ENSG00000118432


Homo sapiens

Features
Gene ID: ENSG00000118432
  
Biological name :CNR1
  
Synonyms : cannabinoid receptor 1 / CNR1 / P21554
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 6
Strand: -1
Band: q15
Gene start: 88139864
Gene end: 88166359
  
Corresponding Affymetrix probe sets: 1560225_at (Human Genome U133 Plus 2.0 Array)   207940_x_at (Human Genome U133 Plus 2.0 Array)   208243_s_at (Human Genome U133 Plus 2.0 Array)   213436_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000446819
Ensembl peptide - ENSP00000420188
Ensembl peptide - ENSP00000446702
Ensembl peptide - ENSP00000355418
Ensembl peptide - ENSP00000358511
Ensembl peptide - ENSP00000358513
Ensembl peptide - ENSP00000412192
NCBI entrez gene - 1268     See in Manteia.
OMIM - 114610
RefSeq - XM_017010240
RefSeq - NM_001160259
RefSeq - NM_016083
RefSeq - NM_033181
RefSeq - XM_006715330
RefSeq - XM_011535424
RefSeq - XM_011535425
RefSeq - XM_011535426
RefSeq - XM_011535428
RefSeq - XM_017010238
RefSeq - XM_017010239
RefSeq - NM_001160226
RefSeq - NM_001160258
RefSeq Peptide - NP_149421
RefSeq Peptide - NP_001153698
RefSeq Peptide - NP_001153730
RefSeq Peptide - NP_001153731
RefSeq Peptide - NP_057167
swissprot - F8W187
swissprot - P21554
swissprot - S5TLS4
swissprot - V5KA96
swissprot - F8W908
Ensembl - ENSG00000118432
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 cnr1ENSDARG00000009020Danio rerio
 CNR1ENSGALG00000037511Gallus gallus
 Cnr1ENSMUSG00000044288Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
CNR2 / P34972 / cannabinoid receptor 2ENSG0000018882232
S1PR3 / Q99500 / sphingosine-1-phosphate receptor 3ENSG0000021369419
LPAR1 / Q92633 / lysophosphatidic acid receptor 1ENSG0000019812119
S1PR1 / P21453 / sphingosine-1-phosphate receptor 1ENSG0000017098919
S1PR5 / Q9H228 / sphingosine-1-phosphate receptor 5ENSG0000018073918
S1PR4 / O95977 / sphingosine-1-phosphate receptor 4ENSG0000012591018
S1PR2 / O95136 / sphingosine-1-phosphate receptor 2ENSG0000026753418
GPR6 / P46095 / G protein-coupled receptor 6ENSG0000014636017
LPAR2 / Q9HBW0 / lysophosphatidic acid receptor 2ENSG0000006454717
LPAR3 / Q9UBY5 / lysophosphatidic acid receptor 3ENSG0000017151717
GPR12 / P47775 / G protein-coupled receptor 12ENSG0000013297516
GPR3 / P46089 / G protein-coupled receptor 3ENSG0000018177316


Protein motifs (from Interpro)
Interpro ID Name
 IPR000276  G protein-coupled receptor, rhodopsin-like
 IPR000810  Cannabinoid receptor type 1
 IPR002230  Cannabinoid receptor family
 IPR017452  GPCR, rhodopsin-like, 7TM


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0002866 positive regulation of acute inflammatory response to antigenic stimulus IEA
 biological_processGO:0007165 signal transduction IEA
 biological_processGO:0007186 G-protein coupled receptor signaling pathway IEA
 biological_processGO:0007187 G-protein coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger TAS
 biological_processGO:0007188 adenylate cyclase-modulating G-protein coupled receptor signaling pathway IEA
 biological_processGO:0007283 spermatogenesis IEA
 biological_processGO:0007413 axonal fasciculation IEA
 biological_processGO:0007568 aging IEA
 biological_processGO:0007584 response to nutrient IEA
 biological_processGO:0007611 learning or memory IEA
 biological_processGO:0007613 memory IEA
 biological_processGO:0010976 positive regulation of neuron projection development IEA
 biological_processGO:0019216 regulation of lipid metabolic process IEA
 biological_processGO:0019233 sensory perception of pain IEA
 biological_processGO:0031622 positive regulation of fever generation IEA
 biological_processGO:0031999 negative regulation of fatty acid beta-oxidation IEA
 biological_processGO:0032228 regulation of synaptic transmission, GABAergic IEA
 biological_processGO:0032496 response to lipopolysaccharide IEA
 biological_processGO:0033004 negative regulation of mast cell activation IEA
 biological_processGO:0033602 negative regulation of dopamine secretion IEA
 biological_processGO:0035094 response to nicotine IEA
 biological_processGO:0038171 cannabinoid signaling pathway IEA
 biological_processGO:0042220 response to cocaine IEA
 biological_processGO:0042593 glucose homeostasis IEA
 biological_processGO:0043065 positive regulation of apoptotic process IEA
 biological_processGO:0043271 negative regulation of ion transport IEA
 biological_processGO:0043278 response to morphine IEA
 biological_processGO:0045471 response to ethanol IEA
 biological_processGO:0045759 negative regulation of action potential IEA
 biological_processGO:0045776 negative regulation of blood pressure IEA
 biological_processGO:0045777 positive regulation of blood pressure IEA
 biological_processGO:0050796 regulation of insulin secretion IEA
 biological_processGO:0051001 negative regulation of nitric-oxide synthase activity IEA
 biological_processGO:0051966 regulation of synaptic transmission, glutamatergic IEA
 biological_processGO:0060135 maternal process involved in female pregnancy IEA
 biological_processGO:0060259 regulation of feeding behavior IEA
 biological_processGO:0060405 regulation of penile erection IEA
 biological_processGO:0099553 trans-synaptic signaling by endocannabinoid, modulating synaptic transmission IEA
 cellular_componentGO:0005739 mitochondrion IEA
 cellular_componentGO:0005741 mitochondrial outer membrane IEA
 cellular_componentGO:0005886 plasma membrane TAS
 cellular_componentGO:0005887 integral component of plasma membrane TAS
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 cellular_componentGO:0030424 axon IEA
 cellular_componentGO:0030426 growth cone IEA
 cellular_componentGO:0042734 presynaptic membrane IEA
 cellular_componentGO:0042995 cell projection IEA
 cellular_componentGO:0043231 intracellular membrane-bounded organelle IEA
 cellular_componentGO:0045121 membrane raft IEA
 molecular_functionGO:0004871 obsolete signal transducer activity IEA
 molecular_functionGO:0004930 G-protein coupled receptor activity IEA
 molecular_functionGO:0004949 cannabinoid receptor activity IEA
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0008144 drug binding IEA


Pathways (from Reactome)
Pathway description
Class A/1 (Rhodopsin-like receptors)
G alpha (i) signalling events


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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