ENSG00000132975


Homo sapiens

Features
Gene ID: ENSG00000132975
  
Biological name :GPR12
  
Synonyms : GPR12 / G protein-coupled receptor 12 / P47775
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 13
Strand: -1
Band: q12.13
Gene start: 26755200
Gene end: 26760785
  
Corresponding Affymetrix probe sets: 1559603_at (Human Genome U133 Plus 2.0 Array)   214558_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000370844
Ensembl peptide - ENSP00000384932
NCBI entrez gene - 2835     See in Manteia.
OMIM - 600752
RefSeq - NM_005288
RefSeq - XM_005266360
RefSeq Peptide - NP_005279
swissprot - A8K2F5
swissprot - P47775
Ensembl - ENSG00000132975
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 gpr12ENSDARG00000062934Danio rerio
 GPR12ENSGALG00000017102Gallus gallus
 Gpr12ENSMUSG00000041468Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
GPR6 / P46095 / G protein-coupled receptor 6ENSG0000014636056
GPR3 / P46089 / G protein-coupled receptor 3ENSG0000018177355
S1PR5 / Q9H228 / sphingosine-1-phosphate receptor 5ENSG0000018073929
LPAR2 / Q9HBW0 / lysophosphatidic acid receptor 2ENSG0000006454727
S1PR1 / P21453 / sphingosine-1-phosphate receptor 1ENSG0000017098926
S1PR3 / Q99500 / sphingosine-1-phosphate receptor 3ENSG0000021369425
S1PR2 / O95136 / sphingosine-1-phosphate receptor 2ENSG0000026753425
LPAR1 / Q92633 / lysophosphatidic acid receptor 1ENSG0000019812124
CNR2 / P34972 / cannabinoid receptor 2ENSG0000018882223
CNR1 / P21554 / cannabinoid receptor 1ENSG0000011843223
S1PR4 / O95977 / sphingosine-1-phosphate receptor 4ENSG0000012591023
LPAR3 / Q9UBY5 / lysophosphatidic acid receptor 3ENSG0000017151722


Protein motifs (from Interpro)
Interpro ID Name
 IPR000276  G protein-coupled receptor, rhodopsin-like
 IPR000599  G protein-coupled receptor 12
 IPR000723  G protein-coupled receptor 3/6/12 orphan
 IPR017452  GPCR, rhodopsin-like, 7TM


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006874 cellular calcium ion homeostasis IEA
 biological_processGO:0007165 signal transduction IEA
 biological_processGO:0007186 G-protein coupled receptor signaling pathway TAS
 cellular_componentGO:0005623 cell IEA
 cellular_componentGO:0005886 plasma membrane IEA
 cellular_componentGO:0005887 integral component of plasma membrane TAS
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 molecular_functionGO:0004871 obsolete signal transducer activity IEA
 molecular_functionGO:0004930 G-protein coupled receptor activity TAS
 molecular_functionGO:0031210 phosphatidylcholine binding IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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