ENSMUSG00000046922


Mus musculus

Features
Gene ID: ENSMUSG00000046922
  
Biological name :Gpr6
  
Synonyms : Gpr6 / G-protein coupled receptor 6 / Q6YNI2
  
Possible biological names infered from orthology : P46095
  
Species: Mus musculus
  
Chr. number: 10
Strand: -1
Band: B1
Gene start: 41069977
Gene end: 41072285
  
Corresponding Affymetrix probe sets: 10368780 (MoGene1.0st)   1440148_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000057323
NCBI entrez gene - 140741     See in Manteia.
MGI - MGI:2155249
RefSeq - NM_199058
RefSeq - XM_006512533
RefSeq Peptide - NP_951013
swissprot - Q6YNI2
Ensembl - ENSMUSG00000046922
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 gpr6ENSDARG00000052400Danio rerio
 GPR6ENSGALG00000015068Gallus gallus
 GPR6ENSG00000146360Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Gpr12 / P35412 / G-protein coupled receptor 12 / P47775*ENSMUSG0000004146853
Gpr3 / P35413 / G-protein coupled receptor 3 / P46089*ENSMUSG0000004964952
Lpar2 / lysophosphatidic acid receptor 2 / Q9HBW0*ENSMUSG0000003186126
S1pr5 / Q91X56 / Sphingosine 1-phosphate receptor 5 / Q9H228*ENSMUSG0000004508726
S1pr2 / P52592 / Sphingosine 1-phosphate receptor 2 / O95136*ENSMUSG0000004389525
S1pr1 / O08530 / Sphingosine 1-phosphate receptor 1 / P21453*ENSMUSG0000004509224
S1pr3 / Q9Z0U9 / Sphingosine 1-phosphate receptor 3 / Q99500*ENSMUSG0000006758624
S1pr4 / Q9Z0L1 / Sphingosine 1-phosphate receptor 4 / O95977*ENSMUSG0000004419923
Cnr2 / P47936 / Cannabinoid receptor 2 / P34972*ENSMUSG0000006258522
Cnr1 / P47746 / Mus musculus cannabinoid receptor 1 (brain) (Cnr1), transcript variant 2, mRNA. / P21554* / cannabinoid receptor 1*ENSMUSG0000004428822
Lpar3 / Q9EQ31 / Lysophosphatidic acid receptor 3 / Q9UBY5*ENSMUSG0000003683221
Lpar1 / P61793 / Lysophosphatidic acid receptor 1 / Q92633*ENSMUSG0000003866821


Protein motifs (from Interpro)
Interpro ID Name
 IPR000276  G protein-coupled receptor, rhodopsin-like
 IPR000723  G protein-coupled receptor 3/6/12 orphan
 IPR001151  G protein-coupled receptor 6
 IPR017452  GPCR, rhodopsin-like, 7TM


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0003376 sphingosine-1-phosphate signaling pathway IEA
 biological_processGO:0007165 signal transduction IEA
 biological_processGO:0007186 G-protein coupled receptor signaling pathway IEA
 biological_processGO:0007204 positive regulation of cytosolic calcium ion concentration IDA
 cellular_componentGO:0005886 plasma membrane IEA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 molecular_functionGO:0004871 obsolete signal transducer activity IEA
 molecular_functionGO:0004930 G-protein coupled receptor activity IEA
 molecular_functionGO:0038036 sphingosine-1-phosphate receptor activity IDA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0002062 abnormal conditioning behavior "inability to change the frequency or form of a behavior as a result of the influence of the environment " [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]
Show

Allelic Composition: Ptentm1Mro/Ptentm1Mro,Tg(KLK3-cre)D4Trp/0
Genetic Background: involves: 129P2/OlaHsd * FVB

 MP:0002169 no phenotype detected "normal, viable and fertile appearance and behavior; indistinguishable from controls" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]
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Allelic Composition: Seletm2Alb/Seletm2Alb,Selptm1Bay/Selptm1Bay
Genetic Background: involves: 129S7/SvEvBrd * C57BL/6J

 MP:0004077 abnormal striatum morphology "malformation of a large cluster of dopaminergic nerve cells, consisting of the caudate nucleus and the putamen, that controls movement, balance, and walking" [Principles of Neural Science , 3rd edition:ISBN 0-8385-8034-3]
Show

Allelic Composition: Ptentm1Mro/Ptentm1Mro,Tg(KLK3-cre)D4Trp/0
Genetic Background: involves: 129P2/OlaHsd * FVB

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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