ENSG00000146360


Homo sapiens

Features
Gene ID: ENSG00000146360
  
Biological name :GPR6
  
Synonyms : GPR6 / G protein-coupled receptor 6 / P46095
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 6
Strand: 1
Band: q21
Gene start: 109978256
Gene end: 109980718
  
Corresponding Affymetrix probe sets: 1553507_a_at (Human Genome U133 Plus 2.0 Array)   214655_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000275169
Ensembl peptide - ENSP00000406986
NCBI entrez gene - 2830     See in Manteia.
OMIM - 600553
RefSeq - NM_001286099
RefSeq - NM_005284
RefSeq Peptide - NP_001273028
RefSeq Peptide - NP_005275
swissprot - P46095
swissprot - F1DAM6
Ensembl - ENSG00000146360
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 gpr6ENSDARG00000052400Danio rerio
 GPR6ENSGALG00000015068Gallus gallus
 Gpr6ENSMUSG00000046922Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
GPR3 / P46089 / G protein-coupled receptor 3ENSG0000018177351
GPR12 / P47775 / G protein-coupled receptor 12ENSG0000013297550
S1PR5 / Q9H228 / sphingosine-1-phosphate receptor 5ENSG0000018073926
LPAR2 / Q9HBW0 / lysophosphatidic acid receptor 2ENSG0000006454725
S1PR2 / O95136 / sphingosine-1-phosphate receptor 2ENSG0000026753424
S1PR3 / Q99500 / sphingosine-1-phosphate receptor 3ENSG0000021369423
S1PR1 / P21453 / sphingosine-1-phosphate receptor 1ENSG0000017098923
CNR1 / P21554 / cannabinoid receptor 1ENSG0000011843221
S1PR4 / O95977 / sphingosine-1-phosphate receptor 4ENSG0000012591021
CNR2 / P34972 / cannabinoid receptor 2ENSG0000018882220
LPAR3 / Q9UBY5 / lysophosphatidic acid receptor 3ENSG0000017151720
LPAR1 / Q92633 / lysophosphatidic acid receptor 1ENSG0000019812120


Protein motifs (from Interpro)
Interpro ID Name
 IPR000276  G protein-coupled receptor, rhodopsin-like
 IPR000723  G protein-coupled receptor 3/6/12 orphan
 IPR001151  G protein-coupled receptor 6
 IPR017452  GPCR, rhodopsin-like, 7TM


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0003376 sphingosine-1-phosphate signaling pathway IEA
 biological_processGO:0007165 signal transduction IEA
 biological_processGO:0007186 G-protein coupled receptor signaling pathway TAS
 biological_processGO:0007204 positive regulation of cytosolic calcium ion concentration IEA
 cellular_componentGO:0005886 plasma membrane IEA
 cellular_componentGO:0005887 integral component of plasma membrane TAS
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 molecular_functionGO:0004871 obsolete signal transducer activity IEA
 molecular_functionGO:0004930 G-protein coupled receptor activity TAS
 molecular_functionGO:0038036 sphingosine-1-phosphate receptor activity IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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