chemicalsystem processregulation of biological qualitycatabolic processcellular metabolic processprimary metabolic processsmall molecule metabolic processorganic substance metabolic processoxidation-reduction processresponse to biotic stimuluscell activationestablishment of localizationcell deathmacromolecule localizationregulation of molecular functionmulti-multicellular organism processfeeding behaviorresponse to stressimmune responseresponse to external stimuluscell communicationcellular response to stimulusmulticellular organism reproductioncell recognitioncellular component organizationanatomical structure developmentcellular developmental processagingresponse to chemicalsystem processregulation of biological qualitycatabolic processcellular metabolic processprimary metabolic processsmall molecule metabolic processorganic substance metabolic processoxidation-reduction processresponse to biotic stimuluscell activationestablishment of localizationcell deathmacromolecule localizationregulation of molecular functionmulti-multicellular organism processfeeding behaviorresponse to stressimmune responseresponse to external stimuluscell communicationcellular response to stimulusmulticellular organism reproductioncell recognitioncellular component organizationanatomical structure developmentcellular developmental processagingresponse to chemicalsystem processregulation of biological qualitycatabolic processcellular metabolic processprimary metabolic processsmall molecule metabolic processorganic substance metabolic processoxidation-reduction processresponse to biotic stimuluscell activationestablishment of localizationcell deathmacromolecule localizationregulation of molecular functionmulti-multicellular organism processfeeding behaviorresponse to stressimmune responseresponse to external stimuluscell communicationcellular response to stimulusmulticellular organism reproductioncell recognitioncellular component organizationanatomical structure developmentcellular developmental processagingresponse to chemicalsystem processregulation of biological qualitycatabolic processcellular metabolic processprimary metabolic processsmall molecule metabolic processorganic substance metabolic processoxidation-reduction processresponse to biotic stimuluscell activationestablishment of localizationcell deathmacromolecule localizationregulation of molecular functionmulti-multicellular organism processfeeding behaviorresponse to stressimmune responseresponse to external stimuluscell communicationcellular response to stimulusmulticellular organism reproductioncell recognitioncellular component organizationanatomical structure developmentcellular developmental processagingresponse to chemicalsystem processregulation of biological qualitycatabolic processcellular metabolic processprimary metabolic processsmall molecule metabolic processorganic substance metabolic processoxidation-reduction processresponse to biotic stimuluscell activationestablishment of localizationcell deathmacromolecule localizationregulation of molecular functionmulti-multicellular organism processfeeding behaviorresponse to stressimmune responseresponse to external stimuluscell communicationcellular response to stimulusmulticellular organism reproductioncell recognitioncellular component organizationanatomical structure developmentcellular developmental processagingresponse to chemicalsystem processregulation of biological qualitycatabolic processcellular metabolic processprimary metabolic processsmall molecule metabolic processorganic substance metabolic processoxidation-reduction processresponse to biotic stimuluscell activationestablishment of localizationcell deathmacromolecule localizationregulation of molecular functionmulti-multicellular organism processfeeding behaviorresponse to stressimmune responseresponse to external stimuluscell communicationcellular response to stimulusmulticellular organism reproductioncell recognitioncellular component organizationanatomical structure developmentcellular developmental processagingresponse to chemicalsystem processregulation of biological qualitycatabolic processcellular metabolic processprimary metabolic processsmall molecule metabolic processorganic substance metabolic processoxidation-reduction processresponse to biotic stimuluscell activationestablishment of localizationcell deathmacromolecule localizationregulation of molecular functionmulti-multicellular organism processfeeding behaviorresponse to stressimmune responseresponse to external stimuluscell communicationcellular response to stimulusmulticellular organism reproductioncell recognitioncellular component organizationanatomical structure developmentcellular developmental processagingresponse to chemicalsystem processregulation of biological qualitycatabolic processcellular metabolic processprimary metabolic processsmall molecule metabolic processorganic substance metabolic processoxidation-reduction processresponse to biotic stimuluscell activationestablishment of localizationcell deathmacromolecule localizationregulation of molecular functionmulti-multicellular organism processfeeding behaviorresponse to stressimmune responseresponse to external stimuluscell communicationcellular response to stimulusmulticellular organism reproductioncell recognitioncellular component organizationanatomical structure developmentcellular developmental processagingresponse to chemicalsystem processregulation of biological qualitycatabolic processcellular metabolic processprimary metabolic processsmall molecule metabolic processorganic substance metabolic processoxidation-reduction processresponse to biotic stimuluscell activationestablishment of localizationcell deathmacromolecule localizationregulation of molecular functionmulti-multicellular organism processfeeding behaviorresporesponse to stressimmunimmune responseresporesponse to external stimuluscell cell communicationcellucellular response to stimulusmultimulticellular organism reproductioncell cell recognitioncellucellular component organizationanatoanatomical structure developmentcellucellular developmental processagingagingresporesponse to chemicalsystesystem processregulregulation of biological qualitycatabcatabolic processcellucellular metabolic processprimaprimary metabolic processsmallsmall molecule metabolic processorganorganic substance metabolic processoxidaoxidation-reduction processresporesponse to biotic stimuluscell cell activationestabestablishment of localizationcell cell deathmacromacromolecule localizationregulregulation of molecular functionmultimulti-multicellular organism processfeedifeeding behavior
signaling receptor activityprotein bindingdrug bindingsignaling receptor activityprotein bindingdrug bindingsignaling receptor activityprotein bindingdrug bindingsignaling receptor activityprotein bindingdrug bindingsignaling receptor activityprotein bindingdrug bindingsignaling receptor activityprotein bindingdrug bindingsignaling receptor activityprotein bindingdrug bindingsignaling receptor activityprotein bindingdrug bindingsignaling receptor activityprotein bindingdrug bindingsignaling receptor activityprotein bindingdrug bindingsignaling receptor activitysignaling receptor activityprotein bindingprotein bindingdrug bindingdrug binding
cellmembraneorganellesynapsecellmembraneorganellesynapsecellmembraneorganellesynapsecellmembraneorganellesynapsecellmembraneorganellesynapsecellmembraneorganellesynapsecellmembraneorganellesynapsecellmembraneorganellesynapsecellmembraneorganellesynapsecellmembraneorganellesynapsecellcellmembranemembraneorganelleorganellesynapsesynapse
TypeGO IDTermEv.Code
 biological_processGO:0002866 positive regulation of acute inflammatory response to antigenic stimulus IEA
 biological_processGO:0007186 G-protein coupled receptor signaling pathway TAS
 biological_processGO:0007187 G-protein coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger TAS
 biological_processGO:0007188 adenylate cyclase-modulating G-protein coupled receptor signaling pathway IDA
 biological_processGO:0007283 spermatogenesis IEA
 biological_processGO:0007413 axonal fasciculation IEA
 biological_processGO:0007568 aging IEA
 biological_processGO:0007584 response to nutrient IEA
 biological_processGO:0007613 memory IEA
 biological_processGO:0010976 positive regulation of neuron projection development IEA
 biological_processGO:0019233 sensory perception of pain IEA
 biological_processGO:0031622 positive regulation of fever generation IEA
 biological_processGO:0031999 negative regulation of fatty acid beta-oxidation IEA
 biological_processGO:0032228 regulation of synaptic transmission, GABAergic IEA
 biological_processGO:0032496 response to lipopolysaccharide IEA
 biological_processGO:0033004 negative regulation of mast cell activation IEA
 biological_processGO:0033602 negative regulation of dopamine secretion IEA
 biological_processGO:0035094 response to nicotine IEA
 biological_processGO:0038171 cannabinoid signaling pathway IDA
 biological_processGO:0042220 response to cocaine IEA
 biological_processGO:0042593 glucose homeostasis IEA
 biological_processGO:0043065 positive regulation of apoptotic process IEA
 biological_processGO:0043278 response to morphine IEA
 biological_processGO:0045471 response to ethanol IEA
 biological_processGO:0045759 negative regulation of action potential IEA
 biological_processGO:0045776 negative regulation of blood pressure IEA
 biological_processGO:0045777 positive regulation of blood pressure IEA
 biological_processGO:0050796 regulation of insulin secretion IEA
 biological_processGO:0051001 negative regulation of nitric-oxide synthase activity IEA
 biological_processGO:0051966 regulation of synaptic transmission, glutamatergic IEA
 biological_processGO:0060135 maternal process involved in female pregnancy IEA
 biological_processGO:0060259 regulation of feeding behavior IEA
 biological_processGO:0060405 regulation of penile erection IEA
 biological_processGO:0099553 trans-synaptic signaling by endocannabinoid, modulating synaptic transmission IEA
 cellular_componentGO:0005741 mitochondrial outer membrane IEA
 cellular_componentGO:0005886 plasma membrane TAS
 cellular_componentGO:0005887 integral component of plasma membrane TAS
 cellular_componentGO:0030426 growth cone IEA
 cellular_componentGO:0042734 presynaptic membrane IEA
 cellular_componentGO:0045121 membrane raft IEA
 molecular_functionGO:0004949 cannabinoid receptor activity IDA
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0008144 drug binding IEA


Pathways (from Reactome)
Pathway description
No match


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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