ENSG00000171517


Homo sapiens

Features
Gene ID: ENSG00000171517
  
Biological name :LPAR3
  
Synonyms : LPAR3 / lysophosphatidic acid receptor 3 / Q9UBY5
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 1
Strand: -1
Band: p22.3
Gene start: 84811602
Gene end: 84893213
  
Corresponding Affymetrix probe sets: 220816_at (Human Genome U133 Plus 2.0 Array)   231192_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000395389
Ensembl peptide - ENSP00000359643
NCBI entrez gene - 23566     See in Manteia.
OMIM - 605106
RefSeq - NM_012152
RefSeq Peptide - NP_036284
swissprot - Q9UBY5
Ensembl - ENSG00000171517
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 lpar3ENSDARG00000101814Danio rerio
 LPAR3ENSGALG00000008733Gallus gallus
 Lpar3ENSMUSG00000036832Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
LPAR1 / Q92633 / lysophosphatidic acid receptor 1ENSG0000019812148
LPAR2 / Q9HBW0 / lysophosphatidic acid receptor 2ENSG0000006454745
S1PR1 / P21453 / sphingosine-1-phosphate receptor 1ENSG0000017098931
S1PR2 / O95136 / sphingosine-1-phosphate receptor 2ENSG0000026753430
S1PR3 / Q99500 / sphingosine-1-phosphate receptor 3ENSG0000021369430
S1PR4 / O95977 / sphingosine-1-phosphate receptor 4ENSG0000012591028
S1PR5 / Q9H228 / sphingosine-1-phosphate receptor 5ENSG0000018073927
GPR3 / P46089 / G protein-coupled receptor 3ENSG0000018177323
CNR1 / P21554 / cannabinoid receptor 1ENSG0000011843222
GPR12 / P47775 / G protein-coupled receptor 12ENSG0000013297521
GPR6 / P46095 / G protein-coupled receptor 6ENSG0000014636021
CNR2 / P34972 / cannabinoid receptor 2ENSG0000018882219


Protein motifs (from Interpro)
Interpro ID Name
 IPR000276  G protein-coupled receptor, rhodopsin-like
 IPR004065  Lysophosphatidic acid receptor
 IPR005385  Lysophosphatidic acid receptor EDG-7
 IPR017452  GPCR, rhodopsin-like, 7TM


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0000187 activation of MAPK activity IEA
 biological_processGO:0007165 signal transduction IEA
 biological_processGO:0007186 G-protein coupled receptor signaling pathway TAS
 biological_processGO:0007187 G-protein coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger TAS
 biological_processGO:0007204 positive regulation of cytosolic calcium ion concentration TAS
 biological_processGO:0007268 chemical synaptic transmission TAS
 biological_processGO:0032060 bleb assembly IEA
 biological_processGO:0043410 positive regulation of MAPK cascade IEA
 biological_processGO:0048672 positive regulation of collateral sprouting IEA
 biological_processGO:0051482 positive regulation of cytosolic calcium ion concentration involved in phospholipase C-activating G-protein coupled signaling pathway IEA
 biological_processGO:0051928 positive regulation of calcium ion transport IEA
 cellular_componentGO:0005886 plasma membrane TAS
 cellular_componentGO:0005887 integral component of plasma membrane TAS
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 cellular_componentGO:0030424 axon IEA
 molecular_functionGO:0001965 G-protein alpha-subunit binding IEA
 molecular_functionGO:0004871 obsolete signal transducer activity IEA
 molecular_functionGO:0004930 G-protein coupled receptor activity TAS
 molecular_functionGO:0005543 phospholipid binding IEA
 molecular_functionGO:0008289 lipid binding TAS
 molecular_functionGO:0070915 lysophosphatidic acid receptor activity IEA


Pathways (from Reactome)
Pathway description
G alpha (q) signalling events
G alpha (i) signalling events
Lysosphingolipid and LPA receptors


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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