12767


Mus musculus (NCBI)
cellregulationmigrationbindingdevelopmentreceptorchemokinemembraneactivityinvolvedmorphogenesisproteinchemotaxiscalciumionstimulusendosomeneuronresponseg-proteincoupledsignalinggermneurogenesisstemproliferationendothelialdifferentiationdetectionsensory

Features
Gene ID: 12767
  
Biological name :
  
Synonyms : CD184|CXC-R4|CXCR-4|Cmkar4|LESTR|PB-CKR|PBSF/SDF-1|Sdf1r|b2b220Clo / chemokine (C-X-C motif) receptor 4 / Cxcr4
  
Possible biological names infered from orthology :
  
Species: Mus musculus (NCBI)
  
Chr. number:
Strand:
Band:
Gene start:
Gene end:
  
Corresponding Affymetrix probe sets: 1448710_at (Mouse Genome 430 2.0 Array)   
  
Cross references: RefSeq - 116268123
RefSeq - 1252004247
RefSeq - 568908091
RefSeq - 568908093
RefSeq - NC_000067.6
RefSeq - NP_001343438.1
RefSeq - NP_034041.2
RefSeq - XP_006529176.1
RefSeq - XP_006529177.1
RefSeq - NM_001356509.1
RefSeq - NM_009911.3
RefSeq - XM_006529113.3
RefSeq - XM_006529114.2
  
See co-cited genes in PubMed
Warning: Please see the Ensembl gene model ENSMUSG00000045382 to get all the annotations available for this gene.


Gene Ontology (GO)
anatomical structure developmentlocalization of cellmovement of cell or subcellular componentcellular developmental processnitrogen compound metabolic processcellular metabolic processprimary metabolic processorganic substance metabolic processresponse to external stimulusresponse to chemicalimmune responsecell communicationcellular response to stimulusregulation of biological qualitymulticellular organism reproductioncellular component organizationresponse to stresscell activationleukocyte proliferationcell deathinterspecies interaction between organismssystem processdetection of stimulusresponse to abiotic stimulusestablishment of localizationneural precursor cell proliferationcell growthdevelopmental growthanatomical structure developmentlocalization of cellmovement of cell or subcellular componentcellular developmental processnitrogen compound metabolic processcellular metabolic processprimary metabolic processorganic substance metabolic processresponse to external stimulusresponse to chemicalimmune responsecell communicationcellular response to stimulusregulation of biological qualitymulticellular organism reproductioncellular component organizationresponse to stresscell activationleukocyte proliferationcell deathinterspecies interaction between organismssystem processdetection of stimulusresponse to abiotic stimulusestablishment of localizationneural precursor cell proliferationcell growthdevelopmental growthanatomical structure developmentlocalization of cellmovement of cell or subcellular componentcellular developmental processnitrogen compound metabolic processcellular metabolic processprimary metabolic processorganic substance metabolic processresponse to external stimulusresponse to chemicalimmune responsecell communicationcellular response to stimulusregulation of biological qualitymulticellular organism reproductioncellular component organizationresponse to stresscell activationleukocyte proliferationcell deathinterspecies interaction between organismssystem processdetection of stimulusresponse to abiotic stimulusestablishment of localizationneural precursor cell proliferationcell growthdevelopmental growthanatomical structure developmentlocalization of cellmovement of cell or subcellular componentcellular developmental processnitrogen compound metabolic processcellular metabolic processprimary metabolic processorganic substance metabolic processresponse to external stimulusresponse to chemicalimmune responsecell communicationcellular response to stimulusregulation of biological qualitymulticellular organism reproductioncellular component organizationresponse to stresscell activationleukocyte proliferationcell deathinterspecies interaction between organismssystem processdetection of stimulusresponse to abiotic stimulusestablishment of localizationneural precursor cell proliferationcell growthdevelopmental growthanatomical structure developmentlocalization of cellmovement of cell or subcellular componentcellular developmental processnitrogen compound metabolic processcellular metabolic processprimary metabolic processorganic substance metabolic processresponse to external stimulusresponse to chemicalimmune responsecell communicationcellular response to stimulusregulation of biological qualitymulticellular organism reproductioncellular component organizationresponse to stresscell activationleukocyte proliferationcell deathinterspecies interaction between organismssystem processdetection of stimulusresponse to abiotic stimulusestablishment of localizationneural precursor cell proliferationcell growthdevelopmental growthanatomical structure developmentlocalization of cellmovement of cell or subcellular componentcellular developmental processnitrogen compound metabolic processcellular metabolic processprimary metabolic processorganic substance metabolic processresponse to external stimulusresponse to chemicalimmune responsecell communicationcellular response to stimulusregulation of biological qualitymulticellular organism reproductioncellular component organizationresponse to stresscell activationleukocyte proliferationcell deathinterspecies interaction between organismssystem processdetection of stimulusresponse to abiotic stimulusestablishment of localizationneural precursor cell proliferationcell growthdevelopmental growthanatomical structure developmentlocalization of cellmovement of cell or subcellular componentcellular developmental processnitrogen compound metabolic processcellular metabolic processprimary metabolic processorganic substance metabolic processresponse to external stimulusresponse to chemicalimmune responsecell communicationcellular response to stimulusregulation of biological qualitymulticellular organism reproductioncellular component organizationresponse to stresscell activationleukocyte proliferationcell deathinterspecies interaction between organismssystem processdetection of stimulusresponse to abiotic stimulusestablishment of localizationneural precursor cell proliferationcell growthdevelopmental growthanatomical structure developmentlocalization of cellmovement of cell or subcellular componentcellular developmental processnitrogen compound metabolic processcellular metabolic processprimary metabolic processorganic substance metabolic processresponse to external stimulusresponse to chemicalimmune responsecell communicationcellular response to stimulusregulation of biological qualitymulticellular organism reproductioncellular component organizationresponse to stresscell activationleukocyte proliferationcell deathinterspecies interaction between organismssystem processdetection of stimulusresponse to abiotic stimulusestablishment of localizationneural precursor cell proliferationcell growthdevelopmental growthanatomical structure developmentlocalization of cellmovement of cell or subcellular componentcellular developmental processnitrogen compound metabolic processcellular metabolic processprimary metabolic processorganic substance metabolic processresponse to external stimulusresponse to chemicalimmune responsecell communicationcellular response to stimulusregulation of biological qualitymulticellular organism reproductioncellular component organizationresponse to stresscell activationleukocyte proliferationcell deathinterspecies interaction between organismssystem processdetection of stimulusresponse to abiotic stimulusestablishment of localizationneural precursor cell proliferationcell growthdevelopmental growthanatomical structure developmentlocalization of cellmovement of cell or subcellular componentcellular developmental processnitrogen compound metabolic processcellular metabolic processprimary metabolic processorganic substance metabolic processresponse to external stimulusresponse to chemicalimmune responsecell communicationcellular response to stimulusregulation of biological qualitymulticellular organism reproductioncellular component organizationresponse to stresscell activationleukocyte proliferationcell deathinterspecies interaction between organismssystem processdetection of stimulusresponse to abiotic stimulusestablishment of localizationneural precursor cell proliferationcell growthdevelopmental growthanatoanatomical structure developmentlocallocalization of cellmovemmovement of cell or subcellular componentcellucellular developmental processnitronitrogen compound metabolic processcellucellular metabolic processprimaprimary metabolic processorganorganic substance metabolic processresporesponse to external stimulusresporesponse to chemicalimmunimmune responsecell cell communicationcellucellular response to stimulusregulregulation of biological qualitymultimulticellular organism reproductioncellucellular component organizationresporesponse to stresscell cell activationleukoleukocyte proliferationcell cell deathinterinterspecies interaction between organismssystesystem processdetecdetection of stimulusresporesponse to abiotic stimulusestabestablishment of localizationneuraneural precursor cell proliferationcell cell growthdeveldevelopmental growth
protein bindingsignaling receptor activitydrug bindingprotein bindingsignaling receptor activitydrug bindingprotein bindingsignaling receptor activitydrug bindingprotein bindingsignaling receptor activitydrug bindingprotein bindingsignaling receptor activitydrug bindingprotein bindingsignaling receptor activitydrug bindingprotein bindingsignaling receptor activitydrug bindingprotein bindingsignaling receptor activitydrug bindingprotein bindingsignaling receptor activitydrug bindingprotein bindingsignaling receptor activitydrug bindingprotein bindingprotein bindingsignaling receptor activitysignaling receptor activitydrug bindingdrug binding
cellorganellemembranecell junctionprotein-containing complexcellorganellemembranecell junctionprotein-containing complexcellorganellemembranecell junctionprotein-containing complexcellorganellemembranecell junctionprotein-containing complexcellorganellemembranecell junctionprotein-containing complexcellorganellemembranecell junctionprotein-containing complexcellorganellemembranecell junctionprotein-containing complexcellorganellemembranecell junctionprotein-containing complexcellorganellemembranecell junctionprotein-containing complexcellorganellemembranecell junctionprotein-containing complexcellcellorganelleorganellemembranemembranecell junctioncell junctionprotein-containing complexprotein-containing complex
TypeGO IDTermEv.Code
 biological_processGO:0001569 branching involved in blood vessel morphogenesis IMP
 biological_processGO:0001667 ameboidal-type cell migration IMP
 biological_processGO:0001764 neuron migration ISO
 biological_processGO:0001934 positive regulation of protein phosphorylation IMP
 biological_processGO:0002064 epithelial cell development ISO
 biological_processGO:0003281 ventricular septum development IMP
 biological_processGO:0006935 chemotaxis IEA
 biological_processGO:0006955 immune response IBA
 biological_processGO:0007165 signal transduction IEA
 biological_processGO:0007186 G-protein coupled receptor signaling pathway ISO
 biological_processGO:0007204 positive regulation of cytosolic calcium ion concentration IBA
 biological_processGO:0007281 germ cell development IMP
 biological_processGO:0007399 nervous system development TAS
 biological_processGO:0007420 brain development IMP
 biological_processGO:0008045 motor neuron axon guidance IMP
 biological_processGO:0008354 germ cell migration IMP
 biological_processGO:0009887 animal organ morphogenesis TAS
 biological_processGO:0016477 cell migration ISO
 biological_processGO:0019722 calcium-mediated signaling ISO
 biological_processGO:0022008 neurogenesis ISO
 biological_processGO:0022029 telencephalon cell migration ISO
 biological_processGO:0030334 regulation of cell migration IMP
 biological_processGO:0030335 positive regulation of cell migration ISO
 biological_processGO:0035470 positive regulation of vascular wound healing ISO
 biological_processGO:0035701 hematopoietic stem cell migration IMP
 biological_processGO:0035904 aorta development IMP
 biological_processGO:0042098 T cell proliferation IMP
 biological_processGO:0043067 regulation of programmed cell death ISO
 biological_processGO:0043217 myelin maintenance IMP
 biological_processGO:0045446 endothelial cell differentiation ISO
 biological_processGO:0048699 generation of neurons IEP
 biological_processGO:0048714 positive regulation of oligodendrocyte differentiation IMP
 biological_processGO:0050769 positive regulation of neurogenesis ISO
 biological_processGO:0050792 regulation of viral process ISO
 biological_processGO:0050920 regulation of chemotaxis ISO
 biological_processGO:0050965 detection of temperature stimulus involved in sensory perception of pain ISO
 biological_processGO:0050966 detection of mechanical stimulus involved in sensory perception of pain ISO
 biological_processGO:0051924 regulation of calcium ion transport ISO
 biological_processGO:0060048 cardiac muscle contraction ISO
 biological_processGO:0060326 cell chemotaxis IBA
 biological_processGO:0061154 endothelial tube morphogenesis ISO
 biological_processGO:0061351 neural precursor cell proliferation IEP
 biological_processGO:0071345 cellular response to cytokine stimulus ISO
 biological_processGO:0090280 positive regulation of calcium ion import IDA
 biological_processGO:1903861 positive regulation of dendrite extension ISO
 biological_processGO:1905322 positive regulation of mesenchymal stem cell migration ISO
 cellular_componentGO:0005737 cytoplasm ISO
 cellular_componentGO:0005764 lysosome ISO
 cellular_componentGO:0005768 endosome ISO
 cellular_componentGO:0005769 early endosome ISO
 cellular_componentGO:0005770 late endosome ISO
 cellular_componentGO:0005886 plasma membrane ISO
 cellular_componentGO:0005911 cell-cell junction IDA
 cellular_componentGO:0009897 external side of plasma membrane IDA
 cellular_componentGO:0009986 cell surface ISO
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 cellular_componentGO:0030054 cell junction IEA
 cellular_componentGO:0030426 growth cone IDA
 cellular_componentGO:0031252 cell leading edge ISO
 cellular_componentGO:0031410 cytoplasmic vesicle ISO
 cellular_componentGO:0032991 protein-containing complex ISO
 molecular_functionGO:0003779 actin binding ISO
 molecular_functionGO:0004930 G-protein coupled receptor activity IEA
 molecular_functionGO:0004950 chemokine receptor activity IEA
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0008144 drug binding ISO
 molecular_functionGO:0016493 C-C chemokine receptor activity IBA
 molecular_functionGO:0016494 C-X-C chemokine receptor activity ISO
 molecular_functionGO:0019955 cytokine binding IEA
 molecular_functionGO:0019956 chemokine binding IBA
 molecular_functionGO:0019957 C-C chemokine binding ISO
 molecular_functionGO:0031625 ubiquitin protein ligase binding ISO
 molecular_functionGO:0032027 myosin light chain binding ISO
 molecular_functionGO:0043130 ubiquitin binding ISO


Pathways (from Reactome)
Pathway description
No match


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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