ENSG00000064547


Homo sapiens

Features
Gene ID: ENSG00000064547
  
Biological name :LPAR2
  
Synonyms : LPAR2 / lysophosphatidic acid receptor 2 / Q9HBW0
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 19
Strand: -1
Band: p13.11
Gene start: 19623668
Gene end: 19628930
  
Corresponding Affymetrix probe sets: 206722_s_at (Human Genome U133 Plus 2.0 Array)   206723_s_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000466940
Ensembl peptide - ENSP00000466112
Ensembl peptide - ENSP00000468132
Ensembl peptide - ENSP00000384665
Ensembl peptide - ENSP00000443256
Ensembl peptide - ENSP00000465206
Ensembl peptide - ENSP00000465280
NCBI entrez gene - 9170     See in Manteia.
OMIM - 605110
RefSeq - XM_017027469
RefSeq - NM_004720
RefSeq - XM_011528421
RefSeq - XM_017027468
RefSeq Peptide - NP_004711
swissprot - A0A024R7M9
swissprot - K7ER68
swissprot - K7EJJ9
swissprot - K7ELJ6
swissprot - K7ENG7
swissprot - Q9HBW0
Ensembl - ENSG00000064547
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 lpar2aENSDARG00000042338Danio rerio
 lpar2bENSDARG00000042561Danio rerio
 Lpar2ENSMUSG00000031861Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
LPAR1 / Q92633 / lysophosphatidic acid receptor 1ENSG0000019812152
LPAR3 / Q9UBY5 / lysophosphatidic acid receptor 3ENSG0000017151745
S1PR4 / O95977 / sphingosine-1-phosphate receptor 4ENSG0000012591033
S1PR1 / P21453 / sphingosine-1-phosphate receptor 1ENSG0000017098933
S1PR2 / O95136 / sphingosine-1-phosphate receptor 2ENSG0000026753432
S1PR3 / Q99500 / sphingosine-1-phosphate receptor 3ENSG0000021369432
S1PR5 / Q9H228 / sphingosine-1-phosphate receptor 5ENSG0000018073932
GPR6 / P46095 / G protein-coupled receptor 6ENSG0000014636027
GPR3 / P46089 / G protein-coupled receptor 3ENSG0000018177327
GPR12 / P47775 / G protein-coupled receptor 12ENSG0000013297525
CNR1 / P21554 / cannabinoid receptor 1ENSG0000011843223
CNR2 / P34972 / cannabinoid receptor 2ENSG0000018882222


Protein motifs (from Interpro)
Interpro ID Name
 IPR000276  G protein-coupled receptor, rhodopsin-like
 IPR004065  Lysophosphatidic acid receptor
 IPR004066  Lysophosphatidic acid receptor EDG-4
 IPR017452  GPCR, rhodopsin-like, 7TM


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0007165 signal transduction IEA
 biological_processGO:0007186 G-protein coupled receptor signaling pathway IEA
 biological_processGO:0007202 activation of phospholipase C activity TAS
 biological_processGO:0007204 positive regulation of cytosolic calcium ion concentration TAS
 cellular_componentGO:0005886 plasma membrane TAS
 cellular_componentGO:0005887 integral component of plasma membrane TAS
 cellular_componentGO:0009986 cell surface IEA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 cellular_componentGO:0030139 endocytic vesicle IDA
 molecular_functionGO:0004871 obsolete signal transducer activity IEA
 molecular_functionGO:0004930 G-protein coupled receptor activity IEA
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0008289 lipid binding TAS
 molecular_functionGO:0070915 lysophosphatidic acid receptor activity IEA


Pathways (from Reactome)
Pathway description
G alpha (q) signalling events
G alpha (i) signalling events
Lysosphingolipid and LPA receptors


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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